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2002 • 1,583 citations

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

2003 • 1,466 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

Restoration of Viral Immunity in Immunodeficient Humans by the Adoptive Transfer of T Cell Clones

1992 • 1,227 citations

Skewed maturation of memory HIV-specific CD8 T lymphocytes

2001 • 1,025 citations

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

2003 • 999 citations

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL

1996 • 711 citations

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

1998 • 666 citations

Incidence and Natural History of Cytomegalovirus Disease in Patients with Advanced Human Immunodeficiency Virus Disease Treated with Zidovudine

1992 • 526 citations

Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection

2004 • 457 citations

11-color, 13-parameter flow cytometry: Identification of human naive T cells by phenotype, function, and T-cell receptor diversity

2001 • 452 citations

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2003 • 421 citations

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1985 • 417 citations

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1–infected subjects with progressive disease: changes after antiretroviral therapy

2003 • 380 citations

Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts.

1996 • 378 citations

Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8⁺ virus‐specific cytotoxic T lymphocytes

1994 • 359 citations

Protection from cytomegalovirus after transplantation is correlated with immediate early 1–specific CD8 T cells

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Use of overlapping peptide mixtures as antigens for cytokine flow cytometry

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Ex Vivo Profiling of CD8⁺-T-Cell Responses to Human Cytomegalovirus Reveals Broad and Multispecific Reactivities in Healthy Virus Carriers

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T-cell epitope mapping by flow cytometry

1998 • 295 citations

Target Structures of the CD8⁺-T-Cell Response to Human Cytomegalovirus: the 72-Kilodalton Major Immediate-Early Protein Revisited

1999 • 291 citations

Tetramer-based quantification of cytomegalovirus (CMV)–specific CD8+ T lymphocytes in T-cell–depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection

2001 • 290 citations

Cytomegalovirus (CMV) Phosphoprotein 65 Makes a Large Contribution to Shaping the T Cell Repertoire in CMV‐Exposed Individuals

2002 • 285 citations

Analysis of CD8 T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides

2000 • 269 citations

Development of a Candidate HLA A*0201 Restricted Peptide-Based Vaccine Against Human Cytomegalovirus Infection

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1992 • 217 citations

The Memory Cytotoxic T-Lymphocyte (CTL) Response to Human Cytomegalovirus Infection Contains Individual Peptide-Specific CTL Clones That Have Undergone Extensive Expansion In Vivo

1999 • 210 citations

Differential Antigen Presentation Regulates the Changing Patterns of CD8+ T Cell Immunodominance in Primary and Secondary Influenza Virus Infections

2003 • 207 citations

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

2002 • 187 citations

DNA Display I. Sequence-Encoded Routing of DNA Populations

2004 • 163 citations

Identification of Three HLA-A*0201-Restricted Cytotoxic T Cell Epitopes in the Cytomegalovirus Protein pp65 That Are Conserved Between Eight Strains of the Virus

1999 • 141 citations

Large clonal expansions of human virus‐specific memory cytotoxic T lymphocytes within the CD57⁺ CD28^– CD8⁺ T‐cell population

1999 • 127 citations

A systematic comparison of methods to measure HIV-1 specific CD8 T cells

2003 • 127 citations

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Loss of cytomegalovirus (CMV) viraemia following highly active antiretroviral therapy in the absence of specific anti-CMV therapy

1999 • 105 citations

Identification of novel CTL epitopes of CMV-pp65 presented by a variety of HLA alleles

2003 • 100 citations

Discontinuation of maintenance therapy for cytomegalovirus retinitis in HIV-infected patients receiving highly active antiretroviral therapy

2001 • 100 citations

Decrease of Cytomegalovirus Replication in Human Immunodeficiency Virus Infected–Patients after Treatment with Highly Active Antiretroviral Therapy

1999 • 86 citations

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire

1995 • 81 citations

CD8hi+CD57+ T lymphocytes are enriched in antigen-specific T cells capable of down-modulating cytotoxic activity

1998 • 81 citations

Rapid expansion of cytomegalovirus–specific cytotoxic T lymphocytes by artificial antigen-presenting cells expressing a single HLA allele

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Status of long-term asymptomatic HIV-1 infection correlates with viral load but not with virus replication properties and cell tropism

1999 • 63 citations

Cutting Edge: The Related Molecules CD28 and Inducible Costimulator Deliver Both Unique and Complementary Signals Required for Optimal T Cell Activation

2001 • 62 citations

Regulation of CD28 costimulation in human CD8+ T cells.

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Status of Cytomegalovirus Prevention and Treatment in 2000

2000 • 48 citations

Identification of Immune Dominant Cytomegalovirus Epitopes Using Quantitative Real-Time Polymerase Chain Reactions to Measure Interferon-γ Production by Peptide-Stimulated Peripheral Blood Mononuclear Cells

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CD4 T cells guarantee optimal competitive fitness of CD8 memory T cells

2003 • 33 citations

Identification of the HLA-A24 Peptide Epitope within Cytomegalovirus Protein pp65 Recognized by CMV-Specific Cytotoxic T Lymphocytes

2001 • 31 citations

Status of long‐term asymptomatic HIV‐1 infection correlates with viral load but not with virus replication properties and cell tropism

1999 • 27 citations

Results of a Cytomegalovirus (CMV)–Specific CD8⁺/Interferon‐γ⁺Cytokine Flow Cytometry Assay Correlate with Clinical Evidence of Protective Immunity in Patients with AIDS with CMV Retinitis

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Modulation of HLA-A*0201-Restricted T Cell Responses by Natural Polymorphism in the IE1315–324 Epitope of Human Cytomegalovirus

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