Specific Immunotherapy by Genetically Engineered APCs: The “Guided Missile” Strategy

The Fas Death Factor

1995 • 4,070 citations

Cellular and Molecular Immunology

1994 • 3,469 citations

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Myasthenia Gravis

1997 • 2,469 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

The Biochemistry and Cell Biology of Antigen Processing and Presentation

1993 • 1,022 citations

Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.

1996 • 992 citations

MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 • 973 citations

The complete DNA sequence of vaccinia virus

1990 • 847 citations

Induction of antigen-specific T cell anergy: An early event in the course of tumor progression

1998 • 710 citations

Vaccinia virus: a selectable eukaryotic cloning and expression vector.

1982 • 663 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Fas transduces activation signals in normal human T lymphocytes.

1993 • 521 citations

Determinant spreading and the dynamics of the autoimmune T-cell repertoire

1993 • 467 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA

1998 • 403 citations

Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens.

1995 • 343 citations

Hierarchical Control of Lymphocyte Survival

1996 • 255 citations

T cell recognition as the target for immune intervention in autoimmune disease

1989 • 218 citations

The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.

1993 • 210 citations

Cd40-Independent Pathways of T Cell Help for Priming of Cd8+ Cytotoxic T Lymphocytes

2000 • 201 citations

The motif Tyr-X-X-hydrophobic residue mediates lysosomal membrane targeting of lysosome-associated membrane protein 1.

1993 • 169 citations

Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.

1988 • 164 citations

Dynamic Interactions of Macrophages with T Cells during Antigen Presentation

1999 • 146 citations

Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light

1996 • 136 citations

Induction of Specific T Cell Tolerance by Fas Ligand- Expressing Antigen-Presenting Cells

1999 • 131 citations

Lysosome-associated membrane protein-1-mediated targeting of the HIV-1 envelope protein to an endosomal/lysosomal compartment enhances its presentation to MHC class II-restricted T cells.

1995 • 114 citations

Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen-presenting cells

1998 • 86 citations

The Enhanced Immune Response to the HIV gp160/LAMP Chimeric Gene Product Targeted to the Lysosome Membrane Protein Trafficking Pathway

1997 • 72 citations

T Cell Receptor Signals Enhance Susceptibility to Fas-mediated Apoptosis

1997 • 72 citations

A general method for the construction of recombinant vaccinia viruses expressing multiple foreign genes

1988 • 67 citations

Lonely MHC molecules seeking immunogenic peptides for meaningful relationships

1995 • 41 citations

A vaccinia virus transfer vector using a GUS reporter gene inserted into the I4L locus

1996 • 19 citations

Specific Immunotherapy of Experimental Myasthenia Gravis in Vitro: The “Guided Missile” Strategy

2001 • 17 citations

Targeting antigen-specific T cells by genetically engineered antigen presenting cells

2000 • 15 citations

Current Neurologic Drugs

1996 • 10 citations

Non-replicating recombinant vaccinia virus encoding murine B-7 molecules elicits effective costimulation of naive CD4+ splenocytes in vitro

1996 • 7 citations