Mature But Not Immature Fas Ligand (CD95L)-Transduced Human Monocyte-Derived Dendritic Cells Are Protected from Fas-Mediated Apoptosis and Can Be Used as Killer APC

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1997 • 1,179 citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

1998 • 789 citations

Downregulation of Fas ligand by shedding

1998 • 681 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Membrane Fas Ligand Kills Human Peripheral Blood T Lymphocytes, and Soluble Fas Ligand Blocks the Killing

1997 • 503 citations

Methods for construction of adenovirus vectors

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Immune escape of tumors: apoptosis resistance and tumor counterattack

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Flt3 ligand induces tumor regression and antitumor immune responses in vivo

1997 • 315 citations

Dendritic Cells Genetically Engineered to Express Fas Ligand Induce Donor-Specific Hyporesponsiveness and Prolong Allograft Survival

2000 • 237 citations

Opposing Effects of Transmembrane and Soluble FAS Ligand Expression on Inflammation and Tumor Cell Survival

2000 • 236 citations

FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction

2000 • 230 citations

Recombinant adenovirus is an efficient and non-perturbing genetic vector for human dendritic cells

1999 • 226 citations

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2001 • 180 citations

Soluble Fas Ligand Is Chemotactic for Human Neutrophilic Polymorphonuclear Leukocytes

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1999 • 159 citations

Chemotactic activity of soluble Fas ligand against phagocytes.

1998 • 159 citations

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1999 • 131 citations

Dendritic Cells Are Resistant to Apoptosis Through the Fas (CD95/APO-1) Pathway

1999 • 124 citations

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1998 • 123 citations

Apoptosis of mouse naive T cells induced by recombinant soluble Fas ligand and activation-induced resistance to Fas ligand.

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Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide

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Expression of c-FLIPL and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide

2000 • 95 citations

Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: A potential treatment strategy for Epstein-Barr virus-positive Hodgkin's lymphoma

2001 • 86 citations

Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen-presenting cells

1998 • 86 citations

CD40 ligand inhibits Fas/CD95‐mediated apoptosis of human blood‐derived dendritic cells

1997 • 81 citations

Membrane Fas Ligand Activates Innate Immunity and Terminates Ocular Immune Privilege

2002 • 81 citations

Ultraviolet Light-Induced Immune Tolerance Is Mediated via the Fas/Fas-Ligand System

1998 • 74 citations

Mature dendritic cells are protected from Fas/CD95-mediated apoptosis by upregulation of Bcl-X L

2002 • 59 citations

Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand–deficient mice

2000 • 57 citations

Increased Survival in Sepsis by In Vivo Adenovirus-Induced Expression of IL-10 in Dendritic Cells

2002 • 56 citations

Feasibility of CTLA4Ig gene delivery and expression in vivo using retrovirally transduced myeloid dendritic cells that induce alloantigen-specific T cell anergy in vitro

2000 • 51 citations

Treatment of chronic sialadenitis in a murine model of Sj�gren's syndrome by localfasL gene transfer

2001 • 50 citations

Retroviral delivery of transforming growth factor-??1 to myeloid dendritic cells: inhibition of T-cell priming ability and influence on allograft survival12

2002 • 46 citations

Immunosuppressive properties of CD95L-transduced “killer” hybrids created by fusing donor- and recipient-derived dendritic cells

2001 • 45 citations

Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation

2002 • 38 citations

Application of a Fas Ligand Encoding a Recombinant Adenovirus Vector for Prolongation of Transgene Expression

1998 • 33 citations

Dendritic Cells for Specific Cancer Immunotherapy

2001 • 29 citations

Killing of naive T cells by CD95L-transfected dendritic cells (DC):in vivo study using killer DC-DC hybrids and CD4+ T cells from DO11.10 mice

2002 • 26 citations

Down-regulation of human alloimmune responses by genetically engineered expression of CD95 ligand on stimulatory and target cells

2001 • 26 citations

Reduction of Antiviral CD8 Lymphocytes In Vivo with Dendritic Cells Expressing Fas Ligand—Increased Survival of Viral (Lymphocytic Choriomeningitis Virus) Central Nervous System Infection

2002 • 25 citations

Antigen-Specific Induction of Peripheral T Cell Tolerancein Vivoby Codelivery of DNA Vectors Encoding Antigen and Fas Ligand

2000 • 24 citations

Specific Immunotherapy by Genetically Engineered APCs: The “Guided Missile” Strategy

2001 • 23 citations

Construction, Propagation, and Titer Estimation of Recombinant Adenoviruses Carrying Proapoptotic Genes

1998 • 18 citations

Construction of a recombinant adenovirus vector encoding fas ligand with a CRE/Loxp inducible system

1999 • 13 citations

B cells engineered to express Fas ligand suppress pre-sensitized antigen-specific T cell responses in vivo

2002 • 11 citations