Metalloproteinase-mediated release of human Fas ligand.

The Fas Death Factor

1995 • 4,070 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

Processing of tumour necrosis factor-α precursor by metalloproteinases

1994 • 1,200 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

1993 • 643 citations

Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

1994 • 607 citations

Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor

1994 • 571 citations

Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1993 • 468 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts.

1993 • 383 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

Fas and Fas Ligand: A Death Factor and Its Receptor

1994 • 354 citations

Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.

1994 • 294 citations

The Role of APO‐1‐Mediated Apoptosis in the Immune System

1994 • 242 citations

A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.

1995 • 234 citations

CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.

1992 • 220 citations

The Pathophysiology Of Tumor Necrosis Factors

1992 • 153 citations

Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene.

1989 • 141 citations

Fas‐mediated Cytotoxicity ‐ A New Immunoregulatory and Pathogenic Function of Thl CD4⁺ T Cells

1995 • 71 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis???

1990 • 43 citations

Human t lymphocytes express a member of the matrix metalloproteinase gene family

1994 • 27 citations