Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism.

1992 • 1,121 citations

Immortalization of murine microglial cells by a v-raf / v-myc carrying retrovirus

1990 • 979 citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

1987 • 958 citations

Infections withCryptococcus neoformansin the Acquired Immunodeficiency Syndrome

1989 • 792 citations

Cryptococcosis in the Acquired Immunodeficiency Syndrome

1985 • 628 citations

Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans

1986 • 347 citations

Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.

1988 • 337 citations

Cryptococcal infections in patients with acquired immune deficiency syndrome

1986 • 318 citations

Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants

1994 • 258 citations

Antioxidant function of fungal melanin

1993 • 214 citations

Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis

1991 • 179 citations

Cytokine enhancement of complement‐dependent phagocytosis by macrophages: synergy of tumor necrosis factor‐α and granulocyte‐macrophage colony‐stimulating factor for phagocytosis of Cryptococcus neoformans

1992 • 173 citations

Tumor necrosis factor-alpha-dependent production of reactive nitrogen intermediates mediates IFN-gamma plus IL-2-induced murine macrophage tumoricidal activity.

1992 • 144 citations

Fungal infections in AIDS patients

1992 • 139 citations

Fungicidal activity of IFN-gamma-activated macrophages. Extracellular killing of Cryptococcus neoformans.

1989 • 131 citations

Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism.

1994 • 120 citations

Melanin as a virulence factor in pathogenic fungi

1990 • 108 citations

Catecholamines and virulence of Cryptococcus neoformans

1990 • 97 citations

Differential stimulation of murine resident peritoneal cells by selectively opsonized encapsulated and acapsular Cryptococcus neoformans

1988 • 95 citations

Localization on encapsulated Cryptococcus neoformans of serum components opsonic for phagocytosis by macrophages and neutrophils

1984 • 93 citations

Catecholamine uptake, melanization, and oxygen toxicity in Cryptococcus neoformans

1991 • 88 citations

Antibody-dependent Killing of Cryptococcus neoformans by Human Peripheral Blood Mononuclear Cells

1974 • 83 citations

Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicity.

1986 • 79 citations

Strain variation in phagocytosis of Cryptococcus neoformans: dissociation of susceptibility to phagocytosis from activation and binding of opsonic fragments of C3

1988 • 76 citations

Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages.

1993 • 70 citations

Experimental model of intracerebral infection with Cryptococcus neoformans: roles of phagocytes and opsonization

1992 • 62 citations

Opsonic Requirements for the Uptake of Cryptococcus neoformans by Human Polymorphonuclear Leukocytes and Monocytes

1982 • 57 citations

Differential host susceptibility to intracerebral infections with Candida albicans and Cryptococcus neoformans

1993 • 33 citations

Activated neutrophils exhibit enhanced phagocytosis of Cryptococcus neoformans opsonized with normal human serum.

1987 • 26 citations