Role of IGF system of mitogens in the induction of fibroblast proliferation by keloid-derived keratinocytes in vitro

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Wound Healing--Aiming for Perfect Skin Regeneration

1997 • 4,630 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

The Effects of Insulin-Like Growth Factors on Tumorigenesis and Neoplastic Growth

2000 • 805 citations

On the Nature of Hypertrophic Scars and Keloids: A Review

1999 • 785 citations

Ternary complex factors: growth factor regulated transcriptional activators

1994 • 686 citations

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

1991 • 680 citations

The Insulin-Like Growth Factors

1993 • 647 citations

Insulin-like growth factor binding proteins and their role in controlling IGF actions

1997 • 510 citations

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition

1993 • 481 citations

Keloids and Hypertrophic Scars

1989 • 477 citations

The molecular basis of keloid and hypertrophic scar formation

1998 • 425 citations

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.

1988 • 424 citations

HYPERTROPHIC SCARS, KELOIDS, AND CONTRACTURES

1997 • 392 citations

The IRS-Signaling System: A Network of Docking Proteins That Mediate Insulin and Cytokine Action

1998 • 369 citations

Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells.

1993 • 317 citations

Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism

1999 • 288 citations

The IRS-signalling system during insulin and cytokine action

1997 • 280 citations

Biochemical Composition of the Connective Tissue in Keloids and Analysis of Collagen Metabolism in Keloid Fibroblast Cultures

1985 • 263 citations

Keloids: a review of the literature

1990 • 250 citations

Identification, Characterization, and Regulation of a Rat Complementary Deoxyribonucleic Acid which Encodes Insulin-Like Growth Factor-I*

1987 • 241 citations

The Keratinocyte handbook

1994 • 229 citations

Estradiol and Antiestrogens Regulate a Growth Inhibitory Insulin-like Growth Factor Binding Protein 3 Autocrine Loop in Human Breast Cancer Cells

1996 • 225 citations

Basics of Cutaneous Wound Repair

1993 • 214 citations

Insulin‐like growth factor (IGF)‐I rescues breast cancer cells from chemotherapy‐induced cell death – proliferative and anti‐apoptotic effects

1999 • 192 citations

Epidermal Growth Factor and Insulin-Like Growth Factor I Enhance Keratinocyte Migration

1993 • 187 citations

Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids

1982 • 176 citations

In vitro paracrine regulation of human keratinocyte growth by fibroblast‐derived insulin‐like growth factors

1992 • 156 citations

Keloids

1995 • 145 citations

Historical notes on the use of pressure in the treatment of hypertrophic scars or keloids

1993 • 136 citations

Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in a keloidlike manner

2002 • 129 citations

Insulin-like growth factor I rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells.

1987 • 125 citations

In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen.

1993 • 123 citations

Investigation of the Influence of Keloid-Derived Keratinocytes on Fibroblast Growth and Proliferation in Vitro

2001 • 108 citations

Altered cytokine production in black patients with keloids

1992 • 108 citations

The Possible Role of Mast Cells (Allergy) in the Production of Keloid and Hypertrophic Scarring

1987 • 105 citations

A Partial Catalog of Proteins Secreted by Epidermal Keratinocytes in Culture

1999 • 95 citations

Collagen and Mucopolysaccharides in the Hypertrophic Scar

1974 • 94 citations

Elevated Levels of Plasminogen Activator Inhibitor-1 May Account for the Altered Fibrinolysis by Keloid Fibroblasts

1996 • 91 citations

Tumor suppressor activity of the gene encoding mammary-derived growth inhibitor.

1995 • 90 citations

Overexpression of insulin-like growth factor-binding protein-2 results in increased tumorigenic potential in Y-1 adrenocortical tumor cells.

2000 • 89 citations

Overexpression of Insulin-Like Growth Factor-1 (IGF-I) Receptor and the Invasiveness of Cultured Keloid Fibroblasts

1999 • 79 citations

Keloid Fibroblasts Resist Ceramide-Induced Apoptosis by Overexpression of Insulin-Like Growth Factor I Receptor

2000 • 77 citations

The human burn wound as a primary source of interleukin-1 activity.

1986 • 71 citations

Immunologic associations of keloids.

1992 • 56 citations

Structure of the collagen nodule from hypertrophic scars and keloids.

1981 • 52 citations

Epidermis as a Secretory Tissue: An In Vitro Tissue Model to Study Keratinocyte Secretion

1994 • 48 citations

Does an IGF-binding protein (IGFBP) present in involuting rat mammary gland regulate apoptosis?

1995 • 48 citations

Studies on the immunologic aspects of keloids and hypertrophic scars

1982 • 33 citations

Identification of structural characteristics that contribute to a difference in antiapoptotic function between human insulin and insulin-like growth factor 1 receptors.

1998 • 29 citations

Insulin-Like Growth Factor-I (IGF-I)/IGF-I Receptor Axis and Increased Invasion Activity of Fibroblasts in Keloid

2000 • 26 citations

Plastic surgery: keloid and hypertrophic scar.

1986 • 2 citations