Kinase phosphorylation: Keeping it all in the family

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1998 • 1,136 citations

Protein Kinase C Isotypes Controlled by Phosphoinositide 3-Kinase Through the Protein Kinase PDK1

1998 • 1,118 citations

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1998 • 1,097 citations

Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

1998 • 1,050 citations

Phosphorylation and Activation of p70 ^s6k by PDK1

1998 • 835 citations

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1997 • 740 citations

Control of p70 S6 kinase by kinase activity of FRAP in vivo

1995 • 717 citations

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

1995 • 441 citations

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

1999 • 440 citations

The 70 kDa S6 Kinase Complexes with and Is Activated by the Rho Family G Proteins Cdc42 and Rac1

1996 • 293 citations

Intracellular signalling: PDK1 – a kinase at the hub of things

1999 • 221 citations

p70 S6 Kinase Is Regulated by Protein Kinase Cζ and Participates in a Phosphoinositide 3-Kinase-Regulated Signalling Complex

1999 • 181 citations

The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation

1999 • 154 citations

Protein Kinase Cζ Is a Negative Regulator of Protein Kinase B Activity

1999 • 127 citations

Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex

1999 • 107 citations

Atypical protein kinase Cλ binds and regulates p70 S6 kinase

1998 • 74 citations