Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

Infections withCryptococcus neoformansin the Acquired Immunodeficiency Syndrome

1989 • 792 citations

The capsule of Cryptococcus neoformans passively inhibits phagocytosis of the yeast by macrophages

1983 • 245 citations

Immunological Unresponsiveness Induced by Cryptococcal Capsular Polysaccharide Assayed by the Hemolytic Plaque Technique

1972 • 205 citations

Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist.

1994 • 188 citations

Cytokine enhancement of complement‐dependent phagocytosis by macrophages: synergy of tumor necrosis factor‐α and granulocyte‐macrophage colony‐stimulating factor for phagocytosis of Cryptococcus neoformans

1992 • 173 citations

Nonencapsulated Variant of Cryptococcus neoformans I. Virulence Studies and Characterization of Soluble Polysaccharide

1971 • 139 citations

Inhibition of phagocytosis by cryptococcal polysaccharide: dissociation of the attachment and ingestion phases of phagocytosis

1976 • 135 citations

Intrapulmonary growth and dissemination of an avirulent strain of Cryptococcus neoformans in mice depleted of CD4+ or CD8+ T cells.

1991 • 132 citations

Cryptococcus neoformansIII. Inhibition of Phagocytosis

1968 • 131 citations

Killing of Cryptococcus neoformans strains by human neutrophils and monocytes

1991 • 118 citations

CD4+ T cells cause multinucleated giant cells to form around Cryptococcus neoformans and confine the yeast within the primary site of infection in the respiratory tract.

1992 • 116 citations

Non-encapsulated variant of Cryptococcus neoformans. II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide

1977 • 108 citations

Enhancement of HIV-1 infection by the capsular polysaccharide of Cryptococcus neoformans

1992 • 104 citations

Direct interactions of human lymphocytes with the yeast-like organism, Cryptococcus neoformans.

1993 • 104 citations

Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages

1994 • 99 citations

Differential stimulation of murine resident peritoneal cells by selectively opsonized encapsulated and acapsular Cryptococcus neoformans

1988 • 95 citations

Murine natural killer cells are fungicidal to Cryptococcus neoformans

1991 • 95 citations

Encapsulation of Cryptococcus neoformans impairs antigen-specific T-cell responses

1991 • 90 citations

Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans

1994 • 89 citations

Role of human alveolar macrophages as antigen-presenting cells in Cryptococcus neoformans infection.

1994 • 87 citations

Phenotypic and functional characterization of human lymphocytes activated by interleukin-2 to directly inhibit growth of Cryptococcus neoformans in vitro.

1993 • 87 citations

Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans

1991 • 85 citations

Therapy for Cryptococcal Meningitis in Patients with AIDS

1992 • 82 citations

Effects of strain variation, serotype, and structural modification on kinetics for activation and binding of C3 to Cryptococcus neoformans

1993 • 75 citations

Antibody-dependent leukocyte killing of Cryptococcus neoformans.

1983 • 69 citations

Binding of cryptococcal polysaccharide to Cryptococcus neoformans

1984 • 60 citations

Augmentation of GG2EE macrophage cell line-mediated anti-Candida activity by gamma interferon, tumor necrosis factor, and interleukin-1

1990 • 51 citations

Effect of polysaccharide capsule and methods of preparation on human lymphocyte proliferation in response to Cryptococcus neoformans

1993 • 47 citations

Modulation of anti-Candida Activity of Human Alveolar Macrophages by Interferon-gamma or Interleukin-1-alpha

1989 • 44 citations

Responses of murine natural killer cells to binding of the fungal target Cryptococcus neoformans

1991 • 38 citations

Binding of purified and radioiodinated capsular polysaccharides from Cryptococcus neoformans serotype A strains to capsule-free mutants

1986 • 31 citations

POORLY ENCAPSULATEDCRYPTOCOCCUS NEOFORMANSFROM PATIENTS WITH AIDS. I: PRELIMINARY OBSERVATIONS

1986 • 31 citations

Enhancement of HIV-1 replication in peripheral blood mononuclear cells by Cryptococcus neoformans is monocyte-dependent but tumour necrosis factor-independent

1994 • 19 citations

Inhibition of Candidacidal Activity of Polymorphonuclear Cells by Alveolar Macrophage-derived Factor from Lung Cancer Patients

1993 • 18 citations