The DNA Rearrangement That Generates the TRK-T3 Oncogene Involves a Novel Gene on Chromosome 3 Whose Product Has a Potential Coiled-Coil Domain

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Predicting Coiled Coils from Protein Sequences

1991 • 3,977 citations

Chromosomal translocations in human cancer

1994 • 1,551 citations

A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants

1993 • 1,456 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex

1992 • 964 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Mechanism of met oncogene activation

1986 • 551 citations

High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma.

1989 • 272 citations

Molecular Characterization of a Thyroid Tumor-Specific Transforming Sequence Formed by the Fusion of ret Tyrosine Kinase and the Regulatory Subunit RIα of Cyclic AMP-Dependent Protein Kinase A

1993 • 239 citations

The ret proto-oncogene is consistently expressed in human pheochromocytomas and thyroid medullary carcinomas.

1990 • 233 citations

TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas.

1992 • 228 citations

Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

1992 • 224 citations

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase.

1993 • 191 citations

The trk family of tyrosine protein kinase receptors

1991 • 170 citations

Alternating purine-pyrimidine tracts may promote chromosomal translocations seen in a variety of human lymphoid tumours.

1989 • 160 citations

The Z-DNA motif d(TG)30 promotes reception of information during gene conversion events while stimulating homologous recombination in human cells in culture.

1990 • 147 citations

Oncogenic activation of tyrosine kinases

1994 • 138 citations

Molecular and Biochemical Characterization of the Human trk Proto-Oncogene

1989 • 124 citations

Tpr, a large coiled coil protein whose amino terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear pore complex.

1994 • 114 citations

The human minisatellite consensus at breakpoints of oncogene translocations

1990 • 111 citations

Mechanisms of overlap formation in nonhomologous DNA end joining.

1994 • 105 citations

A Sequence Analysis of the Genomic Regions Involved in the Rearrangements between TPM3 and NTRK1 Genes Producing TRK Oncogenes in Papillary Thyroid Carcinomas

1995 • 103 citations

The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins.

1994 • 101 citations

Short direct repeats flanking deletions, and duplicating insertions in p53 gene in human cancers.

1993 • 85 citations

The two genes generating RET/PTC3 are localized in chromosomal band 10q11.2

1994 • 70 citations

Identification and biochemical characterization of p70TRK, product of the human TRK oncogene.

1987 • 55 citations

Cytogenetic and molecular genetic characterization of papillary thyroid carcinomas

1992 • 52 citations

Dimerization Mediated through a Leucine Zipper Activates the Oncogenic Potential of the met Receptor Tyrosine Kinase

1993 • 52 citations

The Z-DNA Motif d(TG)₃₀ Promotes Reception of Information during Gene Conversion Events while Stimulating Homologous Recombination in Human Cells in Culture

1990 • 49 citations

Characterization of the NTRK1 Genomic Region Involved in Chromosomal Rearrangements Generating TRK Oncogenes

1993 • 42 citations

Human TRK proto-oncogene maps to chromosome 1q32-q41.

1990 • 39 citations

Mechanisms of Overlap Formation in Nonhomologous DNA End Joining

1994 • 29 citations

The human tropomyosin gene involved in the generation of the TRK oncogene maps to chromosome 1q31.

1991 • 28 citations

Localization of the TRK proto-oncogene to human chromosome bands 1q23-1q24.

1991 • 24 citations

Expression of TRK-T1 oncogene induces differentiation of PC12 cells.

1993 • 18 citations

Guanine-rich (GGNNGG) elements at chromosomal breakpoints interact with a loop-forming, single-stranded DNA-binding protein.

1994 • 16 citations

Demonstration by in situ hybridization of ret proto-oncogene mRNA in developing placenta during mid-term of rat gestation.

1990 • 14 citations

RET/ptc and TRK Oncogenes in Papillary Thyroid Carcinoma

1993 • 4 citations