Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Dominance and Crypticity of T Cell Antigenic Determinants

1993 • 838 citations

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

Future influenza vaccines and the use of genetic recombinants.

1969 • 386 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

1986 • 304 citations

Two better cell lines for making hybridomas expressing specific T cell receptors.

1989 • 300 citations

Regulation of TCR α and β gene allelic exclusion during T-cell development

1992 • 284 citations

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes.

1993 • 247 citations

The binary logic of antigen processing and presentation to T cells

1990 • 235 citations

Mechanisms influencing the immunodominance of T cell determinants.

1988 • 227 citations

Requirement for Cotolerogenic Gene Products in the Clonal Deletion of I-E Reactive T Cells

1990 • 193 citations

Antigen presentation: structural themes and functional variations

1991 • 171 citations

The Human T-Cell Receptor TCRAC/TCRDC (Cα/Cdelta;) Region: Organization, Sequence, and Evolution of 97.6 kb of DNA

1994 • 169 citations

Synthesis and cellular location of the ten influenza polypeptides individually expressed by recombinant vaccinia viruses

1987 • 166 citations

A role for clonal inactivation in T cell tolerance to Mis-1a

1990 • 166 citations

Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope.

1993 • 150 citations

Antigen processing at the molecular level

1987 • 137 citations

Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice.

1993 • 136 citations

Anti-influenza virus cytotoxic T lymphocytes recognize the three viral polymerases and a nonstructural protein: responsiveness to individual viral antigens is major histocompatibility complex controlled

1987 • 121 citations

Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.

1989 • 115 citations

A Large Deletion Within the T-Cell Receptor Beta-Chain Gene Complex in New Zealand White Mice

1985 • 105 citations

Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells

1987 • 99 citations

The MHC class l-restricted T cell response to Sendai virus infection in C57BL/6 mice: a single immunodominant epitope elicits an extremely diverse repertoire of T cells

1994 • 95 citations

Antigen-induced lymphomagenesis: identification of a murine B cell lymphoma with known antigen specificity.

1983 • 89 citations

Selective Elements for the Vß Region of the T Cell Receptor: MIs and the Bacterial Toxic Mitogens

1991 • 82 citations

Murine cytotoxic T lymphocyte recognition of individual influenza virus proteins. High frequency of nonresponder MHC class I alleles.

1988 • 79 citations

Specificities of Killing by T Lymphocytes Generated against Syngeneic SV40 Transformants: Studies Employing Recombinants within the H-2 Complex

1979 • 74 citations

Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice.

1990 • 69 citations

T cell receptor alpha-chain influences reactivity to Mls-1 in V beta 8.1 transgenic mice.

1992 • 69 citations

Involvement of both T cell receptor V_α and V_β variable region domains and α chain junctional region in viral antigen recognition

1991 • 68 citations

Tolerance to Self Antigens Shapes the T‐Cell Repertoire

1989 • 62 citations

Limitations in plasticity of the T-cell receptor repertoire.

1991 • 62 citations

Characterization of two distinct major histocompatibility complex class I Kk-restricted T-cell epitopes within the influenza A/PR/8/34 virus hemagglutinin

1991 • 58 citations

T-cell receptor alpha-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains.

1988 • 50 citations

Low responder MHC alleles for Tc recognition of influenza nucleoprotein

1986 • 37 citations

Analysis of the primary T-cell response to Sendai virus infection in C57BL/6 mice: CD4+ T-cell recognition is directed predominantly to the hemagglutinin-neuraminidase glycoprotein

1994 • 36 citations

A nonimmunodominant nucleoprotein-derived peptide is presented by influenza A virus-infected H-2b cells.

1994 • 30 citations

Functional consequences of a T cell receptor D beta 2 and J beta 2 gene segment deletion.

1990 • 28 citations

Immunodominance is altered in T cell receptor (beta-chain) transgenic mice without the generation of a hole in the repertoire.

1991 • 26 citations

MHC-specific recognition of a bacterial superantigen by weakly reactive T cells.

1994 • 22 citations

Virus-specific CD8+ T-cell responses in mice transgenic for a T-cell receptor beta chain selected at random

1994 • 17 citations

Holes in the T cell repertoire to myelin basic protein owing to the absence of the D beta 2-J beta 2 gene cluster: implications for T cell receptor recognition and autoimmunity.

1994 • 12 citations

Deleted Work

1955 • 0 citations

Cited By (0)

No citing papers found in database