Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

The Hallmarks of Cancer

2000 • 27,569 citations

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Role for a bidentate ribonuclease in the initiation step of RNA interference

2001 • 4,804 citations

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

2002 • 4,334 citations

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

RNAi

2000 • 2,596 citations

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

2000 • 1,767 citations

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

2002 • 1,526 citations

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

2001 • 1,430 citations

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

2001 • 1,055 citations

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

2000 • 867 citations

Identification of essential genes in cultured mammalian cells using small interfering RNAs

2001 • 835 citations

Specific interference with gene function by double-stranded RNA in early mouse development

1999 • 719 citations

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

2002 • 716 citations

RNA interference—2001

2001 • 698 citations

Stable suppression of gene expression by RNAi in mammalian cells

2002 • 549 citations

RNA interference: genetic wand and genetic watchdog

2000 • 309 citations

Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos

2000 • 239 citations

Specific Double-Stranded RNA Interference in Undifferentiated Mouse Embryonic Stem Cells

2001 • 226 citations

A Short Primer on RNAi

2001 • 176 citations

Folding and trimerization of clathrin subunits at the triskelion hub

1992 • 157 citations

Deficient heme synthesis as the cause of noninducibility of hemoglobin synthesis in a friend erythroleukemia cell line

1979 • 109 citations

Regulation of ribonuclease III processing by double-helical sequence antideterminants

1997 • 92 citations

Escherichia coli Ribonuclease III: Affinity Purification of Hexahistidine-Tagged Enzyme and Assays for Substrate Binding and Cleavage

2001 • 57 citations

Alteration of clathrin light chain expression by transfection and gene disruption.

1993 • 30 citations