Hydrogen Peroxide Enhances Shedding of Type I Soluble Tumor Necrosis Factor Receptor from Pulmonary Epithelial Cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

1997 • 1,651 citations

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

1990 • 1,507 citations

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.

1996 • 1,132 citations

REDOX REGULATION OF CELLULAR ACTIVATION

1997 • 1,121 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

An essential role for free radicals and derived species in signal transduction

1997 • 909 citations

Oxidative Stress in Chronic Obstructive Pulmonary Disease

1997 • 851 citations

Metalloproteinase-mediated release of human Fas ligand.

1995 • 835 citations

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

1991 • 815 citations

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

1994 • 799 citations

Activation of protein kinase C by tyrosine phosphorylation in response to H ₂ O ₂

1997 • 610 citations

Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis

1990 • 581 citations

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.

1989 • 578 citations

Tumor necrosis factor.

1991 • 568 citations

High Bronchoalveolar Levels of Tumor Necrosis Factor and Its Inhibitors, Interleukin-1, Interferon, and Elastase, in Patients with Adult Respiratory Distress Syndrome after Trauma, Shock, or Sepsis

1992 • 522 citations

Cytokines of the Lung

1990 • 443 citations

Shedding of tumor necrosis factor receptors by activated human neutrophils.

1990 • 443 citations

Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses.

1988 • 441 citations

Inhibition of protein kinase C by calphostin C is light-dependent

1991 • 374 citations

Metalloprotease-Disintegrins: Links to Cell Adhesion and Cleavage of TNFα and Notch

1997 • 363 citations

Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis.

1987 • 348 citations

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

1990 • 335 citations

Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency.

1997 • 306 citations

TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation.

1995 • 293 citations

Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice

1994 • 287 citations

Analysis of <scp>RNA</scp> by Northern and Slot Blot Hybridization

2004 • 274 citations

Cellular Oxygen Toxicity

1996 • 260 citations

A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.

1995 • 254 citations

Isolation and characterization of a tumor necrosis factor binding protein from urine

1989 • 249 citations

Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia.

1992 • 238 citations

TUMOUR NECROSIS FACTOR IN BRONCHOPULMONARY SECRETIONS OF PATIENTS WITH ADULT RESPIRATORY DISTRESS SYNDROME

1989 • 202 citations

Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

1992 • 152 citations

Variation in serum levels of the soluble TNF receptors among healthy individuals.

1992 • 145 citations

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor.

1990 • 139 citations

A tumor necrosis factor binding protein is present in human biological fluids

1988 • 122 citations

Physiological enzymatic cleavage of leukocyte membrane molecules

1995 • 110 citations

LPS-induced sTNF-receptor release in vivo in a murine model. Investigation of the role of tumor necrosis factor, IL-1, leukemia inhibiting factor, and IFN-gamma.

1993 • 93 citations

Adherence of neutrophils induces release of soluble tumor necrosis factor receptor forms.

1994 • 64 citations

Soluble Tumor Necrosis Factor Receptors are Elevated in Relation to Severity of Congestive Heart Failure

1997 • 59 citations

High concentrations of soluble tumor necrosis factor receptors in ascites

1992 • 59 citations

Tumor necrosis factor receptors and cytocidal activity are down-regulated by activators of protein kinase C.

1988 • 58 citations

Prevention of autoimmune diabetes mellitus in NOD mice by transgenic expression of soluble tumor necrosis factor receptor p55

1997 • 58 citations

Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells

1991 • 54 citations

Protein kinase C, interleukin-1 beta, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells.

1996 • 41 citations

Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor forms.

1994 • 33 citations

Elevated Levels of Type II Soluble Tumor Necrosis Factor Receptors in the Bronchoalveolar Lavage Fluids of Patients with Sarcoidosis

1997 • 26 citations

Soluble TNF receptors (TNF-sR55 and TNF-sR75) in lung allograft recipients displaying cytomegalovirus pneumonitis.

1994 • 22 citations

Prostaglandin–E2Regulation of Tumor Necrosis Factor Receptor Release in Human Monocytic THP-1 Cells

1996 • 21 citations

Tumour necrosis factor receptor gene expression and shedding in human whole lung tissue and pulmonary epithelium

1996 • 20 citations

Inhibition of Sephadex-induced lung injury in the rat by Ro 45-2081, a tumor necrosis factor receptor fusion protein.

1996 • 17 citations

Deleted Work

1955 • 0 citations