The Expanded Biology of Serotonin

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

2013 • 3,921 citations

Valvular Heart Disease Associated with Fenfluramine–Phentermine

1997 • 1,595 citations

The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders

2007 • 1,400 citations

Long story short: the serotonin transporter in emotion regulation and social cognition

2007 • 997 citations

Neuroendocrine pharmacology of stress

2003 • 913 citations

Selective Serotonin-Reuptake Inhibitors and Risk of Persistent Pulmonary Hypertension of the Newborn

2006 • 873 citations

Valvular Heart Disease and the Use of Dopamine Agonists for Parkinson's Disease

2007 • 857 citations

Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies

2002 • 810 citations

Platelet-Derived Serotonin Mediates Liver Regeneration

2006 • 758 citations

H1-Histamine Receptor Affinity Predicts Short-Term Weight Gain for Typical and Atypical Antipsychotic Drugs

2003 • 758 citations

Dopamine Agonists and the Risk of Cardiac-Valve Regurgitation

2007 • 699 citations

Evidence for Possible Involvement of 5-HT _2B Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications

2000 • 668 citations

5-Hydroxytryptamine2 and 5-hydroxytryptamine1A receptors mediate opposing responses on membrane excitability in rat association cortex

1991 • 599 citations

The developmental origins of anxiety

2004 • 541 citations

SERUM VASOCONSTRICTOR (SEROTONIN)

1948 • 530 citations

Effects of Antidepressant Medication on Morbidity and Mortality in Depressed Patients After Myocardial Infarction

2005 • 514 citations

Multiple Serotonergic Brainstem Abnormalities in Sudden Infant Death Syndrome

2006 • 492 citations

Serotonylation of Small GTPases Is a Signal Transduction Pathway that Triggers Platelet α-Granule Release

2003 • 444 citations

Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension

2002 • 408 citations

Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine.

2000 • 403 citations

High-Speed Imaging Reveals Neurophysiological Links to Behavior in an Animal Model of Depression

2007 • 375 citations

Serotonin and Migraine: Biology and Clinical Implications

2007 • 316 citations

Defects in Breathing and Thermoregulation in Mice with Near-Complete Absence of Central Serotonin Neurons

2008 • 308 citations

5-Hydroxytryptamine receptors in the human cardiovascular system

2006 • 281 citations

3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) Induces Fenfluramine-Like Proliferative Actions on Human Cardiac Valvular Interstitial Cells in Vitro

2003 • 281 citations

Molecular Biology of Serotonin Receptors - Structure and Function at the Molecular Level

2002 • 269 citations

5-HT _4(a) Receptors Avert Opioid-Induced Breathing Depression Without Loss of Analgesia

2003 • 264 citations

Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors

2007 • 257 citations

REVIEW ARTICLE: Coated-platelets: an emerging component of the procoagulant response

2005 • 251 citations

Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders

2003 • 250 citations

Effect of Antidepressants and Their Relative Affinity for the Serotonin Transporter on the Risk of Myocardial Infarction

2003 • 246 citations

Serotonin Regulates Mammary Gland Development via an Autocrine-Paracrine Loop

2004 • 235 citations

Medullary Serotonergic Network Deficiency in the Sudden Infant Death Syndrome: Review of a 15-Year Study of a Single Dataset

2001 • 235 citations

Serotonin in Pain and Analgesia: Actions in the Periphery

2004 • 234 citations

Innovative approaches for the development of antidepressant drugs: Current and future strategies

2005 • 223 citations

SERUM VASOCONSTRICTOR (SEROTONIN)

1948 • 218 citations

Finding New Tricks For Old Drugs: An Efficient Route For Public-Sector Drug Discovery

2005 • 216 citations

Serotonin toxicity: a practical approach to diagnosis and treatment

2007 • 215 citations

Multiple Serotonin Receptors: Clinical and Experimental Aspects

1994 • 212 citations

A Double-blind Clinical Trial in Weight Control

1984 • 205 citations

Serotonin Transporter Inhibitors Protect against Hypoxic Pulmonary Hypertension

2003 • 201 citations

8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents

2004 • 187 citations

The pipeline and future of drug development in schizophrenia

2007 • 185 citations

5‐HYDROXYTRYPTAMINE IN THE CARDIOVASCULAR SYSTEM: FOCUS ON THE SEROTONIN TRANSPORTER (SERT)

2006 • 181 citations

Contributions of 5-HT2C receptors to multiple actions of central serotonin systems

2004 • 171 citations

Serotonin and the Orchestration of Energy Balance

2007 • 171 citations

Interactions between integrin αIIbβ3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans

2008 • 169 citations

Antidepressant Agents for the Treatment of Chronic Pain and Depression

2007 • 168 citations

Chemosensitivity of serotonergic neurons in the rostral ventral medulla

2001 • 168 citations

Serotonin and energy balance: molecular mechanisms and implications for type 2 diabetes

2007 • 142 citations

High Plasma Serotonin Levels in Primary Pulmonary Hypertension

2000 • 137 citations

Mammary gland homeostasis employs serotonergic regulation of epithelial tight junctions

2007 • 134 citations

The role of central 5‐hydroxytryptamine (5‐HT, serotonin) receptors in the control of micturition

2006 • 122 citations

Pharmacological aspects of anticancer drug-induced emesis with emphasis on serotonin release and vagal nerve activity

2003 • 120 citations

5-hydroxytryptamine in premature ejaculation: opportunities for therapeutic intervention

2006 • 117 citations

Signaling in the Chemosensory Systems

2006 • 114 citations

Transglutaminase-dependent RhoA Activation and Depletion by Serotonin in Vascular Smooth Muscle Cells

2006 • 113 citations

The serotonin receptors : from molecular pharmacology to human therapeutics

2006 • 97 citations

Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges

2007 • 96 citations

Serotonin and the neurobiology of the ejaculatory threshold

2006 • 92 citations

Pathophysiology of preeclampsia and the role of serotonin

2001 • 91 citations

Possible Association Between 3,4-Methylenedioxymethamphetamine Abuse and Valvular Heart Disease

2007 • 84 citations

Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure

2004 • 67 citations

The Risk of Postpartum Hemorrhage With Selective Serotonin Reuptake Inhibitors and Other Antidepressants

2008 • 66 citations

Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits

2008 • 62 citations

Functional Consequence of Serotonin/5-HT _2B Receptor Signaling in Heart

2003 • 58 citations

5-hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells

2001 • 57 citations

The role of 5-HT on the cardiovascular and renal systems and the clinical potential of 5-HT modulation

2003 • 55 citations

Serotonin: An inducer of collagenase in myometrial smooth muscle cells

1991 • 51 citations

Activity of the Serotonergic System During Isoflurane Anesthesia

2007 • 49 citations

Functions of serotonin in hypoxic pulmonary vascular remodeling

2007 • 48 citations

Depression and Heart Disease: Therapeutic Implications

2008 • 47 citations

Effects of treatment with a 5‐HT₄ receptor antagonist in heart failure

2006 • 40 citations

A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination

1984 • 40 citations

Functional reactivity of 5-HT receptors in human umbilical cord and maternal subcutaneous fat arteries after normotensive or pre-eclamptic pregnancy

2006 • 39 citations

Mouse Genetic Approaches to Feeding Regulation: Serotonin 5-HT_2C Receptor Mutant Mice

2003 • 35 citations

Chemical Neuroanatomy of 5-HT Receptor Subtypes in the Mammalian Brain

2006 • 32 citations

The Natural Mutation Encoding a C Terminus-Truncated 5-Hydroxytryptamine_2B Receptor Is a Gain of Proliferative Functions

2004 • 32 citations

Serotonergic gene inactivation in mice: models for anxiety and aggression?

2005 • 29 citations

Molecular and Cellular Mechanisms for the Polarized Sorting of Serotonin Receptors: Relevance for Genesis and Treatment of Psychosis

2004 • 27 citations

Atrial fibrillation in carcinoid heart disease

2006 • 24 citations

Increased 5‐HT contractile response in late pregnant rat myometrium is associated with a higher density of 5‐HT_2A receptors

2007 • 21 citations

Trials of New Antiarrhythmic Drugs for Maintenance of Sinus Rhythm in Patients with Atrial Fibrillation

2004 • 16 citations

Opioid-induced Respiratory Depression: Are 5-HT4a Receptor Agonists the Cure?

2004 • 11 citations

The ovarian and cervical regions of the rat uterus display a different contractile response to serotonin and prostaglandin F2α I. The estrous cycle

2000 • 10 citations

The treatment of urinary incontinence with Duloxetine

2008 • 9 citations

5-hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells

2001 • 8 citations

Can SSRIs reduce the risk of preeclampsia in pregnant, depressed patients?

2004 • 4 citations