Back to search

Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and β-catenin

Data up to Jan 2025

Published2002
Citations119
References64

Total Citations Per Year

Abstract

References (64)

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

1999 • 3,566 citations

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1990 • 2,129 citations

Morphogenetic roles of classic cadherins

1995 • 1,468 citations

The Hedgehog and Wnt signalling pathways in cancer

2001 • 1,374 citations

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

1999 • 1,291 citations

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

1996 • 1,156 citations

β-catenin: a key mediator of Wnt signaling

1998 • 746 citations

The oncogenic activation of β-catenin

1999 • 655 citations

The cadherin superfamily: diversity in form and function

2001 • 598 citations

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin).

1995 • 573 citations

E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

2001 • 532 citations

Cadherins in embryonic and neural morphogenesis

2000 • 482 citations

Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

1997 • 470 citations

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

1992 • 394 citations

The E-cadherin–catenin complex in tumour metastasis

2000 • 347 citations

Desmoplakin Is Required Early in Development for Assembly of Desmosomes and Cytoskeletal Linkage

1998 • 336 citations

Plakoglobin and β-catenin: Protein interactions, regulation and biological roles

2000 • 334 citations

Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis

2001 • 313 citations

Neoplastic Transformation of RK3E by Mutant β-Catenin Requires Deregulation of Tcf/Lef Transcription but Not Activation of c-myc Expression

1999 • 313 citations

Role of vascular endothelial-cadherin in vascular morphogenesis

1999 • 311 citations

Functional Properties of Human Vascular Endothelial Cadherin (7B4/Cadherin-5), an Endothelium-Specific Cadherin

1995 • 273 citations

Characterization of the interactions of α-catenin with α-actinin and β-catenin/plakoglobin

1997 • 260 citations

Mechanisms regulating endothelial cell barrier function

2000 • 244 citations

Functional Roles for PECAM-1 (CD31) and VE-Cadherin (CD144. in Tube Assembly and Lumen Formation in Three-Dimensional Collagen Gels

1999 • 243 citations

Vascular Endothelial (VE)-Cadherin: Only an Intercellular Glue?

1999 • 238 citations

Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly.

1994 • 234 citations

γ-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of β-catenin

2000 • 223 citations

Catenin-dependent and -independent Functions of Vascular Endothelial Cadherin

1995 • 220 citations

VE-Cadherin Mediates Endothelial Cell Capillary Tube Formation in Fibrin and Collagen Gels1

1998 • 216 citations

Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin.

1997 • 209 citations

Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature

2001 • 181 citations

Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes

1996 • 165 citations

Curbing the nuclear activities of β‐catenin

2000 • 163 citations

Regulation of β-Catenin Levels and Localization by Overexpression of Plakoglobin and Inhibition of the Ubiquitin-Proteasome System

1997 • 157 citations

Carcinogenesis: A balance between β-catenin and APC

1997 • 154 citations

Cadherin Cell Adhesion Molecules in Differentiation and Embryogenesis

1996 • 148 citations

The Morphogenetic Role of Cadherin Cell Adhesion Molecules in Human Cancer: A Thematic Review

1998 • 141 citations

VE-cadherin and desmoplakin are assembled into dermal microvascular endothelial intercellular junctions: A pivotal role for plakoglobin in the recruitment of desmoplakin to intercellular junctions

1998 • 129 citations

Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis.

2000 • 128 citations

Complexus adhaerentes, a new group of desmoplakin-containing junctions in endothelial cells: the syndesmos connecting retothelial cells of lymph nodes.

1993 • 127 citations

Identification of a Wnt-Responsive Signal Transduction Pathway in Primary Endothelial Cells

1999 • 123 citations

Plakoglobin Suppresses Epithelial Proliferation and Hair Growth in Vivo

2000 • 118 citations

β-Catenin, an Inducer of Uncontrolled Cell Proliferation and Migration in Malignancies, Is Localized in the Cytoplasm of Vascular Endothelium during Neovascularization after Myocardial Infarction

2000 • 110 citations

Complexus adhaerentes, a new group of desmoplakin-containing junctions in endothelial cells: II. Different types of lymphatic vessels

1994 • 107 citations

Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability.

1994 • 102 citations

TCF-4 binds β-catenin and is expressed in distinct regions of the embryonic brain and limbs

1998 • 102 citations

Role of cadherins and plakoglobin in interendothelial adhesion under resting conditions and shear stress

1997 • 96 citations

Plakoglobin Regulates the Expression of the Anti-apoptotic Protein BCL-2

2000 • 92 citations

Mechanism of extracellular domain-deleted dominant negative cadherins

1999 • 90 citations

Angiogenesis and the skin: A primer

1996 • 86 citations

Rearrangement of adherens junctions by transforming growth factor-β1: role of contraction

1999 • 79 citations

Desmoplakin expression and organization at human umbilical vein endothelial cell-to-cell junctions

1996 • 76 citations

Delayed Assembly of Desmosomes in Keratinocytes with Disrupted Classic-Cadherin-Mediated Cell Adhesion by a Dominant Negative Mutant

1995 • 74 citations

She Made Me Go out of My Mind: Marital violence from the male point of view

2001 • 73 citations

Cadherin function in junctional complex rearrangement and posttranslational control of cadherin expression

1999 • 67 citations

A comparative evaluation of β-catenin and plakoglobin signaling activity

2000 • 65 citations

Contributions of extracellular and intracellular domains of full length and chimeric cadherin molecules to junction assembly in epithelial cells

1998 • 65 citations

Identification and Cloning of a Secreted Protein Related to the Cysteine-Rich Domain of Frizzled

1999 • 54 citations

Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own

1999 • 48 citations

Control over Wnt target gene expression

2000 • 45 citations

The Dual Role of Cytoskeletal Anchor Proteins in Cell Adhesion and Signal Transduction

1999 • 38 citations

Basolateral distribution of fibronectin matrix assembly sites on vascular endothelial monolayers is regulated by substratum fibronectin

1992 • 22 citations

Platelet Endothelial Cell Adhesion Molecule-1 and Vascular Endothelial Cadherin Cooperatively Regulate Fibroblast Growth Factor-induced Modulations of Adherens Junction Functions

2001 • 14 citations

Cited By (0)

No citing papers found in database

Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and… (2002) – AJP Cell Physiology | Metascience Observatory Explorer