BiP Binding Sequences in Antibodies

Protein folding in the cell

1992 • 4,138 citations

The biology of heat shock proteins and molecular chaperones

1994 • 1,203 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Immunoglobulin heavy chain binding protein

1983 • 849 citations

Peptide-binding specificity of the molecular chaperone BiP

1991 • 763 citations

Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 • 763 citations

Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP

1993 • 650 citations

Heat shock proteins: molecular chaperones of protein biogenesis

1993 • 598 citations

Heat‐shock proteins as molecular chaperones

1994 • 551 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

1994 • 430 citations

Renaturation, Purification and Characterization of Recombinant Fab-Fragments Produced in Escherichia coli

1991 • 385 citations

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein.

1987 • 343 citations

A mild procedure for solid phase peptide synthesis: use of fluorenylmethoxycarbonylamino-acids

1978 • 287 citations

Common and divergent peptide binding specificities of hsp70 molecular chaperones.

1994 • 283 citations

Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation

1977 • 273 citations

BiP (GRP78), an essential hsp70 resident protein in the endoplasmic reticulum

1994 • 227 citations

Interaction of BiP with newly synthesized immunoglobulin light chain molecules: cycles of sequential binding and release.

1992 • 187 citations

ATP utilization by rep protein in the catalytic separation of DNA strands at a replicating fork.

1978 • 174 citations

Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers

1993 • 158 citations

Alternatively folded states of an immunoglobulin

1991 • 155 citations

Interaction of GroE with an all-beta-protein.

1992 • 103 citations

Influence of protein disulfide isomerase (PDI) on antibody folding in vitro.

1994 • 91 citations

A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion.

1990 • 85 citations

BIP—A Heat Shock Protein Involved in Immunoglobulin Chain Assembly

1991 • 81 citations

Coordination of immunoglobulin chain folding and immunoglobulin chain assembly is essential for the formation of functional IgG

1995 • 80 citations

Prolyl isomerases catalyze antibody folding in vitro

1993 • 73 citations

Association of Antibody Chains at Different Stages of Folding: Prolyl Isomerization Occurs after Formation of Quaternary Structure

1995 • 68 citations

Structure of a human monoclonal antibody Fab fragment against gp41 of human immunodeficiency virus type 1.

1992 • 61 citations

Hsc70, immunoglobulin heavy chain binding protein, and Hsp90 differ in their ability to stimulate transport of precursor proteins into mammalian microsomes.

1993 • 59 citations

Enhanced transcription of the 78,000-dalton glucose-regulated protein (GRP78) gene and association of GRP78 with immunoglobulin light chains in a nonsecreting B-cell myeloma line (NS-1).

1989 • 54 citations

Association of transport-defective light chains with immunoglobulin heavy chain binding protein

1990 • 39 citations

Domain interactions stabilize the alternatively folded state of an antibody Fab fragment

1995 • 27 citations

Correlation between the stability of the GroEL-protein ligand complex and the release mechanism.

1994 • 24 citations

Characterization of a quaternary‐structured folding intermediate of an antibody Fab‐fragment

1995 • 21 citations