Conformational stability of globular proteins

Stability of Protein Structure and Hydrophobic Interaction

1988 • 1,293 citations

Protein stability curves

1987 • 990 citations

Temperature dependence of the hydrophobic interaction in protein folding.

1986 • 865 citations

Disulphide bridges in globular proteins

1981 • 770 citations

Characterization of a Helical Protein Designed from First Principles

1988 • 533 citations

Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bonds.

1988 • 445 citations

A Chemical Approach to Protein Design—Template‐Assembled Synthetic Proteins (TASP)

1989 • 403 citations

Alternative packing arrangements in the hydrophobic core of λrepresser

1989 • 375 citations

Energetics of complementary side chain packing in a protein hydrophobic core

1989 • 346 citations

MUTATIONAL EFFECTS ON PROTEIN STABILITY

1989 • 311 citations

Protein structure:A Practical Approach

1990 • 281 citations

Mutant forms of staphylococcal nuclease with altered patterns of guanidine hydrochloride and urea denaturation

1986 • 275 citations

Cotranslational processing and protein turnover in eukaryotic cells

1988 • 201 citations

A new method for determining the heat capacity change for protein folding

1989 • 197 citations

Low-temperature unfolding of a mutant of phage T4 lysozyme. 1. Equilibrium studies

1989 • 157 citations

Cold denaturation of staphylococcal nuclease.

1988 • 147 citations

Nature of the charge distribution in proteins

1981 • 140 citations

Protein engineering of disulfide bonds in subtilisin BPN'

1989 • 139 citations

Probing the Determinants of Protein Folding and Stability with Amino Acid Substitutions

1989 • 133 citations

Ribonuclease T1 is stabilized by cation and anion binding

1988 • 115 citations

Crystal structure of guanosine-free ribonuclease T1, complexed with vanadate(V), suggests conformational change upon substrate binding

1989 • 102 citations

Dramatic thermostabilization of yeast iso-1-cytochrome c by an asparagine----isoleucine replacement at position 57.

1989 • 95 citations

Amino acid substitutions that increase the thermal stability of the λ Cro protein

1989 • 91 citations

LX.—Invertase: a contribution to the history of an enzyme or unorganised ferment

1890 • 85 citations

Conformational stability and mechanism of folding of ribonuclease T1

1989 • 81 citations

Conformational stability and activity of ribonuclease T1 and mutants

1989 • 75 citations

Effects of multiple replacements at a single position on the folding and stability of dihydrofolate reductase from Escherichia coli

1989 • 70 citations

Stability studies on derivatives of the bovine pancreatic trypsin inhibitor

1987 • 51 citations