The Memory Cytotoxic T-Lymphocyte (CTL) Response to Human Cytomegalovirus Infection Contains Individual Peptide-Specific CTL Clones That Have Undergone Extensive Expansion In Vivo

Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

1995 • 1,828 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Restoration of Viral Immunity in Immunodeficient Humans by the Adoptive Transfer of T Cell Clones

1992 • 1,227 citations

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

1994 • 788 citations

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL

1996 • 711 citations

Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease

1991 • 686 citations

Human T-cell receptor variable gene segment families

1995 • 663 citations

The T Cell Receptor

1987 • 554 citations

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

1992 • 531 citations

Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.

1993 • 427 citations

Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites.

1991 • 332 citations

Expanded CD4+ and CD8+ T cell clones in elderly humans.

1997 • 307 citations

Clonal predominance of T cell receptors within the CD8+ CD45RO+ subset in normal human subjects.

1993 • 298 citations

Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.

1994 • 289 citations

An alloresponse in humans is dominated by cytotoxic T lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: implications for graft-versus-host disease.

1994 • 275 citations

Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.

1995 • 268 citations

Benign Monoclonal Gammapathy

1984 • 249 citations

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

1994 • 232 citations

Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis.

1995 • 213 citations

Single-Cell PCR Analysis of TCR Repertoires Selected by Antigen In Vivo: A High Magnitude CD8 Response Is Comprised of Very Few Clones

1996 • 174 citations

Variation in human T cell receptor V_β and J_β repertoire: analysis using anchor polymerase chain reaction

1992 • 164 citations

Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset.

1995 • 162 citations

CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus.

1995 • 160 citations

Limited CD4+ T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy

1998 • 153 citations

Oligoclonal Expansions of CD8+ T Cells in Chronic HIV Infection Are Antigen Specific

1998 • 150 citations

Human cytomegalovirus-specific cytotoxic T cells: their precursor frequency and stage specificity

1988 • 125 citations

How αβ T-cell receptors ‘see’ peptide/MHC complexes

1993 • 124 citations

HLA-Restricted Cytotoxic T Lymphocytes Are an Early Immune Response and Important Defense Mechanism in Cytomegalovirus Infections

1984 • 110 citations

DECLINING T-CELL IMMUNITY TO INFLUENZA, 1977-82

1983 • 109 citations

Oligoclonality of CD8 + T cells in health and disease: Aging, infection, or immune regulation?

1996 • 107 citations

Epitope-dependent Selection of Highly Restricted or Diverse T Cell Receptor Repertoires in Response to Persistent Infection by Epstein-Barr Virus

1997 • 106 citations

Analysis of the T-cell receptor repertoire of human T-cell leukemia virus type 1 (HTLV-1) Tax-specific CD8+ cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion

1996 • 106 citations

Conservation of T cell receptor usage by HLA B27‐restricted influenza‐specific cytotoxic T lymphocytes suggests a general pattern for antigen‐specific major histocompatibility complex class I‐restricted responses

1993 • 104 citations

The MHC class l-restricted T cell response to Sendai virus infection in C57BL/6 mice: a single immunodominant epitope elicits an extremely diverse repertoire of T cells

1994 • 95 citations

Development of Epstein-Barr virus-specific memory T cell receptor clonotypes in acute infectious mononucleosis.

1996 • 87 citations

Oligoclonality in the Human CD8+ T Cell Repertoire in Normal Subjects and Monozygotic Twins: Implications for Studies of Infectious and Autoimmune Diseases

1995 • 82 citations

The genetic contribution to human T-cell receptor repertoire.

1991 • 76 citations

Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival

1991 • 65 citations

A persistent T cell expansion in the peripheral blood of a normal adult male: a new clinical entity?

1992 • 57 citations

T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity

1994 • 43 citations

Diversity of T cell receptors specific for the VSV antigenic peptide (N52-59) Bound by the H-2Kb class I molecule

1995 • 41 citations

Organization of the T-cell receptor alpha-chain gene and rearrangement in human T-cell leukaemias.

1986 • 16 citations

[Cytomegalovirus infection in AIDS].

1994 • 13 citations