The molecular chaperone hsp40 regulates the activity of P58 IPK , the cellular inhibitor of PKR

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1990 • 1,003 citations

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1993 • 802 citations

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1994 • 651 citations

Tetratrico peptide repeat interactions: to TPR or not to TPR?

1995 • 624 citations

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1992 • 543 citations

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70

1994 • 473 citations

The TPR snap helix: a novel protein repeat motif from mitosis to transcription

1991 • 452 citations

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.

1993 • 436 citations

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding.

1996 • 424 citations

Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase.

1996 • 322 citations

The Interferon-induced Double-Stranded RNA-Activated Protein Kinase Induces Apoptosis

1994 • 322 citations

Autophosphorylation of the protein kinase dependent on double-stranded RNA.

1987 • 301 citations

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation.

1984 • 282 citations

Role of the Protein Chaperone YDJ1 in Establishing Hsp90-Mediated Signal Transduction Pathways

1995 • 237 citations

Translational Control

2013 • 230 citations

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast.

1993 • 227 citations

Blockage of NF-κB Signaling by Selective Ablation of an mRNA target by 2-5A Antisense Chimeras

1994 • 217 citations

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system.

1991 • 207 citations

Purification and properties of the dnaJ replication protein of Escherichia coli.

1985 • 178 citations

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells.

1990 • 164 citations

The 58,000-Dalton Cellular Inhibitor of the Interferon-Induced Double-Stranded RNA-Activated Protein Kinase (PKR) Is a member of the Tetratricopeptide Repeat Family of Proteins

1994 • 162 citations

3T3 fibroblasts transfected with a cDNA for mitochondrial aspartate aminotransferase express plasma membrane fatty acid-binding protein and saturable fatty acid uptake.

1995 • 151 citations

Mutants of the RNA-Dependent Protein Kinase (PKR) Lacking Double-Stranded RNA Binding Domain I Can Act as Transdominant Inhibitors and Induce Malignant Transformation

1995 • 139 citations

Hormone-dependent Transactivation by the Human Androgen Receptor Is Regulated by a dnaJ Protein

1995 • 137 citations

Translational Control by Influenza Virus

1995 • 134 citations

The eIF-2α kinases: regulators of protein synthesis in starvation and stress

1994 • 130 citations

The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties.

1994 • 122 citations

Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase

1988 • 108 citations

Chaperone functions of the heat shock proteins associated with steroid receptors

1994 • 108 citations

A stress-inducible 40 kDa protein (hsp40): purification by modified two-dimensional gel electrophoresis and co-localization with hsc70(p73) in heat-shocked HeLa cells

1993 • 102 citations

Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase.

1992 • 101 citations

Adipocyte differentiation of 3T3-L1 cells involves augmented expression of a 43-kDa plasma membrane fatty acid-binding protein.

1992 • 98 citations

Interaction of the Interferon-Induced PKR Protein Kinase with Inhibitory Proteins P58^IPK and Vaccinia Virus K3L Is Mediated by Unique Domains: Implications for Kinase Regulation

1996 • 96 citations

Cloning of a cDNA for Heat-Shock Protein hsp40, a Human Homolog of Bacterial DnaJ

1993 • 95 citations

Evidence for the Association of the Heme-regulated eIF-2α Kinase with the 90-kDa Heat Shock Protein in Rabbit Reticulocyte Lysate in Situ

1989 • 87 citations

The P58 Cellular Inhibitor Complexes with the Interferon-induced, Double-stranded RNA-dependent Protein Kinase, PKR, to Regulate Its Autophosphorylation and Activity

1996 • 82 citations

Platelet-derived Growth Factor Signal Transduction through the Interferon-inducible Kinase PKR

1995 • 81 citations

Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5'-untranslated region.

1993 • 81 citations

Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant‐type p53

1995 • 68 citations

Biosynthesis of aspartate aminotransferases. Both the higher molecular weight precursor of mitochondrial aspartate aminotransferase and the cytosolic isoenzyme are synthesized on free polysomes.

1982 • 60 citations

Heat shock alters the composition of heteromeric steroid receptor complexes and enhances receptor activity in vivo

1992 • 59 citations

Functional Expression and RNA Binding Analysis of the Interferon-Induced, Double-Stranded RNA-Activated, 68,000-M_rProtein Kinase in a Cell-Free System

1991 • 56 citations

Isolation and Properties of a Liver Mitochondrial Precursor Protein to Aspartate Aminotransferase Expressed in Escherichia coli

1989 • 43 citations

Activation of the double‐stranded RNA‐dependent eIF‐2α kinase by cellular RNA from 3T3‐F442A cells

1991 • 41 citations

An Hsp60 related protein is associated with purified HIV and SIV

1994 • 38 citations

Cloning, expression, and cellular localization of the oncogenic 58-kDa inhibitor of the RNA-activated human and mouse protein kinase

1996 • 37 citations

Stress responses to viral infection

1994 • 34 citations

Cotranslocation and Colocalization of hsp40 (DnaJ) with hsp70 (DnaK) in Mammalian Cells.

1995 • 31 citations

Cellular Inhibitors of the Interferon-Induced, dsRNA-Activated Protein Kinase

1994 • 21 citations

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