Damage to Aspergillus fumigatus and Rhizopus oryzae Hyphae by Oxidative and Nonoxidative Microbicidal Products of Human Neutrophils In Vitro

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Oxygen-Dependent Microbial Killing by Phagocytes

1978 • 2,519 citations

Studies on the chlorinating activity of myeloperoxidase.

1976 • 918 citations

Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection

1969 • 697 citations

The neutrophil: Function and clinical disorders

1978 • 670 citations

Quenching of singlet oxygen by tertiary aliphatic amines. Effect of DABCO (1,4-diazabicyclo[2.2.2]octane)

1968 • 453 citations

The Absorption Spectra of I₂, I₃^-, I^-, IO₃^-, S₄O₆⁼ and S₂O₃⁼. Heat of the Reaction I₃^- = I₂ + I^-

1951 • 378 citations

Fungal infection in chronic granulomatous disease

1981 • 361 citations

Myeloperoxidase: Contribution to the Microbicidal Activity of Intact Leukocytes

1970 • 345 citations

Generation of Hydroxyl Radical by Enzymes, Chemicals, and Human Phagocytes In Vitro

1979 • 280 citations

Role of azide in singlet oxygen reactions: Reaction of azide with singlet oxygen.

1972 • 262 citations

Formation of singlet oxygen by the myeloperoxidase-mediated antimicrobial system.

1977 • 262 citations

Evidence for hydroxyl radical production by human neutrophils.

1977 • 257 citations

Bactericidal activity of a superoxide anion-generating system. A model for the polymorphonuclear leukocyte.

1979 • 242 citations

Antifungal Effects of Peroxidase Systems

1969 • 233 citations

Damage to hyphal forms of fungi by human leukocytes in vitro. A possible host defense mechanism in aspergillosis and mucormycosis.

1978 • 209 citations

Human granulocyte generation of hydroxyl radical.

1978 • 191 citations

The fungicidal mechanisms of human monocytes. I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms.

1975 • 191 citations

Damage to Candida albicans Hyphae and Pseudohyphae by the Myeloperoxidase System and Oxidative Products of Neutrophil Metabolism In Vitro

1980 • 162 citations

Hydroxyl radical generation by polymorphonuclear leukocytes measured by electron spin resonance spectroscopy.

1979 • 156 citations

Microbicidal cationic proteins in rabbit alveolar macrophages: a potential host defense mechanism

1980 • 150 citations

Nonoxidative Fungicidal Mechanisms of Mammalian Granulocytes: Demonstration of Components with Candidacidal Activity in Human, Rabbit, and Guinea Pig Leukocytes

1975 • 132 citations

Ethylene formation by polymorphonuclear leukocytes. Role of myeloperoxidase.

1978 • 121 citations

Resistance of Gram-negative Bacteria to Purified Bactericidal Leukocyte Proteins

1980 • 115 citations

Mechanisms for the microbicidal activity of cationic proteins of human granulocytes

1976 • 106 citations

Neutrophil-platelet interaction mediated by myeloperoxidase and hydrogen peroxide.

1980 • 100 citations

SINGLET OXYGEN: A MAJOR REACTIVE SPECIES IN THE FUROCOUMARIN PHOTOSENSITIZED INACTIVATION OF E. COLI RIBOSOMES

1978 • 98 citations

A potential role for hypochlorous acid in granulocyte-mediated tumor cell cytotoxicity

1980 • 95 citations

Microbicidal mechanisms of human granulocytes: synergistic effects of granulocyte elastase and myeloperoxidase or chymotrypsin-like cationic protein

1976 • 91 citations

Extracellular proton release by stimulated neutrophils.

1981 • 86 citations

Hemolysis and iodination of erythrocyte components by a myeloperoxidase- mediated system

1975 • 81 citations

Neutrophil and Eosinophil Granulocytes in Bacterial Infection: Sequential Studies of Cellular and Serum Levels of Granule Proteins

1978 • 80 citations

Myeloperoxidase and singlet oxygen: a reappraisal

1978 • 74 citations

Cytotoxicity for tumor cells of cationic proteins from human neutrophil granules.

1976 • 71 citations

Ambiguity associated with use of singlet oxygen trapping agents in myeloperoxidase-catalyzed oxidations

1978 • 70 citations

Myeloperoxidase--H2O2--halide system: cytotoxic effect on human blood leukocytes

1977 • 69 citations

Localization of Chymotrypsin-Like Cationic Protein, Collagenase and Elastase in Azurophil Granules of Human Neutrophilic Polymorphonuclear Leukocytes

1977 • 69 citations

Production of superoxide radical during the decomposition of potassium peroxochromate(V)

1974 • 58 citations

Lysosomal enzymes in normal and Chediak-Higashi blood leukocytes.

1975 • 49 citations

Natural Host Resistance to Infection with Cryptococcus neoformans: IV. The Effect of Some Cationic Proteins on the Experimental Disease

1966 • 39 citations

Inhibition of specific amino acid uptake in Candida albicans by lysosomal extracts from rabbit alveolar macrophages

1978 • 19 citations