A Leishmania major Response Locus Identified by Interval-specific Congenic Mapping of a T Helper Type 2 Cell Bias-controlling Quantitative Trait Locus

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

2002 • 1,612 citations

The Regulation of Immunity to Leishmania Major

1995 • 1,265 citations

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.

1990 • 954 citations

Finding Genes That Underlie Complex Traits

2002 • 866 citations

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1996 • 734 citations

Role of NK1.1 ⁺ T Cells in a T _H 2 Response and in Immunoglobulin E Production

1995 • 508 citations

Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

2001 • 487 citations

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

2000 • 397 citations

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection.

1994 • 365 citations

Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation

1999 • 285 citations

The other side of the coin: The protective role of the TH2 cytokines

2001 • 202 citations

Serial Backcross Mapping of Multiple Loci Associated with Resistance to Leishmania major in Mice

1997 • 144 citations

Quantitative Trait Loci Controlling Allergen-Induced Airway Hyperresponsiveness in Inbred Mice

2000 • 142 citations

The Function Role of GATA-3 in Th1 and Th2 Differentiation

2003 • 138 citations

Leishmaniasis host response loci (lmr1–3) modify disease severity through a Th1/Th2-independent pathway

2003 • 130 citations

Regulation of T helper cell differentiation by STAT molecules

1998 • 107 citations

MHC Class II Transactivator Inhibits IL-4 Gene Transcription by Competing with NF-AT to Bind the Coactivator CREB Binding Protein (CBP)/p300

2000 • 107 citations

Genetic Regulation of Commitment to Interleukin 4 Production by a CD4+ T Cell–intrinsic Mechanism

1998 • 104 citations

Congenic mice: cutting tools for complex immune disorders

2003 • 99 citations

IL-4 secreted from individual naive CD4+ T cells acts in an autocrine manner to induce Th2 differentiation

2002 • 89 citations

Early IL-4 production by non-CD4+ cells at the site of antigen deposition predicts the development of a T helper 2 cell response to Schistosoma mansoni eggs.

1995 • 73 citations

HISTOCOMPATIBILITY GENES OF MICE. V. FIVE NEW HISTOCOMPATIBILITY LOCI IDENTIFIED BY CONGENIC RESISTANT LINES ON A C57BL/10 BACKGROUND

1965 • 60 citations

Purification and Characterization of a Novel Physiological Substrate for Calcineurin in Mammalian Cells

1998 • 57 citations

Susceptibility genes in the pathogenesis of murine lupus.

2002 • 56 citations

The IL-4 production capability of different strains of naive CD4+ T cells controls the direction of the Th cell response

2002 • 55 citations

Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSHβ gene

2002 • 32 citations

The production of two Th2 cytokines, interleukin-4 and interleukin-10, is controlled independently by locus Cypr1 and by loci Cypr2 and Cypr3 , respectively

1999 • 29 citations

Regulation of Immune Responses by E3 Ubiquitin-Protein Ligases

2001 • 11 citations