The trk family of tyrosine protein kinase receptors

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

The nerve growth factor: thirty-five years later.

1987 • 720 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1989 • 624 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Mechanism of met oncogene activation

1986 • 551 citations

Atrial natriuretic peptide clearance receptor. Complete sequence and functional expression of cDNA clones.

1988 • 479 citations

Oncogenes in solid human tumours

1982 • 467 citations

Gene Transfer and Molecular Cloning of the Human NGF Receptor

1986 • 447 citations

Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF)

1989 • 429 citations

Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1

1989 • 390 citations

Cell adhesion molecules in vertebrate neural development.

1988 • 386 citations

Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system

1990 • 375 citations

Diverse forms of a receptor for acidic and basic fibroblast growth factors.

1990 • 352 citations

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development.

1990 • 342 citations

The Drosophila gene torso encodes a putative receptor tyrosine kinase

1989 • 327 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

Diversity of the Immunoglobulin Gene Superfamily

1989 • 293 citations

High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma.

1989 • 272 citations

Sequence of contactin, a 130-kD glycoprotein concentrated in areas of interneuronal contact, defines a new member of the immunoglobulin supergene family in the nervous system

1988 • 258 citations

Molecular characteristics of nerve growth factor receptors on PC12 cells.

1985 • 200 citations

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue.

1990 • 198 citations

Molecular investigations on the high-affinity nerve growth factor receptor

1991 • 154 citations

Identification of a nerve growth factor receptor protein in sympathetic ganglia membranes by affinity labeling.

1981 • 133 citations

Induction by NGF of Meiotic Maturation of Xenopus Oocytes Expressing the trk Proto-Oncogene Product

1991 • 133 citations

Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a.

1990 • 84 citations

Human trk Oncogenes Activated by Point Mutation, In-Frame Deletion, and Duplication of the Tyrosine Kinase Domain

1990 • 73 citations

Activation of the receptor kinase domain of the trk oncogene by recombination with two different cellular sequences.

1988 • 73 citations

Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain.

1990 • 54 citations

Abnormalities of chromosome 1 in relation to human malignant diseases

1989 • 48 citations

Mechanism of activation of the human trk oncogene.

1989 • 44 citations

Human TRK proto-oncogene maps to chromosome 1q32-q41.

1990 • 39 citations

Activation of the trk oncogene by alternatively spliced muscle and non-muscle tropomyosin sequences.

1989 • 7 citations