Fas/FasL-dependent Apoptosis of Alveolar Cells after Lipopolysaccharide-induced Lung Injury in Mice

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.

1994 • 6,682 citations

The Fas Death Factor

1995 • 4,070 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

Macrophages and Polymorphonuclear Neutrophils in Lung Defense and Injury

1990 • 1,091 citations

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1994 • 1,073 citations

The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen.

1992 • 839 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Intact Epithelial Barrier Function Is Critical for the Resolution of Alveolar Edema in Humans

1990 • 588 citations

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 • 574 citations

Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome.

1996 • 517 citations

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.

1996 • 464 citations

Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance

1987 • 452 citations

Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.

1996 • 401 citations

Neutrophil Apoptosis in the Acute Respiratory Distress Syndrome

1997 • 394 citations

Differential responses of the endothelial and epithelial barriers of the lung in sheep to Escherichia coli endotoxin.

1991 • 341 citations

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1994 • 307 citations

Induction of Apoptosis and Pulmonary Fibrosis in Mice in Response to Ligation of Fas Antigen

1997 • 289 citations

Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice.

1997 • 274 citations

Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation.

1991 • 244 citations

Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation.

1995 • 240 citations

Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia.

1996 • 203 citations

Role of Alveolar Macrophages in Initiation and Regulation of Inflammation inPseudomonas aeruginosaPneumonia

1998 • 197 citations

Upregulation of Two Death Pathways of Perforin/Granzyme and FasL/Fas in Septic Acute Respiratory Distress Syndrome

2000 • 168 citations

The Involvement of Fas–Fas Ligand Pathway in Fibrosing Lung Diseases

1999 • 167 citations

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin.

1995 • 149 citations

Endothelial Cell Apoptosis in Lipopolysaccharide–Induced Lung Injury in Mice

1998 • 137 citations

Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue.

1993 • 104 citations

Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia

1996 • 78 citations

Lung to blood passage of different-sized molecules during lung inflammation in the rat

1991 • 34 citations