Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

PCR protocols — A guide to methods and applications

1990 • 10,078 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

Molecular cloning of a new transforming gene from a chemically transformed human cell line

1984 • 966 citations

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

1990 • 949 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

1987 • 413 citations

High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma.

1989 • 272 citations

Differential expression of the normal and of the translocated human c-myc oncogenes in B cells.

1983 • 262 citations

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene.

1988 • 246 citations

Human ret proto-oncogene mapped to chromosome 10q11.2.

1989 • 189 citations

cDNA cloning and characterization of ret activated in a human papillary thyroid carcinoma cell line

1990 • 105 citations

Frequent occurrence of cytogenetic abnormalities in sporadic nonmedullary thyroid carcinoma

1990 • 97 citations

The oncogene associated with human papillary thyroid carcinoma (PTC) is assigned to chromosome 10 q11-q12 in the same region as multiple endocrine neoplasia type 2A (MEN2A).

1989 • 66 citations

Developmentally Regulated Expression of a Human "Finger"-Containing Gene Encoded by the 5′ Half of the ret Transforming Gene

1988 • 50 citations

Activation of the ret-II oncogene without a sequence encoding a transmembrane domain and transforming activity of two ret-II oncogene products differing in carboxy-termini due to alternative splicing.

1989 • 49 citations

Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice.

1990 • 45 citations

Megabase inversions in the human genome as physiological events

1990 • 42 citations

Refined localization to contiguous regions on chromosome 10q of the two genes (H4 and RET) that form the oncogenic sequence PTC.

1991 • 37 citations

Suppressors of the malignant phenotype.

1990 • 28 citations

Analysis by pulsed field gel electrophoresis reveals complex rearrangements in two MET alleles in a chemically-treated human cell line, MNNG-HOS.

1990 • 10 citations