The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

Evidence for a Novel Gene Associated With Low Tumor Metastatic Potential

1988 • 1,304 citations

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

1995 • 822 citations

Abnormal Centrosome Amplification in the Absence of p53

1996 • 802 citations

Myc activates telomerase

1998 • 650 citations

Centrosome defects and genetic instability in malignant tumors.

1998 • 583 citations

Centrosome composition and microtubule anchoring mechanisms

2002 • 557 citations

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation.

1993 • 514 citations

Genomic instability in Gadd45a-deficient mice

1999 • 499 citations

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

1997 • 483 citations

Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins.

1993 • 476 citations

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2–Cyclin A

1999 • 476 citations

Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

2001 • 417 citations

γ-Tubulin is present in Drosophila melanogaster and homo sapiens and is associated with the centrosome

1991 • 405 citations

Centrosome-Dependent Exit of Cytokinesis in Animal Cells

2001 • 396 citations

Re-evaluating centrosome function

2001 • 392 citations

A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase

1990 • 353 citations

Centrosomes Enhance the Fidelity of Cytokinesis in Vertebrates and Are Required for Cell Cycle Progression

2001 • 340 citations

Requirement of a Centrosomal Activity for Cell Cycle Progression Through G ₁ into S Phase

2001 • 336 citations

The human Nm23/nucleoside diphosphate kinases.

2000 • 334 citations

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

1999 • 329 citations

Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification

1999 • 315 citations

BRCA1 is associated with the centrosome during mitosis

1998 • 311 citations

Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast.

1999 • 306 citations

Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.

1993 • 298 citations

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression

1999 • 284 citations

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

2000 • 281 citations

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

2000 • 274 citations

9 Nucleoside Diphosphokinases

1973 • 274 citations

The centrosome in vertebrates: more than a microtubule-organizing center

2001 • 232 citations

Association of centrosomal kinaseSTK15/BTAK mRNA expression with chromosomal instability in human breast cancers

2001 • 231 citations

A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential.

1993 • 214 citations

Phosphorylation of ATP-Citrate Lyase by Nucleoside Diphosphate Kinase

1995 • 192 citations

Interaction and Feedback Regulation between STK15/BTAK/Aurora-A Kinase and Protein Phosphatase 1 through Mitotic Cell Division Cycle

2001 • 189 citations

Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway

2000 • 146 citations

Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity

1997 • 141 citations

Sth1p, a Saccharomyces cerevisiae Snf2p/Swi2p Homolog, Is an Essential ATPase in RSC and Differs From Snf/Swi in Its Interactions With Histones and Chromatin-Associated Proteins

1998 • 119 citations

A Novel Serine/Threonine‐Specific Protein Phosphotransferase Activity of Nm23/Nucleoside‐Diphosphate Kinase

1995 • 101 citations

Effects of cytokine‐mediated modulation of nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells

1995 • 99 citations

Integration of the centrosome in cell cycle control, stress response and signal transduction pathways

2002 • 99 citations

MAPK Mediates RAS-induced Chromosome Instability

1999 • 95 citations

Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line.

1995 • 93 citations

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

1998 • 91 citations

Centrosome Duplication

2001 • 85 citations

Do Centrosome Abnormalities Lead to Cancer?

2001 • 70 citations

Cdc20 associates with the kinase aurora2/Aik

1999 • 68 citations

The Association of the Nm23-M1 Protein and β-Tubulin Correlates with Cell Differentiation

1995 • 67 citations

The non-catalytic domain of the Xenopus laevis auroraA kinase localises the protein to the centrosome

2001 • 51 citations

Nm23 and tumour metastasis: basic and translational advances.

1998 • 51 citations

Identification of the Tumor Metastasis Suppressor Nm23-H1/Nm23-R1 as a Constituent of the Centrosome

2001 • 42 citations

Centrosome duplication: Three kinases come up a winner!

2001 • 35 citations

The contribution of epigenetic changes to abnormal centrosomes and genomic instability in breast cancer.

2001 • 27 citations

A cromoglycate binding protein from rat mast cells of a leukemia line is a nucleoside diphosphate kinase

1992 • 24 citations

Gamma-tubulin distribution in interphase and mitotic cells upon stabilization and depolymerization of microtubules.

2000 • 11 citations

Alternative splicing in 5'-untranslational region of STK-15 gene, encoding centrosome associated kinase, in breast cancer cell lines

2000 • 8 citations