Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation.

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Peptide growth factors are multifunctional

1988 • 835 citations

IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice.

1989 • 578 citations

Acute Inflammation and Microthrombosis Induced by Endotoxin, Interleukin-1, and Tumor Necrosis Factor and their Implication in Gram-Negative Infection

1989 • 230 citations

Kinetics and mechanisms of recombinant human interleukin 1 and tumor necrosis factor-alpha-induced changes in circulating numbers of neutrophils and lymphocytes.

1987 • 229 citations

Structure of the Rat Interleukin 6 Gene and Its Expression in Macrophage-derived Cells

1989 • 199 citations

Inducible production of interleukin-6 by human polymorphonuclear neutrophils: role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha

1990 • 193 citations

The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammation.

1991 • 157 citations

Effect of cytokines on polymorphonuclear neutrophil infiltration in the mouse. Prostaglandin- and leukotriene-independent induction of infiltration by IL-1 and tumor necrosis factor.

1988 • 140 citations

Synergy Between Tumour Necrosis Factorα and Interleukin-1 in the Induction of Polymorphonuclear Leukocyte Migration During Inflammation

1988 • 116 citations

Antagonistic and agonistic effects of transforming growth factor-beta and IL-1 in rheumatoid synovium.

1990 • 112 citations

Endotoxin-induced cytokine gene expression in vivo. II. Regulation of tumor necrosis factor and interleukin-1 alpha/beta expression and suppression.

1990 • 109 citations

Detection by in situ hybridization and phenotypic characterization of cells expressing IL-6 mRNA in human stimulated blood.

1990 • 66 citations

Role of Interferon-γ in Counteracting the Suppressive Effects of Transforming Growth Factor-β2 and Glucocorticoids on the Production of Tumor Necrosis Factor-α

1990 • 44 citations