Conformational stability and mechanism of folding of ribonuclease T1

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Protein Denaturation

1968 • 2,108 citations

Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl .alpha.-chymotrypsin using different denaturants

1988 • 1,568 citations

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

Theory for the folding and stability of globular proteins

1985 • 1,248 citations

Protein stability curves

1987 • 990 citations

Urea and Guanidine Hydrochloride Denaturation of Ribonuclease, Lysozyme, α-Chymotrypsin, and b-Lactoglobulin

1974 • 798 citations

The Stability of Globular Protein

1975 • 648 citations

Biochemical Applications of Differential Scanning Calorimetry

1987 • 592 citations

Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bonds.

1988 • 445 citations

Thermodynamics of protein denaturation. III. Denaturation of ribonuclease in water and in aqueous urea and aqueous ethanol mixtures

1967 • 422 citations

Cold denaturation of myoglobin

1986 • 408 citations

Solvent denaturation

1978 • 383 citations

Isothermal Unfolding of Globular Proteins in Aqueous Urea Solutions

1964 • 316 citations

Selective binding and solvent denaturation

1987 • 307 citations

Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. II. Dependence on denaturant concentration at 25°

1969 • 269 citations

Three-state denaturation of α-lactalbumin by guanidine hydrochloride

1976 • 249 citations

Residual structure in large fragments of staphylococcal nuclease: effects of amino acid substitutions

1989 • 234 citations

Genetic and structural analysis of the protein stability problem

1987 • 227 citations

Thermodynamics of the unfolding of β-lactoglobulin A in aqueous urea solutions between 5 and 55°

1968 • 222 citations

A new method for determining the heat capacity change for protein folding

1989 • 197 citations

Denaturation of Bovine Carbonic Anhydrase B by Guanidine Hydrochloride

1973 • 189 citations

Estimation of the free energy of stabilization of ribonuclease A, lysozyme, alpha-lactalbumin, and myoglobin.

1982 • 171 citations

Low-temperature unfolding of a mutant of phage T4 lysozyme. 2. Kinetic investigations

1989 • 161 citations

Three-dimensional structure of the ribonuclease T1 2'-GMP complex at 1.9-A resolution.

1988 • 160 citations

Low-temperature unfolding of a mutant of phage T4 lysozyme. 1. Equilibrium studies

1989 • 157 citations

Reversible thermal unfolding of thermostable phosphoglycerate kinase. Thermostability associated with mean zero enthalpy change

1977 • 153 citations

Stability mutants of staphylococcal nuclease: large compensating enthalpy-entropy changes for the reversible denaturation reaction

1988 • 149 citations

Cold denaturation of staphylococcal nuclease.

1988 • 147 citations

Equilibrium and kinetics of the unfolding of lysozyme (muramidase) by guanidine hydrochloride

1966 • 141 citations

Ribonucleases in Taka-Diastase: Properties, Chemical Nature, and Applications

1964 • 119 citations

Ribonuclease T1 is stabilized by cation and anion binding

1988 • 115 citations

Urea-induced unfolding of the .alpha. subunit of tryptophan synthase: evidence for a multistate process

1981 • 109 citations

Genetic Studies of Protein Stability and Mechanisms of Folding

1988 • 102 citations

Ionization-linked Changes in Protein Conformation. II. The N → R Transition in β-Lactoglobulin

1961 • 77 citations

Conformational stability and activity of ribonuclease T1 and mutants

1989 • 75 citations

Catalysis of proline isomerization during protein-folding reactions

1988 • 73 citations

Stabilization of an associated folding intermediate of bovine growth hormone by site-directed mutagenesis.

1988 • 64 citations

Refined X-Ray Structure of the Low pH Form of Ribonuclease T1-2'-Guanylic Acid Complex at 1.9 Å Resolution1

1988 • 61 citations

Ribonuclease T1, Structure and function.

1970 • 56 citations

Chymotrypsinogen family of proteins. XI. Heat-capacity changes accompanying reversible thermal unfolding of proteins

1971 • 33 citations

[30a] Ribonuclease T1 from Taka-Diastase

1967 • 28 citations

TECHNIQUES FOR MEASURING FLUORESCENCE AND PHOSPHORESCENCE OF BIOLOGICAL MATERIALS*

1968 • 25 citations

Denaturation of Bence Jones Proteins by Guanidine Hydrochloride*

1972 • 22 citations

The Thermodynamics of myoglobin stability effects of axial ligand

1982 • 19 citations

Spectroscopic Studies on the Configurational Structures of Ribonuclease T1

1970 • 18 citations

Purification of ribonuclease T1

1987 • 14 citations

Unfolding by Temperature and Guanidine Hydrochloride of Chicken Pancreatic Polypeptide

1986 • 9 citations