Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bonds.

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

Primer of biostatistics

1981 • 2,697 citations

[14]Determination and analysis of urea and guanidine hydrochloride denaturation curves

1986 • 2,265 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Intramolecular Reaction in Polycondensations. I. The Theory of Linear Systems

1950 • 1,354 citations

THE KINETICS OF FORMATION OF NATIVE RIBONUCLEASE DURING OXIDATION OF THE REDUCED POLYPEPTIDE CHAIN

1961 • 1,148 citations

Protein stability curves

1987 • 990 citations

Urea and Guanidine Hydrochloride Denaturation of Ribonuclease, Lysozyme, α-Chymotrypsin, and b-Lactoglobulin

1974 • 798 citations

Disulphide bridges in globular proteins

1981 • 770 citations

The Stability of Globular Protein

1975 • 648 citations

Theory of Elastic Mechanisms in Fibrous Proteins

1956 • 497 citations

THE THERMODYNAMIC STABILITY OF PROTEINS

1987 • 338 citations

Kinetic role of a meta-stable native-like two-disulphide species in the folding transition of bovine pancreatic trypsin inhibitor

1984 • 308 citations

In vivo formation and stability of engineered disulfide bonds in subtilisin.

1986 • 232 citations

Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond

1987 • 224 citations

The crystallographically determined structures of atypical strained disulfides engineered into subtilisin.

1986 • 182 citations

Estimation of the free energy of stabilization of ribonuclease A, lysozyme, alpha-lactalbumin, and myoglobin.

1982 • 171 citations

Disulfide bonds and thermal stability in T4 lysozyme.

1988 • 165 citations

An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of .lambda. repressor

1986 • 149 citations

An engineered disulfide bond in dihydrofolate reductase

1987 • 133 citations

Replacements of Pro ⁸⁶ in Phage T4 Lysozyme Extend an α-Helix But Do Not Alter Protein Stability

1988 • 131 citations

Statistical mechanics of noncovalent bonds in polyamino acids. VIII. Covalent loops in proteins

1965 • 130 citations

Influence of an extrinsic crosslink on the folding pathway of ribonuclease A. Conformational and thermodynamic analysis of crosslinked (7-lysine, 41-lysine)-ribonuclease A

1984 • 119 citations

Harnessing disulfide bonds using protein engineering

1987 • 116 citations

Ribonuclease T1 is stabilized by cation and anion binding

1988 • 115 citations

Conformations of intermediates in the folding of the pancreatic trypsin inhibitor

1987 • 96 citations

A comparison of the physical chemical properties of oxidized and reduced alkylated ribonuclease

1959 • 87 citations

Thermodynamics of protein cross-links

1978 • 85 citations

Kinetic analysis of the folding and unfolding of a mutant form of bovine pancreatic trypsin inhibitor lacking the cysteine-14 and -38 thiols

1988 • 84 citations

On the Non‐Essentiality of Two Specific Disulphide Bonds in Ribonuclease for its Biological Activity

1967 • 80 citations

The problem of the stability of globular proteins

1981 • 72 citations

Folding pathway of a circular form of bovine pancreatic trypsin inhibitor

1984 • 70 citations

The disulphide folding pathway of ribonuclease T1

1986 • 65 citations

Macrocyclization equilibriums of polypeptides

1977 • 58 citations

Circular dichroism, Raman spectroscopy, and gel filtration of trapped folding intermediates of ribonuclease

1981 • 57 citations

Ribonuclease T1, Structure and function.

1970 • 56 citations

Dissecting the roles of individual interactions in protein stability: Lessons from a circularized protein

1985 • 49 citations

Regeneration of ribonuclease A from the reduced protein. 2. Energetic analysis

1982 • 48 citations

Toward an understanding of the folding of ribonuclease A.

1987 • 42 citations

Restrained least-squares refinement of the crystal structure of the ribonuclease T₁*2'-guanylic acid complex at 1·9 Å resolution

1987 • 41 citations

An intramolecular crosslinkage of lysozyme. Formation of crosslinks between lysine-1 and histidine-15 with bis(bromoacetamide) derivatives by a two-stage reaction procedure and properties of the resulting derivatives

1985 • 37 citations

Influences of pH and substrate analogs on ribonuclease T1 fluorescence

1970 • 32 citations

Early steps in the refolding reaction of reduced ribonuclease A

1978 • 29 citations

[30a] Ribonuclease T1 from Taka-Diastase

1967 • 28 citations

Conformation of the Constant Fragment of the Immunoglobulin Light Chain: Effect of Cleavage of the Polypeptide Chain and the Disulfide Bond1

1987 • 24 citations

Conformation and stability of the constant fragment of the immunoglobulin light chain containing an intramolecular mercury bridge

1986 • 23 citations

The 2-A resolution structure of a thermostable ribonuclease A chemically cross-linked between lysine residues 7 and 41.

1985 • 21 citations

PREPARATION OF A TWO‐DISULFIDE BONDED ENZYMICALLY ACTIVE DERIVATIVE FROM HEN EGG LYSOZYME

1980 • 15 citations

Purification of ribonuclease T1

1987 • 14 citations

Fluorescence of the Tryptophyl Residues of the Constant Fragment of the Immunoglobulin Light Chain

1987 • 5 citations