Reassessment of the Roles of Integrase and the Central DNA Flap in Human Immunodeficiency Virus Type 1 Nuclear Import

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

1996 • 4,854 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

Integration of murine leukemia virus DNA depends on mitosis.

1993 • 931 citations

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

1992 • 917 citations

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

1994 • 845 citations

HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap

2000 • 831 citations

Real-Time Single-Molecule Imaging of the Infection Pathway of an Adeno-Associated Virus

2001 • 819 citations

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1993 • 810 citations

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

1994 • 798 citations

Human Immunodeficiency Virus Type 1 Spinoculation Enhances Infection through Virus Binding

2000 • 662 citations

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.

1992 • 604 citations

Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

1997 • 600 citations

Human immunodeficiency virus infection of cells arrested in the cell cycle.

1992 • 523 citations

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

1997 • 483 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes.

1991 • 358 citations

HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import

1997 • 340 citations

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

1998 • 332 citations

Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1

2001 • 321 citations

Characterization of Intracellular Reverse Transcription Complexes of Human Immunodeficiency Virus Type 1

2001 • 311 citations

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

1995 • 309 citations

Efficient HIV-1 replication can occur in the absence of the viral matrix protein

1998 • 236 citations

Viral Entry into the Nucleus

2000 • 220 citations

The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells

2000 • 217 citations

Cytoplasmic Recruitment of INI1 and PML on Incoming HIV Preintegration Complexes

2001 • 216 citations

HIV-1 Infection Requires a Functional Integrase NLS

2001 • 201 citations

Interaction of the Human Immunodeficiency Virus Type 1 Vpr Protein with the Nuclear Pore Complex

1998 • 175 citations

Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

1996 • 154 citations

CXCR4 as a Functional Coreceptor for Human Immunodeficiency Virus Type 1 Infection of Primary Macrophages

1998 • 150 citations

A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract

1991 • 148 citations

High-Efficiency Ligation and Recombination of DNA Fragments by Vertebrate Cells

1983 • 148 citations

Human Immunodeficiency Virus Type 1 Nef Functions at the Level of Virus Entry by Enhancing Cytoplasmic Delivery of Virions

2001 • 142 citations

HOW DO ANIMAL DNA VIRUSES GET TO THE NUCLEUS?

1998 • 131 citations

Nuclear Import of Human Immunodeficiency Virus Type-1 Preintegration Complexes

1999 • 113 citations

Nuclear Localization of Human Immunodeficiency Virus Type 1 Preintegration Complexes (PICs): V165A and R166A Are Pleiotropic Integrase Mutants Primarily Defective for Integration, Not PIC Nuclear Import

2002 • 95 citations

Cellular Distribution and Karyophilic Properties of Matrix, Integrase, and Vpr Proteins from the Human and Simian Immunodeficiency Viruses

2000 • 92 citations

The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells

2000 • 76 citations

Nuclear Localization of Human Immunodeficiency Virus Type 1 Integrase Expressed as a Fusion Protein with Green Fluorescent Protein

1999 • 71 citations

Accumulation and Intranuclear Distribution of Unintegrated Human Immunodeficiency Virus Type 1 DNA

2001 • 61 citations