Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue.

Endotoxin and lung injury.

1986 • 679 citations

Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response

1992 • 459 citations

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor.

1985 • 394 citations

The intratracheal administration of endotoxin and cytokines. I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrate.

1991 • 303 citations

Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor alpha.

1990 • 290 citations

Cytokine-induced neutrophil-derived interleukin-8.

1992 • 260 citations

Compartmentalization of Intraalveolar and Systemic Lipopolysaccharide-Induced Tumor Necrosis Factor and the Pulmonary Inflammatory Response

1989 • 244 citations

Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1).

1992 • 224 citations

Inducible production of interleukin-6 by human polymorphonuclear neutrophils: role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha

1990 • 193 citations

Cachetin/TNF-α in Septic Shock and Septic Adult Respiratory Distress Syndrome

1988 • 183 citations

Pulmonary Fibroblast Expression of Interleukin-8: A Model for Alveolar Macrophage-derived Cytokine Networking

1991 • 153 citations

Release of tumor necrosis factor by human polymorphonuclear leukocytes

1990 • 144 citations

Differential Production of Tumor Necrosis Factor, Macrophage Colony Stimulating Factor, and Interleukin 1 by Human Alveolar Macrophages

1989 • 115 citations

Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF) Gene Expression by Eosinophils in Nasal Polyposis

1991 • 105 citations

Immunohistochemical demonstration of cytoplasmic and membrane-associated tumor necrosis factor in murine macrophages.

1988 • 101 citations

The Effect of Endotoxin Inhalation on Airway Responsiveness and Cellular Influx in Rats

1990 • 96 citations

Cytokine regulation of IL-1 beta gene expression in the human polymorphonuclear leukocyte.

1990 • 91 citations

Phagocytosis of Opsonized Yeast Induces Tumor Necrosis Factor-α mRNA Accumulation and Protein Release by Human Polymorphonuclear Leukocytes

1991 • 83 citations

Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute inflammation.

1992 • 81 citations

Lactoferrin release and interleukin-1, interleukin-6, and tumor necrosis factor production by human polymorphonuclear cells stimulated by various lipopolysaccharides: relationship to growth inhibition of Candida albicans

1992 • 64 citations

Activated Pulmonary Vascular Neutrophils as Early Mediators of Endotoxin-induced Lung Inflammation

1993 • 60 citations

Human Upper Airway Structural Cell-derived Cytokines Support Human Peripheral Blood Monocyte Survival: A Potential Mechanism for Monocyte/Macrophage Accumulation in the Tissue

1992 • 43 citations

Tumor necrosis factor and interleukin-1 activities in free lung cells after single and repeated inhalation of bacterial endotoxin

1991 • 33 citations

IL-1 beta and IL-6 gene expression in alveolar macrophages: modulation by extracellular matrices

1992 • 25 citations