MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell–Delivered S-TRAIL in Human Gliomas

MicroRNAs

2004 • 33,206 citations

The Hallmarks of Cancer

2000 • 27,569 citations

MicroRNA expression profiles classify human cancers

2005 • 9,457 citations

The biochemistry of apoptosis

2000 • 7,314 citations

Oncomirs — microRNAs with a role in cancer

2006 • 6,877 citations

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

2004 • 4,068 citations

Silencing of microRNAs in vivo with ‘antagomirs’

2005 • 3,846 citations

MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells

2005 • 2,530 citations

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

2006 • 2,006 citations

miR-21-mediated tumor growth

2006 • 1,569 citations

MicroRNA Expression in Zebrafish Embryonic Development

2005 • 1,544 citations

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

2005 • 1,421 citations

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

2004 • 1,306 citations

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

1998 • 991 citations

The role of apoptosis in cancer development and treatment response

2005 • 921 citations

A Cellular MicroRNA Mediates Antiviral Defense in Human Cells

2005 • 906 citations

Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes

2004 • 831 citations

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

2006 • 769 citations

In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes

2005 • 584 citations

Establishment and characterization of multipotent neural cell lines using retrovirus vector‐mediated oncogene transfer

1990 • 375 citations

LNA-modified oligonucleotides mediate specific inhibition of microRNA function

2006 • 368 citations

Strategies to determine the biological function of microRNAs

2006 • 243 citations

Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (trail) gene

2002 • 207 citations

In VivoTracking of Neural Progenitor Cell Migration to Glioblastomas

2003 • 199 citations

APO2 ligand: a novel lethal weapon against malignant glioma?

1998 • 193 citations

Adenoviral-Mediated Transfer of the TNF-Related Apoptosis-Inducing Ligand/Apo-2 Ligand Gene Induces Tumor Cell Apoptosis

2000 • 187 citations

Glioma therapy and real‐time imaging of neural precursor cell migration and tumor regression

2004 • 181 citations

In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides

2003 • 153 citations

mTOR Controls FLIP_S Translation and TRAIL Sensitivity in Glioblastoma Multiforme Cells

2005 • 152 citations

Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo

2003 • 132 citations

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis

2005 • 101 citations

Innovative nanotechnologies for the delivery of oligonucleotides and siRNA

2006 • 89 citations

Inducible Release of TRAIL Fusion Proteins from a Proapoptotic Form for Tumor Therapy

2004 • 85 citations

Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL

2007 • 76 citations

Mechanisms of tumor cell invasion and angiogenesis in the central nervous system

2003 • 42 citations

Recurrent glioblastoma multiforme: advances in treatment and promising drug candidates

2006 • 35 citations