Phosphorylation by MAPK Regulates Simian Immunodeficiency Virus Vpx Protein Nuclear Import and Virus Infectivity

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The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection

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HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import

1997 • 340 citations

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1998 • 332 citations

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1998 • 328 citations

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1995 • 309 citations

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1999 • 277 citations

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1993 • 275 citations

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2001 • 273 citations

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1995 • 260 citations

Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).

1996 • 235 citations

Sequence analysis and acute pathogenicity of molecularly cloned SIVSMM-PBj14

1990 • 218 citations

Characterization of HIV-1 Vpr Nuclear Import: Analysis of Signals and Pathways

1998 • 186 citations

Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr

1997 • 179 citations

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1995 • 176 citations

Interaction of the Human Immunodeficiency Virus Type 1 Vpr Protein with the Nuclear Pore Complex

1998 • 175 citations

HIV-1, Vpr and the cell cycle

1996 • 173 citations

Identification of the Mitogen-Activated Protein Kinase Phosphorylation Sites on Human Sosl That Regulate Interaction with Grb2

1996 • 172 citations

Vpx is required for dissemination and pathogenesis of SIVSM PBj: Evidence of macrophage-dependent viral amplification

1998 • 169 citations

Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase

1998 • 156 citations

SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

2000 • 155 citations

Reassessment of the Roles of Integrase and the Central DNA Flap in Human Immunodeficiency Virus Type 1 Nuclear Import

2002 • 148 citations

Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β

1997 • 146 citations

Isolation and Characterization of a Novel Protein (X-ORF Product) from SIV and HIV-2

1988 • 141 citations

Kinase phosphorylation: Keeping it all in the family

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WW domains and retrovirus budding

1996 • 124 citations

Nucleocytoplasmic Shuttling by Human Immunodeficiency Virus Type 1 Vpr

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A Conserved Dileucine-Containing Motif in p6 ^gag Governs the Particle Association of Vpx and Vpr of Simian Immunodeficiency Viruses SIV _mac and SIV _agm

1999 • 90 citations

Wild-Type Levels of Nuclear Localization and Human Immunodeficiency Virus Type 1 Replication in the Absence of the Central DNA Flap

2002 • 86 citations

Mutational Analysis of the Nucleic Acid-Binding 17 kDa Phosphoprotein of Potato Leafroll Luteovirus Identifies an Amphipathic α-Helix as the Domain for Protein/Protein Interactions

1993 • 85 citations

Identification of Residues in the N-Terminal Acidic Domain of HIV-1 Vpr Essential for Virion Incorporation

1995 • 83 citations

Phosphorylation of Both Phosphoacceptor Sites in the HIV-1 Vpu Cytoplasmic Domain Is Essential for Vpu-Mediated ER Degradation of CD4

1997 • 77 citations

Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein

1994 • 74 citations

The Host Cell MAP Kinase ERK-2 Regulates Viral Assembly and Release by Phosphorylating the p6 Protein of HIV-1

2004 • 73 citations

Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC

1988 • 67 citations

The C-Terminal Proline-Rich Tail of Human Immunodeficiency Virus Type 2 Vpx Is Necessary for Nuclear Localization of the Viral Preintegration Complex in Nondividing Cells

2000 • 66 citations

Intracellular Transport and Virion Incorporation of vpx Requires Interaction with Other Virus Type-Specific Components

1993 • 59 citations

Active cAMP-dependent Protein Kinase Incorporated within Highly Purified HIV-1 Particles Is Required for Viral Infectivity and Interacts with Viral Capsid Protein

2003 • 56 citations

Human immunodeficiency virus type 1 Vpr localization: nuclear transport of a viral protein modulated by a putative amphipathic helical structure and its relevance to biological activity

1998 • 54 citations

Vpx Association with Mature Core Structures of HIV-2

1996 • 53 citations

Functional Analysis of the Simian Immunodeficiency Virus Vpx Protein: Identification of Packaging Determinants and a Novel Nuclear Targeting Domain

2001 • 52 citations

Cutting Edge: SIV Nef Protein Utilizes Both Leucine- and Tyrosine-Based Protein Sorting Pathways for Down-Regulation of CD4

1999 • 50 citations

Cell cycle models for molecular biology and molecular oncology: Exploring new dimensions

1999 • 45 citations

Cell cycle models for molecular biology and molecular oncology: Exploring new dimensions

1999 • 39 citations

Induction of phosphorylation of human immunodeficiency virus type 1 Nef and enhancement of CD4 downregulation by phorbol myristate acetate

1997 • 33 citations

Identification of the nuclear localization signal of human immunodeficiency virus type 2 Vpx

2003 • 27 citations

Statistical and functional analyses of viral and cellular proteins with N-terminal amphipathic alpha-helices with large hydrophobic moments: importance to macromolecular recognition and organelle targeting

1988 • 26 citations

Human immunodeficiency virus matrix tyrosine phosphorylation: characterization of the kinase and its substrate requirements

1997 • 25 citations

A Non-canonical Transferable Signal Mediates Nuclear Import of Simian Immunodeficiency Virus Vpx Protein

2003 • 21 citations

Nuclear Export of Human Immunodeficiency Virus Type 1 Vpr Is Not Required for Virion Packaging

2001 • 20 citations