Cadherin function in junctional complex rearrangement and posttranslational control of cadherin expression

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Occludin: a novel integral membrane protein localizing at tight junctions.

1993 • 2,466 citations

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 • 1,588 citations

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Structural basis of cell-cell adhesion by cadherins

1995 • 1,173 citations

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

1994 • 949 citations

Cell binding function of E-cadherin is regulated by the cytoplasmic domain.

1988 • 811 citations

The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex.

1988 • 810 citations

Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.

1990 • 753 citations

Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

1987 • 752 citations

Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex.

1995 • 739 citations

Structural basis of calcium-induced E-cadherin rigidification and dimerization

1996 • 688 citations

Expressed recombinant cadherins mediate cell sorting in model systems

1988 • 673 citations

Signal transduction through beta-catenin and specification of cell fate during embryogenesis.

1996 • 663 citations

Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin Filaments

1997 • 659 citations

Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly.

1994 • 633 citations

A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin

1991 • 632 citations

Assembly of the cadherin-catenin complex in vitro with recombinant proteins

1994 • 557 citations

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways

1997 • 543 citations

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

1991 • 520 citations

A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide.

1986 • 510 citations

The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression

1991 • 501 citations

Calcium-dependent cell-cell adhesion molecules (cadherins): subclass specificities and possible involvement of actin bundles.

1987 • 432 citations

Solution Structure of the Epithelial Cadherin Domain Responsible for Selective Cell Adhesion

1995 • 414 citations

Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line.

1994 • 405 citations

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

1992 • 394 citations

Expression of recombinant plasmids in mammalian cells Is enhanced by sodium butyrate

1983 • 380 citations

The uvomorulin-anchorage protein alpha catenin is a vinculin homologue.

1991 • 364 citations

Molecular linkage between cadherins and actin filaments in cell—cell adherens junctions

1992 • 359 citations

Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

1997 • 357 citations

Desmosomes and hemidesmosomes: structure and function of molecular components

1996 • 350 citations

Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex.

1995 • 341 citations

Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.

1996 • 328 citations

Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion.

1996 • 316 citations

Lateral dimerization is required for the homophilic binding activity of C-cadherin.

1996 • 307 citations

The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion.

1987 • 304 citations

Identification of a putative cell adhesion domain of uvomorulin.

1985 • 246 citations

A Short Core Region of E-cadherin is Essential for Catenin Binding and is Highly Phosphorylated

1994 • 234 citations

Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells.

1991 • 226 citations

Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein.

1989 • 223 citations

Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells.

1995 • 211 citations

Structure and interactions of desmosomal and other cadherins

1992 • 201 citations

Mechanism for transition from initial to stable cell-cell adhesion: kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay.

1996 • 200 citations

Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin.

1993 • 199 citations

Tight junctions

1998 • 197 citations

Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. II. Morphological analysis.

1988 • 194 citations

Biogenesis of tight junctions: The c-terminal domain of occludin mediates basolateral targeting

1998 • 193 citations

Modulation of fodrin (membrane skeleton) stability by cell-cell contact in Madin-Darby canine kidney epithelial cells.

1987 • 178 citations

Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cells.

1988 • 165 citations

Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes

1996 • 165 citations

Distinguishing roles of the membrane-cytoskeleton and cadherin mediated cell-cell adhesion in generating different Na+,K(+)-ATPase distributions in polarized epithelia.

1993 • 155 citations

Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion.

1993 • 153 citations

Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. I. Biochemical analysis.

1988 • 119 citations

Isolation of the cDNA encoding glycoprotein-2 (GP-2), the major zymogen granule membrane protein

1991 • 95 citations

Chapter 11 Cytomegalovirus Plasmid Vectors for Permanent Lines of Polarized Epithelial Cells

1994 • 90 citations

Delayed Assembly of Desmosomes in Keratinocytes with Disrupted Classic-Cadherin-Mediated Cell Adhesion by a Dominant Negative Mutant

1995 • 74 citations

Transmembrane control of cadherin-mediated cell-cell adhesion

1993 • 73 citations

Molecular Dissection of Tight Junctions.

1996 • 63 citations

Epithelial cell adhesion and development of cell surface polarity: possible mechanisms for modulation of cadherin function, organization and distribution

1993 • 52 citations

Polarized expression of functional rat liver asialoglycoprotein receptor in transfected Madin-Darby canine kidney cells.

1990 • 41 citations

Chapter 11 Protein Interactions in the Tight Junction: The Role of MAGUK Proteins in Regulating Tight Junction Organization and Function

1996 • 25 citations

Nucleotide sequence encoding the major glycoprotein (GP2) of rat pancreatic secretory (zymogen) granule membranes

1990 • 18 citations

Polarized GP2 secretion in MDCK cells via GPI targeting and apical membrane-restricted proteolysis

1996 • 17 citations