Virulence factors of medically important fungi

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Bacterial Adherence: Adhesin-Receptor Interactions Mediating the Attachment of Bacteria to Mucosal Surfaces

1981 • 1,486 citations

Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

1995 • 1,170 citations

Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

1991 • 1,018 citations

Infections withCryptococcus neoformansin the Acquired Immunodeficiency Syndrome

1989 • 792 citations

Paracoccidioidomycosis: an update

1993 • 719 citations

Molecular Koch's Postulates Applied to Microbial Pathogenicity

1988 • 636 citations

PUTATIVE VIRULENCE FACTORS OF CANDIDA ALBICANS

1991 • 632 citations

Selective Protection against Conidia by Mononuclear and against Mycelia by Polymorphonuclear Phagocytes in Resistance to Aspergillus

1982 • 624 citations

Prognostic Factors in Cryptococcal Meningitis

1974 • 604 citations

Clinical and Host Differences Between Infections with the Two Varieties of Cryptococcus neoformans

1995 • 484 citations

Genetic association of mating types and virulence in Cryptococcus neoformans

1992 • 435 citations

Complementation of a Capsule-Deficient Mutation of Cryptococcus neoformans Restores its Virulence

1994 • 428 citations

The Ecology of Cryptococcus neoformans and the Epidemiology of Cryptococcosis

1991 • 424 citations

Cryptococcus neoformans melanin and virulence: mechanism of action

1995 • 401 citations

Adherence and receptor relationships of Candida albicans

1991 • 391 citations

Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase

1994 • 367 citations

Fungal infection in chronic granulomatous disease

1981 • 361 citations

Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans

1986 • 347 citations

Aflatoxins in food: Occurrence, biosynthesis, effects on organisms, detection, and methods of control

1991 • 337 citations

Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies.

1993 • 336 citations

Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice

1982 • 324 citations

Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide.

1985 • 320 citations

Polysaccharide antigens of the capsule of Cryptococcus neoformans

1994 • 315 citations

Activation of the adhesive capacity of CR3 on neutrophils by endotoxin: dependence on lipopolysaccharide binding protein and CD14.

1991 • 300 citations

Ecology, life cycle, and infectious propagule of Cryptococcus neoformans

1990 • 280 citations

DISTRIBUTION OF α AND α MATING TYPES OF CRYPTOCOCCUS NEOFORMANS AMONG NATURAL AND CLINICAL ISOLATES

1978 • 275 citations

Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants

1994 • 258 citations

In Vivo Bronchoalveolar Macrophage Defense Against Rhizopus oryzae and Aspergillus fumigatus

1984 • 254 citations

Experimental murine paracoccidiodomycosis induced by the inhalation of conidia

1987 • 252 citations

Estrogens inhibit mycelium-to-yeast transformation in the fungus Paracoccidioides brasiliensis: implications for resistance of females to paracoccidioidomycosis

1984 • 249 citations

Estimation of the Prevalence of Cryptococcal Infection Among Patients Infected with the Human Immunodeficiency Virus in New York City

1994 • 249 citations

The capsule of Cryptococcus neoformans passively inhibits phagocytosis of the yeast by macrophages

1983 • 245 citations

Protection of mice against experimental cryptococcosis by anti-Cryptococcus neoformans monoclonal antibody

1987 • 243 citations

Exocellular components of Paracoccidioides brasiliensis: identification of a specific antigen

1986 • 242 citations

rodletless mutants of Aspergillus fumigatus

1994 • 234 citations

Decreased susceptibility of melanized Cryptococcus neoformans to UV light

1994 • 226 citations

Correlation of elastase production by some strains of Aspergillus fumigatus with ability to cause pulmonary invasive aspergillosis in mice

1984 • 223 citations

A Rapid Colorimetric Assay of Fungal Viability with the Tetrazolium Salt MTT

1985 • 222 citations

Regulation of Cryptococcal Capsular Polysaccharide by Iron

1993 • 214 citations

Antioxidant function of fungal melanin

1993 • 214 citations

Idiopathic CD4+ T-Lymphocytopenia -- Four Patients with Opportunistic Infections and No Evidence of HIV Infection

1993 • 213 citations

Adhesins and ligands involved in the interaction of Candida spp. with epithelial and endothelial surfaces

1994 • 212 citations

Binding of Paracoccidioides brasiliensis to laminin through surface glycoprotein gp43 leads to enhancement of fungal pathogenesis

1994 • 212 citations

Specific susceptibility to mucormycosis in murine diabetes and bronchoalveolar macrophage defense against Rhizopus.

1984 • 211 citations

Hydrocortisone-enhanced growth of Aspergillus spp.: implications for pathogenesis

1994 • 210 citations

Damage to hyphal forms of fungi by human leukocytes in vitro. A possible host defense mechanism in aspergillosis and mucormycosis.

1978 • 209 citations

Aflatoxins in Animal and Human Health

1992 • 206 citations

Elastin Fragments Attract Macrophage Precursors to Diseased Sites in Pulmonary Emphysema

1981 • 205 citations

Immunological Unresponsiveness Induced by Cryptococcal Capsular Polysaccharide Assayed by the Hemolytic Plaque Technique

1972 • 205 citations

Factors Influencing Killing of Cryptococcus neoformans by Human Leukocytes In Vitro

1972 • 204 citations

Decreased virulence in stable, acapsular mutants ofCryptococcus neoformans

1982 • 203 citations

Histoplasma capsulatum modulates the acidification of phagolysosomes.

1993 • 197 citations

Capsular Polysaccharides of Cryptococcus neoformans

1984 • 196 citations

In Vitro Killing of Spores and Hyphae of Aspergillus fumigatus and Rhizopus oryzae by Rabbit Neutrophil Cationic Peptides and Bronchoalveolar Macrophages

1986 • 195 citations

Damage to Aspergillus fumigatus and Rhizopus oryzae Hyphae by Oxidative and Nonoxidative Microbicidal Products of Human Neutrophils In Vitro

1982 • 193 citations

Protective and nonprotective monoclonal antibodies to Cryptococcus neoformans originating from one B cell.

1995 • 191 citations

Evidence for possible involvement of an elastolytic serine protease in aspergillosis

1993 • 191 citations

Mycotoxins in foods and feeds in the United States

1992 • 186 citations

DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels.

1990 • 185 citations

Cryptococcus neoformans serotype A glucuronoxylomannan-protein conjugate vaccines: synthesis, characterization, and immunogenicity

1991 • 182 citations

Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes

1995 • 182 citations

Biochemical studies of phenoloxidase and utilization of catecholamines in Cryptococcus neoformans

1982 • 178 citations

Immunosuppression in vitro by a metabolite of a human pathogenic fungus.

1984 • 178 citations

Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans

1982 • 177 citations

In vivo immunosuppressive activity of gliotoxin, a metabolite produced by human pathogenic fungi

1994 • 173 citations

Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus. Implications for the immunopathogenesis of Aspergillus-related diseases.

1992 • 173 citations

Invasive Aspergillosis in Patients with AIDS

1994 • 169 citations

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

1994 • 169 citations

Deferoxamine augments growth and pathogenicity of Rhizopus, while hydroxypyridinone chelators have no effect

1994 • 165 citations

Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans.

1995 • 164 citations

Purification and characterization of an elastinolytic metalloprotease from Aspergillus fumigatus and immunoelectron microscopic evidence of secretion of this enzyme by the fungus invading the murine lung

1994 • 156 citations

Gliotoxin induces apoptosis in macrophages unrelated to its antiphagocytic properties.

1988 • 155 citations

Estradiol binds to a receptor-like cytosol binding protein and initiates a biological response in Paracoccidioides brasiliensis.

1983 • 151 citations

Molecular characterization of the humoral responses to Cryptococcus neoformans infection and glucuronoxylomannan-tetanus toxoid conjugate immunization.

1993 • 150 citations

Coccidioidomycosis: Factors Affecting the Host-Parasite Interaction

1983 • 150 citations

The alkaline protease of Aspergillus fumigatus is not a virulence determinant in two murine models of invasive pulmonary aspergillosis

1993 • 149 citations

Virulence of alkaline protease-deficient mutants ofAspergillus fumigatus

1993 • 145 citations

An Aspergillus fumigatus alkaline protease mutant constructed by gene disruption is deficient in extracellular elastase activity

1992 • 144 citations

Altered expression of surface alpha-1,3-glucan in genetically related strains of Blastomyces dermatitidis that differ in virulence

1994 • 142 citations

Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis.

1994 • 140 citations

Nonencapsulated Variant of Cryptococcus neoformans I. Virulence Studies and Characterization of Soluble Polysaccharide

1971 • 139 citations

The medically important dematiaceous fungi and their identification

1991 • 139 citations

The Genetic Basis of Chronic Granulomatous Disease

1994 • 139 citations

Mechanisms of Resistance of Aspergillus fumigatus Conidia to Killing by Neutrophils in Vitro

1985 • 136 citations

Identification of an Agent in Cultures of Aspergillus fumigatus Displaying Anti-phagocytic and Immunomodulating Activity in vitro

1985 • 130 citations

Inhibition by estrogens of conidium-to-yeast conversion in the fungus Paracoccidioides brasiliensis

1988 • 130 citations

The Respiratory Burst Oxidase and the Molecular Genetics of Chronic Granulomatous Disease

1993 • 130 citations

The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid

1993 • 128 citations

The WI-1 antigen of Blastomyces dermatitidis yeasts mediates binding to human macrophage CD11b/CD18 (CR3) and CD14.

1995 • 127 citations

Pathogenicity and virulence of wild-type and melanin-deficientWangiella dermatitidis

1987 • 126 citations

The effect of gliotoxin upon macrophage function

1986 • 125 citations

Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis

1994 • 125 citations

Complement Depletion in Cryptococcal Sepsis

1978 • 124 citations

Binding of Cryptococcus neoformans by human cultured macrophages. Requirements for multiple complement receptors and actin.

1991 • 118 citations

Killing of Cryptococcus neoformans strains by human neutrophils and monocytes

1991 • 118 citations

Reaction of superoxide anions with melanins: electron spin resonance and spin trapping studies

1986 • 117 citations

Cryptococcus neoformans: size range of infectious particles from aerosolized soil

1977 • 117 citations

Ingestion of acapsular Cryptococcus neoformans occurs via mannose and beta-glucan receptors, resulting in cytokine production and increased phagocytosis of the encapsulated form

1995 • 117 citations

The mouse antibody response to infection with Cryptococcus neoformans: VH and VL usage in polysaccharide binding antibodies.

1991 • 116 citations

Cell walls from avirulent variants of Histoplasma capsulatum lack alpha-(1,3)-glucan

1988 • 116 citations

The 18-kilodalton antigen secreted by Aspergillus fumigatus

1991 • 113 citations

New, special stain for histopathological diagnosis of cryptococcosis

1981 • 113 citations

Activation of C3 and binding to Aspergillus fumigatus conidia and hyphae

1989 • 113 citations

Purification and characterization of a fibrinogenolytic serine proteinase from Aspergillus fumigatus culture filtrate

1992 • 112 citations

Antioxidant function of melanin in black fungi

1995 • 112 citations

Role of the Capsule in Phagocytosis of Cryptococcus neoformans

1988 • 110 citations

Occurrences, immunoglobulin classes, and biological activities of antibodies in normal human serum that are reactive with Cryptococcus neoformans glucuronoxylomannan

1994 • 110 citations

Regulation of cell-mediated immunity in cryptococcosis. I. Induction of specific afferent T suppressor cells by cryptococcal antigen.

1982 • 110 citations

Genetic and phenotypic characterization of capsule mutants of Cryptococcus neoformans

1982 • 109 citations

Melanin as a virulence factor in pathogenic fungi

1990 • 108 citations

Identification of antigenic polypeptides ofParacoccidioides brasiliensisby immunoblotting

1989 • 106 citations

Virulence, serotype, and molecular characteristics of environmental strains of Cryptococcus neoformans var. gattii

1992 • 106 citations

Fungal Infections and Immune Responses

1993 • 105 citations

Paracoccidioides brasileensis: Cell wall structure and virulence

1977 • 105 citations

Effects of deferoxamine, feroxamine and iron on experimental mucormycosis (zygomycosis)

1989 • 104 citations

Enhancement of HIV-1 infection by the capsular polysaccharide of Cryptococcus neoformans

1992 • 104 citations

Monosaccharide and Chitin Content of Cell Walls of Histoplasma capsulatum and Blastomyces dermatitidis

1971 • 104 citations

Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients.

1990 • 104 citations

Activation of the complement system by Cryptococcus neoformans leads to binding of iC3b to the yeast

1986 • 104 citations

Effects of the two varieties of Cryptococcus neoformans cells and culture filtrate antigens on neutrophil locomotion

1995 • 104 citations

Iron limitation and the gamma interferon-mediated antihistoplasma state of murine macrophages

1991 • 104 citations

Human sex hormones stimulate the growth and maturation of Coccidioides immitis

1981 • 103 citations

Leishmanial phosphatase blocks neutrophil O-2 production.

1984 • 102 citations

Paracoccidioidomycosis and its etiologic agentParacoccidioides brasiliensis

1993 • 101 citations

Histoplasma variation and adaptive strategies for parasitism: new perspectives on histoplasmosis

1991 • 100 citations

Variation in the structure of glucuronoxylomannan in isolates from patients with recurrent cryptococcal meningitis

1995 • 100 citations

Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages

1994 • 99 citations

Catecholamines and virulence of Cryptococcus neoformans

1990 • 97 citations

Differential stimulation of murine resident peritoneal cells by selectively opsonized encapsulated and acapsular Cryptococcus neoformans

1988 • 95 citations

Comparison of Isolates of Sporothrix schenckii Obtained from Fixed Cutaneous Lesions with Isolates from Other Types of Lesions

1979 • 92 citations

Encapsulation of Cryptococcus neoformans impairs antigen-specific T-cell responses

1991 • 90 citations

Paradoxical role of capsule in murine bronchoalveolar macrophage-mediated killing of Cryptococcus neoformans.

1989 • 90 citations

An Estrogen-Binding Protein and Endogenous Ligand in Saccharomyces cerevisiae : Possible Hormone Receptor System

1982 • 89 citations

Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans

1994 • 89 citations

Recognition between Candida albicans and host cells

1993 • 89 citations

Epidemiologic aspects of blastomycosis, the enigmatic systemic mycosis.

1986 • 89 citations

Production of the hexitol D-mannitol by Cryptococcus neoformans in vitro and in rabbits with experimental meningitis

1990 • 88 citations

Mucormycosis: association with deferoxamine therapy

1989 • 88 citations

Catecholamine uptake, melanization, and oxygen toxicity in Cryptococcus neoformans

1991 • 88 citations

Elastase production in clinical isolates of Aspergillus

1988 • 88 citations

Interactions between conidia of Aspergillus fumigatus and human complement component C3

1992 • 86 citations

Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans

1991 • 85 citations

Growth inhibition of Cryptococcus neoformans by cultured human monocytes: role of the capsule, opsonins, the culture surface, and cytokines

1990 • 83 citations

Roles of macrophage Fc and C3b receptors in phagocytosis of immunologically coated Cryptococcus neoformans.

1981 • 83 citations

Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections

1991 • 83 citations

Phylogenetic Spectrum of Fungi That Are Pathogenic to Humans

1994 • 82 citations

Phagosome-Lysosome Fusion in P388D1 Macrophages Infected With Histoplasma capsulatum

1988 • 81 citations

Mouse-human immunoglobulin G1 chimeric antibodies with activities against Cryptococcus neoformans

1994 • 79 citations

Specific interaction of Aspergillus fumigatus with fibrinogen and its role in cell adhesion

1994 • 79 citations

Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line

1995 • 79 citations

The effect of temperature on sporotrichosis

1963 • 78 citations

Estradiol-binding proteins from mycelial and yeast-form cultures of Paracoccidioides brasiliensis

1986 • 76 citations

Ingestion of yeast forms of Sporothrix schenckii by mouse peritoneal macrophages

1983 • 76 citations

A Multistate Outbreak of Sporotrichosis associated with Sphagnum Moss

1992 • 76 citations

Participation of Complement in the Phagocytosis of the Conidia of Aspergillus fumigatus by Human Polymorphonuclear Cells

1992 • 75 citations

Effects of strain variation, serotype, and structural modification on kinetics for activation and binding of C3 to Cryptococcus neoformans

1993 • 75 citations

Isolation and characterization of spontaneous avirulent variants of Histoplasma capsulatum

1987 • 74 citations

Virulence of Paracoccidioides brasiliensis: The influence of in vitro passage and storage

1990 • 74 citations

Fungal cell adhesion molecules in Candida albicans

1991 • 74 citations

Characterization of a unique corticosterone-binding protein in Candida albicans.

1982 • 74 citations

HYP1, a hydrophobin gene from Aspergillus fumigatus, complements the rodletless phenotype in Aspergillus nidulans

1994 • 72 citations

The 43-kDa glycoprotein from the human pathogen Paracoccidioides brasiliensis and its deglycosylated form: Excretion and susceptibility to proteolysis

1991 • 72 citations

Relationship of progesterone- and estradiol-binding proteins in Coccidioides immitis to coccidioidal dissemination in pregnancy

1983 • 72 citations

Disseminated Penicillium marneffei infection associated with human immunodeficiency virus: a report of two cases and a review of 35 published cases.

1993 • 72 citations

Adherence ofCandida albicansto host cells

1995 • 70 citations

Influence of Cryptococcal Antigens on Cell-Mediated Immunity

1988 • 68 citations

Influence of Fungal Surface Components on the Interaction of Coccidioides immitis with Polymorphonuclear Neutrophils

1986 • 67 citations

Expression of inducible nitric oxide synthase by stimulated macrophages correlates with their antihistoplasma activity

1994 • 67 citations

Inhibition of Complement by Culture Supernatants of Aspergillus fumigatus

1986 • 66 citations

Inhibition of Monocyte-Mediated Damage to Fungal Hyphae by Steroid Hormones

1983 • 66 citations

Gamma interferon cooperates with lipopolysaccharide to activate mouse splenic macrophages to an antihistoplasma state

1993 • 65 citations

Isolation of a mycotoxin (gliotoxin) from a bovine udder infected withAspergillus fumigatus

1989 • 65 citations

Recombinant murine gamma interferon stimulates macrophages of the RAW cell line to inhibit intracellular growth of Histoplasma capsulatum

1994 • 64 citations

Neutrophil chemotactic responses induced by fresh and swollen Rhizopus oryzae spores and Aspergillus fumigatus conidia

1985 • 64 citations

Extracellular proteolytic activity ofCryptococcus neoformans

1994 • 64 citations

Alterations in the pathogenicity of oneParacoccidioides brasiliensis isolate do not correlative with itsin vitro growth

1990 • 63 citations

Autonomous replication of foreign DNA in Histoplasma capsulatum: role of native telomeric sequences

1993 • 62 citations

Clustering of ligand on the surface of a particle enhances adhesion to receptor-bearing cells.

1988 • 62 citations

Resistance of spores of Aspergillus fumigatus to ingestion by phagocytic cells.

1987 • 62 citations

Involvement of cell wall glucans in the genesis and persistence of the inflammatory reaction caused by the fungus Paracoccidioides brasiliensis

1994 • 62 citations

Effect of Degree of Encapsulation upon Virulence of Cryptococcus Neoformans.

1959 • 62 citations

Interaction between Aspergillus fumigatus and basement membrane laminin: Binding and substrate degradation

1993 • 62 citations

Isolation and characterization of an elastinolytic proteinase from Aspergillus flavus

1990 • 62 citations

In vivo generation of linear plasmids with addition of telomeric sequences by Histoplasma capsulatum

1992 • 62 citations

Specific binding of human fibrinogen fragment D to Aspergillus fumigatus conidia

1992 • 61 citations

Genomic Cloning, Characterization, and Functional Analysis of the Major Surface Adhesin WI-1 on Blastomyces dermatitidis Yeasts

1995 • 61 citations

Effects of iron and desferrioxamine on Rhizopus infection

1990 • 60 citations

Isolation and characterization of an extracellular proteinase of Coccidioides immitis

1987 • 60 citations

Immunologic recognition of a 25-amino acid repeat arrayed in tandem on a major antigen of Blastomyces dermatitidis.

1993 • 59 citations

Isolation and properties of extracellular proteinases from Sporothrix schenckii

1987 • 59 citations

Temperature regulation of the cryptococcal phenoloxidase

1991 • 59 citations

Cell Wall Composition of Two Strains of Blastomyces dermatitidis Exhibiting Differences in Virulence for Mice

1972 • 58 citations

Molecular cloning and sequencing of the cDNA and gene for a novel elastinolytic metalloproteinase from Aspergillus fumigatus and its expression in Escherichia coli

1994 • 58 citations

The coccidioidal complement fixation and immunodiffusion-complement fixation antigen is a chitinase

1992 • 58 citations

Suppression of host defences by Aspergillus fumigatus.

1987 • 58 citations

Tumour necrosis factor productionin vivoandin vitroin response toParacoccidioides brasiliensisand the cell wall fractions thereof

1993 • 57 citations

Recombinant expression and antigenic properties of a 32-kilodalton extracellular alkaline protease, representing a possible virulence factor from Aspergillus fumigatus

1994 • 57 citations

Melanized and non‐melanized multicellular form mutants of Wangiella dermatitidis in mice: mortality and histopathology studies

1992 • 57 citations

Human Neutrophil Degranulation Stimulated by Aspergillus fumigatus

1990 • 56 citations

Killing of Cryptococcus neoformans by Human Peripheral Blood Mononuclear Cells Stimulated in Culture

1991 • 55 citations

LIPID CONTENT OF FOUR STRAINS OF BLASTOMYCES DERMATITIDIS OF DIFFERENT MOUSE VIRULENCE

1963 • 54 citations

Isolation, characterization, and cloning of cDNA and the gene for an elastinolytic serine proteinase from Aspergillus flavus

1994 • 54 citations

The immunomodulating agent gliotoxin causes genomic DNA fragmentation

1987 • 54 citations

Identification of the 33-kDa alkaline protease of Aspergillus fumigatus in vitro and in vivo

1993 • 53 citations

Strain variation in antiphagocytic activity of capsular polysaccharides from Cryptococcus neoformans serotype A

1989 • 53 citations

Potentiation of interferon-mediated inhibition of Chlamydia infection by interleukin-1 in human macrophage cultures

1995 • 53 citations

Detection of two Blastomyces dermatitidis serotypes by exoantigen analysis

1983 • 52 citations

Cryptococcal capsular polysaccharide-induced modulation of murine immune responses

1982 • 52 citations

Melanin-deficient mutants ofCryptococcus neoformans

1994 • 52 citations

Aspergillus fumigatus complement inhibitor: production, characterization, and purification by hydrophobic interaction and thin-layer chromatography

1990 • 50 citations

Virulence studies of Aspergillus nidulans mutants requiring lysine or p-aminobenzoic acid in invasive pulmonary aspergillosis

1994 • 49 citations

Macrophage-Cryptococcus interactions.

1994 • 49 citations

Lack of vessel wall elastolysis in human invasive pulmonary aspergillosis

1992 • 47 citations

Purification and characterization of the major antigen WI-1 from Blastomyces dermatitidis yeasts and immunological comparison with A antigen

1994 • 47 citations

Proteinase production by the parasitic cycle of the pathogenic fungus Coccidioides immitis

1987 • 47 citations

A comparative histopathological, immunological, and biochemical study of experimental intravenous paracoccidioidomycosis induced in mice by threeParacoccidioides brasiliensisisolates

1986 • 46 citations

Construction and pathogenicity of Aspergillus fumigatus mutants that do not produce the ribotoxin restrictocin

1993 • 45 citations

Digestion of Histoplasma capsulatum yeasts by human macrophages.

1992 • 45 citations

A seroreactive 120-kilodalton beta-1,3-glucanase of Coccidioides immitis which may participate in spherule morphogenesis

1992 • 45 citations

Phagocytosis and Killing of Cryptococcus neoformans by Rat Alveolar Macrophages in the Absence of Serum

1989 • 45 citations

Spontaneous mutant ofBlastomyces dermatitidisattenuated in virulence for mice

1982 • 44 citations

A transformant ofAspergillus fumigatusdeficient in the antigenic cytotoxin ASPFI

1993 • 44 citations

Infection of P388D1 macrophages and respiratory epithelial cells by Histoplasma capsulatum: selection of avirulent variants and their potential role in persistent histoplasmosis

1991 • 43 citations

Virulence of Aspergillus fumigatus strains investigated by random amplified polymorphic DNA analysis

1995 • 42 citations

Enhancement of HIV Type 1 Infectivityin Vitroby Capsular Polysaccharide ofCryptococcus neoformansandHaemophilus influenzae

1994 • 41 citations

Human Immunodeficiency Virus (HIV)-Infected Human Blood Monocytes and Peritoneal Macrophages Have Reduced Anticryptococcal Activity whereas HIV-Infected Alveolar Macrophages Retain Normal Activity

1994 • 40 citations

Differences in cryptococcus neoformans capsular polysaccharide structure influence assembly of alternative complement pathway C3 convertase on fungal surfaces

1991 • 40 citations

WI-1, a novel 120-kilodalton surface protein on Blastomyces dermatitidis yeast cells, is a target antigen of cell-mediated immunity in human blastomycosis

1992 • 40 citations

Enzymatic degradation of the walls of spherules ofCoccidioides immitis

1982 • 40 citations

Chronic pulmonary and disseminated paracoccidioidomycosis in mice: quantitation of progression and chronicity

1987 • 39 citations

Utilization of indole compounds by Cryptococcus neoformans to produce a melanin-like pigment

1983 • 38 citations

Influence of Oestradiol on Protein Expression and Methionine Utilization during Morphogenesis of Paracoccidioides brasiliensis

1989 • 37 citations

Conditional virulence of a p-aminobenzoic acid-requiring mutant of Aspergillus fumigatus

1976 • 37 citations

Mel^-mutants ofWangiella dermatitidisin mice: evaluation of multiple mouse and fungal strains

1989 • 36 citations

Induction of a macrophage-suppressive lymphokine by soluble cryptococcal antigens and its association with models of immunologic tolerance

1987 • 36 citations

Isolation of antigens with proteolytic activity from Coccidioides immitis

1989 • 36 citations

Virulence of fungi: correlation of virulence of Blastomyces dermatitidis in vivo with escape from macrophage inhibition of replication in vitro

1981 • 36 citations

Genetic study of oxygen resistance and melanization in Cryptococcus neoformans

1994 • 35 citations

AIDS and the lung: update 1995. 1. Pneumocystis carinii pneumonia.

1995 • 35 citations

Altered expression of surface protein WI-1 in genetically related strains of Blastomyces dermatitidis that differ in virulence regulates recognition of yeasts by human macrophages

1994 • 35 citations

Changes in membrane fluidity modulate heat shock gene expression and produced attenuated strains in the dimorphic fungus Histoplasma capsulatum.

1993 • 35 citations

Morphological transition in the human fungal pathogen Histoplasma capulatum

1994 • 34 citations

An immunoreactive, water-soluble conidial wall fraction of Coccidioides immitis

1987 • 33 citations

Inhibition of Different Phases of Coccidioides immitis by Human Neutrophils or Hydrogen Peroxide

1986 • 33 citations

A Paracoccidioides brasiliensis Polysaccharide Having Granuloma-inducing, Toxic and Macrophage-stimulating Activity

1985 • 32 citations

Effect of Hypertonic Solutes Upon the Polysaccharide Capsule in Cryptococcus neoformans

1989 • 31 citations

Transforming DNA integrates at multiple sites in the dimorphic fungal pathogen Blastomyces dermatitidis

1997 • 31 citations

The role of fractions from Paracoccidioides brasiliensis in the genesis of inflammatory response

1987 • 30 citations

Characterization of a Phenol Oxidase from Cryptococcus neoformans var. neoformans

1993 • 30 citations

Cerebral mucormycosis in diabetic mice after intrasinus challenge

1984 • 30 citations

The interface of mycology and endocrinology

1989 • 29 citations

In vivo complement activation and binding of C3 to encapsulated Cryptococcus neoformans

1992 • 29 citations

Coccidioides immitis fractions which are antigenic for immune T lymphocytes

1991 • 29 citations

Acid Phosphatases of Sporothrix schenckii

1986 • 29 citations

Macrophage interactions with Candida.

1994 • 28 citations

Pathogen factors and host factors in murine pulmonary blastomycosis

1982 • 28 citations

Isolation and wall analysis of dimorphic mutants ofParacoccidioides brasiliensis

1982 • 28 citations

Influence of culture medium pH and proteinase inhibitors on extracellular proteinase activity and cell growth of Sporothrix schenckii

1988 • 27 citations

T-cell-dependent and T-cell-independent mechanisms of tolerance to glucuronoxylomannan of Cryptococcus neoformans serotype A

1993 • 25 citations

Regulation of mannitol biosynthesis and degradation by Cryptococcus neoformans

1994 • 25 citations

Western immunoblot analysis and serologic characterization of Blastomyces dermatitidis yeast form extracellular antigens

1992 • 25 citations

Isolation and expression of a gene which encodes a wall-associated proteinase of Coccidioides immitis

1992 • 25 citations

Heterogeneity of phenol oxidases in Cryptococcus neoformans

1992 • 25 citations

The Effect of Infection with Human Immunodeficiency Virus on the Anticryptococcal Activity of Lymphocytes and Monocytes

1995 • 24 citations

In vitro susceptibility of Cryptococcus neoformans to steroids.

1972 • 24 citations

The Discovery of Melanin Production in Cryptococcus neoformans and its Impact on Diagnosis and the Study of Virulence

1991 • 22 citations

Identification of a high-affinity binder for estradiol and a low-affinity binder for testosterone in Coccidioides immitis

1984 • 22 citations

Ultrastructural studies on the dimorphism ofParacoccidioides brasiliensis, Blastomyces dermatitidis and Histoplasma capsulatum

1981 • 22 citations

Iron assimilation inCryptococcus neoformans

1992 • 22 citations

The effect of elastase-specific monoclonal and polyclonal antibodies on the virulence ofAspergillus fumigatus in immunocompromised mice

1994 • 21 citations

Effects of hyperthermia on phagocytosis and intracellular killing of Sporothrix schenckii by polymorphonuclear leukocytes

1986 • 21 citations

MUCORMYCOSIS IN DIABETIC KETOACIDOSIS: Role of Unbound Iron Binding Capacity of Transferrin

1986 • 21 citations

Possible role of a proteinase in endosporulation of Coccidioides immitis

1988 • 21 citations

Expression inEscherichia coli of a gene coding for epitopes of a diagnostic antigen ofParacoccidioides brasiliensis

1989 • 20 citations

Antibody raised against extracellular proteinases ofSporothrix schenckii inS. schenkii inoculated hairless mice

1993 • 20 citations

Iron acquisition byCryptococcus neoformans

1995 • 20 citations

Enhancement of HIV-1 replication in peripheral blood mononuclear cells by Cryptococcus neoformans is monocyte-dependent but tumour necrosis factor-independent

1994 • 19 citations

Mechanisms of fungal pathogenicity: correlation of virulence in vivo, susceptibility to killing by polymorphonuclear neutrophils in vitro, and neutrophil superoxide anion induction among Blastomyces dermatitidis isolates

1991 • 19 citations

Molecular pathogenesis of fungal infections

1994 • 19 citations

Histologic Reactions to Cell Walls of an Avirulent and a Virulent Strain of Blastomyces dermatitidis

1974 • 18 citations

Growth temperatures of isolates of Sporothrix schenckii from disseminated and fixed cutaneous lesions of sporotrichosis

1986 • 17 citations

Pulmonary Infections and Immunity

1994 • 17 citations

Ultrastructure and cell wall chemistry of a thermosensitive mutant ofParacoccidioides brasiliensis

1983 • 17 citations

Effect of ferrioxarnine on the growth of Rhizopus

1993 • 16 citations

Sex hormones and susceptibility of the rat to paracoccidioidomycosis

1984 • 15 citations

Cytochemical localization of acid phosphatases in the dimorphic fungusSporothrix schenckii

1983 • 15 citations

Antigenic variability of Candida albicans cell surface.

1993 • 14 citations

Characterization of a proteinase inhibitor isolated from the fungal pathogen Coccidioides immitis

1989 • 13 citations

Effects of proteinase inhibitors on the cutaneous lesion ofSporothrix schenckii inoculated hairless mice

1993 • 13 citations

Studies on the relationship between paracoccidioidomycosis in ddY mice and their estrous cycle

1991 • 13 citations

Gelatinase activity of exoantigens from virulent and non-virulent isolates ofParacoccidioides brasiliensis

1994 • 13 citations

Selective Inactivation of an Extra-cytoplasmic Acid Phosphatase of Yeast-like Cells of Sporothrix schenckii by Sodium Fluoride

1987 • 13 citations

Interaction of Histoplasma capsulatum yeasts and conidia with human and animal macrophages.

1994 • 12 citations

Ultrastructural study of tissue reaction of mice against Sporothrix schenckii infection.

1988 • 12 citations

Mutants ofParacoccidioides brasiliensisstrain IVIC Pb9 affected in dimorphism

1992 • 11 citations

Differential binding of acapsulate and encapsulated strains ofCryptococcus neoformansto human neutrophils

1993 • 8 citations

Binding of Unopsonized Cryptococcus neoformans by Human Bronchoalveolar Macrophages: Inhibition by a Large-Molecular-Size Serum Component

1992 • 6 citations

Fungistatic capacity of sera from guinea pigs injected with various iron solutions: differences between Trichophyton mentagrophytes and Rhizopus oryzae

1982 • 6 citations

Media-induced departures from the usual, temperature-dependent cell shapes of Sporothrix schenckii and concomitant changes in the acid phosphatase isoenzyme patterns.

1987 • 5 citations

Molecular approaches to identify novel targets for future development of antifungal agents

1994 • 5 citations

Ultrastructural study of the interaction of the fungi Sporothrix schenckii and Ceratocystis stenoceras with bone-marrow-derived murine macrophages

1985 • 4 citations

Role of Endotoxin of Aspergillus fumigatus in its Pathogenicity/Die Rolle des Endotoxins von Aspergillus fumigatus in seiner Pathogenität

1983 • 4 citations

Blastomyces dermatitidis and Paracoccidioides brasiliensis

1994 • 2 citations