c-Rel regulation of the cell cycle in primary mouse B lymphocytes

CDK inhibitors: positive and negative regulators of G1-phase progression

1999 • 6,003 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

NF-κB: Ten Years After

1996 • 3,008 citations

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

1999 • 2,410 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

1998 • 2,096 citations

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1993 • 1,258 citations

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 • 1,184 citations

D-type cyclin-dependent kinase activity in mammalian cells.

1994 • 1,073 citations

Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes

1998 • 1,058 citations

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1993 • 1,047 citations

Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1

1999 • 1,028 citations

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1998 • 933 citations

Cyclin E-CDK2 is a regulator of p27Kip1.

1997 • 915 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

NF-κB Function in Growth Control: Regulation of Cyclin D1 Expression and G₀/G₁-to-S-Phase Transition

1999 • 777 citations

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

1995 • 740 citations

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1

1997 • 698 citations

Distinct roles for E2F proteins in cell growth control and apoptosis

1997 • 694 citations

Regulation of the cyclin E gene by transcription factor E2F1.

1995 • 634 citations

Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

1999 • 554 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

1994 • 493 citations

Phosphatidylinositol 3-Kinase Couples the Interleukin-2 Receptor to the Cell Cycle Regulator E2F

1997 • 411 citations

Regulation of cyclin E transcription by E2Fs and retinoblastoma protein.

1996 • 387 citations

STAT3 Is Required for the gp130-mediated Full Activation of the c-myc Gene

1999 • 383 citations

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site.

1995 • 363 citations

B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching.

1996 • 304 citations

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

1998 • 251 citations

B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells

1998 • 250 citations

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter.

1994 • 242 citations

Down-regulation of p27 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing

1999 • 231 citations

Differential Regulation of Retinoblastoma Tumor Suppressor Protein by G₁ Cyclin-Dependent Kinase Complexes In Vivo

2001 • 207 citations

c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function

1999 • 172 citations

E2F target genes and cell-cycle checkpoint control

1999 • 168 citations

Cell-Free Degradation of p27^kip1, a G₁ Cyclin-Dependent Kinase Inhibitor, Is Dependent on CDK2 Activity and the Proteasome

1999 • 166 citations

Monoclonal antibodies to murine CD40 define two distinct functional epitopes

1994 • 152 citations

Stat Proteins Control Lymphocyte Proliferation by Regulating p27^Kip1 Expression

1998 • 133 citations

c-Rel is essential for B lymphocyte survival and cell cycle progression

1998 • 131 citations

The transcription factor E2F-1 mediates the autoregulation of RB gene expression

1994 • 122 citations

p50–NF-κB Complexes Partially Compensate for the Absence of RelB: Severely Increased Pathology in p50−/−relB−/−Double-knockout Mice

1997 • 112 citations

Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes.

1996 • 110 citations

Antigen receptor signaling: integration of protein tyrosine kinase functions

1998 • 108 citations

Inducible nuclear expression of NF-kappa B in primary B cells stimulated through the surface Ig receptor.

1991 • 103 citations

c-Rel Is Required for the Protection of B Cells from Antigen Receptor-Mediated, But Not Fas-Mediated, Apoptosis

2001 • 71 citations

A Pivotal Role of Cyclin D3 and Cyclin-Dependent Kinase Inhibitor p27 in the Regulation of IL-2-, IL-4-, or IL-10-Mediated Human B Cell Proliferation

1998 • 67 citations

Characterization of the Mouse Cyclin D3 Gene: Exon/Intron Organization and Promoter Activity

1996 • 62 citations

Anchorage-Independent Transcription of the Cyclin A Gene Induced by the E7 Oncoprotein of Human Papillomavirus Type 16

1998 • 49 citations

Ubiquitin/Proteasome-dependent Degradation of D-type Cyclins Is Linked to Tumor Necrosis Factor-induced Cell Cycle Arrest

2002 • 45 citations

Modulation of the p27kip1 cyclin-dependent kinase inhibitor expression during IL-4-mediated human B cell activation.

1997 • 39 citations

The regulated expression of cell cycle-related proteins as B-lymphocytes enter and progress through the G1 cell cycle stage following delivery of complete versus partial activation stimuli

1996 • 31 citations

IL-2-Dependent Expression of Genes Involved in Cytoskeleton Organization, Oncogene Regulation, and Transcriptional Control

1999 • 27 citations

Modulation of E2F activity in primary mouse B cells following stimulation via surface IgM and CD40 receptors

1999 • 24 citations

The Expression of p18INK4 and p27kip1 Cyclin-Dependent Kinase Inhibitors Is Regulated Differently During Human B Cell Differentiation

2000 • 24 citations