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N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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TH-17 cells in the circle of immunity and autoimmunity

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mTOR and cancer: insights into a complex relationship

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Epigenetic Control of the foxp3 Locus in Regulatory T Cells

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Foxp3-dependent programme of regulatory T-cell differentiation

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Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells

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A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

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All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

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Aire regulates negative selection of organ-specific T cells

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The Two TORCs and Akt

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Transforming Growth Factor-β Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent Mechanisms

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The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

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Selective Survival of Naturally Occurring Human CD4+CD25+Foxp3+ Regulatory T Cells Cultured with Rapamycin

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Favorably Tipping the Balance between Cytopathic and Regulatory T Cells to Create Transplantation Tolerance

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Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells

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Natural regulatory T cells and self-tolerance

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Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

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A Kinetic and Dynamic Analysis of Foxp3 Induced in T Cells by TGF-β

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Cutting Edge: Deficiency in the E3 Ubiquitin Ligase Cbl-b Results in a Multifunctional Defect in T Cell TGF-β Sensitivity In Vitro and In Vivo

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Protein kinase B (Akt) regulation and function in T lymphocytes

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LAT-mediated signaling in CD4+CD25+ regulatory T cell development

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The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice

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IL-2 and Related Cytokines Can Promote T Cell Survival by Activating AKT

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Peptide Specificity of Thymic Selection of CD4+CD25+ T Cells

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Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

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Role of TCR specificity in CD4⁺CD25⁺ regulatory T‐cell selection

2006 • 95 citations

Antagonistic Interactions between Ikaros and the Chromatin Remodeler Mi-2β Determine Silencer Activity and Cd4 Gene Expression

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Enhanced thymic selection of FoxP3 ⁺ regulatory T cells in the NOD mouse model of autoimmune diabetes

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‘Vive la Résistance!’ – the PI3K–Akt pathway can determine target sensitivity to regulatory T cell suppression

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The protooncogeneMYCcan break B cell tolerance

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