The Host Cell MAP Kinase ERK-2 Regulates Viral Assembly and Release by Phosphorylating the p6 Protein of HIV-1

Tsg101 and the Vacuolar Protein Sorting Pathway Are Essential for HIV-1 Budding

2001 • 1,351 citations

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

1989 • 831 citations

AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

2003 • 810 citations

The Protein Network of HIV Budding

2003 • 806 citations

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

2001 • 706 citations

Function of WW Domains as Phosphoserine- or Phosphothreonine-Binding Modules

1999 • 663 citations

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

1991 • 644 citations

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

1990 • 634 citations

Functional association of cyclophilin A with HIV-1 virions

1994 • 632 citations

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55 ^Gag

2001 • 576 citations

p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease

1995 • 482 citations

NeW Wrinkles for an Old Domain

2000 • 349 citations

The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions

1994 • 349 citations

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function

2002 • 349 citations

Proteasome inhibition interferes with Gag polyprotein processing, release, and maturation of HIV-1 and HIV-2

2000 • 334 citations

Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2

1993 • 333 citations

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

1995 • 309 citations

Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection

1997 • 266 citations

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import

1996 • 253 citations

Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles

1993 • 228 citations

The acquisition of host-encoded proteins by nascent HIV-1

1998 • 191 citations

Host cyclophilin A mediates HIV-1 attachment to target cells via heparans

1999 • 180 citations

Ubiquitin Is Covalently Attached to the p6 ^Gag Proteins of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus and to the p12 ^Gag Protein of Moloney Murine Leukemia Virus

1998 • 162 citations

Mutations altering the Moloney murine leukemia virus p12 Gag protein affect virion production and early events of the virus life cycle

1999 • 159 citations

Translation Elongation Factor 1-Alpha Interacts Specifically with the Human Immunodeficiency Virus Type 1 Gag Polyprotein

1999 • 158 citations

Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase

1998 • 156 citations

Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

1996 • 154 citations

Inhibition of HIV-1 Replication by Cyclosporine A or Related Compounds Correlates with the Ability to Disrupt the Gag–Cyclophilin A Interaction

1996 • 142 citations

Interaction of the Human Immunodeficiency Virus Type 1 Nucleocapsid with Actin

1999 • 134 citations

Specific Incorporation of Heat Shock Protein 70 Family Members into Primate Lentiviral Virions

2002 • 131 citations

Actin-Binding Cellular Proteins inside Human Immunodeficiency Virus Type 1

2000 • 117 citations

Potential roles of cellular proteins in HIV‐1

2002 • 117 citations

The genome-associated, specific RNA binding proteins of avian and mammalian type C viruses

1977 • 113 citations

HIV-1 Gag Protein Associates with F-actin Present in Microfilaments

1996 • 108 citations

Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes

1998 • 102 citations

Actin Associates with the Nucleocapsid Domain of the Human Immunodeficiency Virus Gag Polyprotein

1999 • 101 citations

Cellular Motor Protein KIF-4 Associates with Retroviral Gag

1999 • 100 citations

The central globular domain of the nucleocapsid protein of human immunodeficiency virus type 1 is critical for virion structure and infectivity

1995 • 100 citations

Heat-Shock Protein 70 Can Replace Viral Protein R of HIV-1 during Nuclear Import of the Viral Preintegration Complex

2000 • 88 citations

Identification of Three Major Phosphorylation Sites within HIV-1 Capsid

1999 • 78 citations

Effect of Immunization with Inactivated gp120-Depleted Human Immunodeficiency Virus Type 1 (HIV-1) Immunogen on HIV-1 Immunity, Viral DNA, and Percentage of CD4 Cells

1994 • 74 citations

Polypeptides of Mason-Pfizer monkey virus I. Synthesis and processing of the gag-gene products

1984 • 74 citations

Involvement of extracellular signal-regulated kinase module in HIV-mediated CD4 signals controlling activation of nuclear factor-kappa B and AP-1 transcription factors.

1998 • 66 citations

Association of ERK2 mitogen-activated protein kinase with human immunodeficiency virus particles

1997 • 62 citations

A Human Nuclear Shuttling Protein That Interacts with Human Immunodeficiency Virus Type 1 Matrix Is Packaged into Virions

2000 • 60 citations

The Late-Domain-Containing Protein p6 Is the Predominant Phosphoprotein of Human Immunodeficiency Virus Type 1 Particles

2002 • 56 citations

Active cAMP-dependent Protein Kinase Incorporated within Highly Purified HIV-1 Particles Is Required for Viral Infectivity and Interacts with Viral Capsid Protein

2003 • 56 citations

A Bipartite Late-Budding Domain in Human Immunodeficiency Virus Type 1

2003 • 56 citations

Mutations of the Human Immunodeficiency Virus Type 1 p6 ^Gag Domain Result in Reduced Retention of Pol Proteins during Virus Assembly

1998 • 52 citations

Phosphoproteins of vesicular stomatitis virus: Identity and interco nversior of phosphorylated forms

1979 • 52 citations

Involvement of Extracellular Signal-Regulated Kinase Module in HIV-Mediated CD4 Signals Controlling Activation of Nuclear Factor-κB and AP-1 Transcription Factors

1998 • 51 citations

Particle Size Determinants in the Human Immunodeficiency Virus Type 1 Gag Protein

1998 • 51 citations

HEED, the Product of the Human Homolog of the Murineeed Gene, Binds to the Matrix Protein of HIV-1

1999 • 51 citations

Role of the C terminus Gag protein in human immunodeficiency virus type 1 virion assembly and maturation

1995 • 48 citations

Proline Residues in Human Immunodeficiency Virus Type 1 p6 ^Gag Exert a Cell Type-Dependent Effect on Viral Replication and Virion Incorporation of Pol Proteins

1999 • 45 citations

Identification of Retroviral Late Domains as Determinants of Particle Size

1999 • 30 citations

Human Immunodeficiency Virus Type 1 Matrix Protein Interacts with Cellular Protein HO3

1998 • 30 citations

Calmodulin and HIV Type 1: Interactions with Gag and Gag Products

2000 • 28 citations

Cloning and characterization of hIF2, a human homologue of bacterial translation initiation factor 2, and its interaction with HIV-1 matrix

1999 • 27 citations

Overexpression of Human Immunodeficiency Virus Type 1 Protease Increases Intracellular Cleavage of Gag and Reduces Virus Infectivity

1995 • 23 citations

Inhibition of human immunodeficiency virus type 1 production in infected peripheral blood mononuclear cells by human leukocyte antigen class I-specific antibodies: evidence for a novel antiviral mechanism

1996 • 18 citations

Virion-associated protein kinases

2002 • 17 citations