The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1995 • 1,407 citations

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

1995 • 822 citations

The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

2000 • 713 citations

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

1997 • 483 citations

Polo-like kinases: a team that plays throughout mitosis

1998 • 424 citations

The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast

1999 • 404 citations

Regulation of the APC and the exit from mitosis

1999 • 375 citations

Polo-like kinases: positive regulators of cell division from start to finish

1998 • 346 citations

The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis

1999 • 333 citations

Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases

1999 • 318 citations

AIR-2: An Aurora/Ipl1-related Protein Kinase Associated with Chromosomes and Midbody Microtubules Is Required for Polar Body Extrusion and Cytokinesis in Caenorhabditis elegans Embryos

1998 • 303 citations

Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.

1993 • 301 citations

Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation.

1994 • 271 citations

Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1

1997 • 265 citations

The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

1998 • 240 citations

Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship

1992 • 199 citations

Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit.

1992 • 198 citations

A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos

1998 • 184 citations

Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p

1999 • 149 citations

The kinase Eg2 is a component of the Xenopus oocyte progesterone-activated signaling pathway

1998 • 147 citations

A Novel Mammalian, Mitotic Spindle–associated Kinase Is Related to Yeast and Fly Chromosome Segregation Regulators

1997 • 138 citations

Requirement for cAMP-PKA Pathway Activation by M Phase-Promoting Factor in the Transition from Mitosis to Interphase

1996 • 137 citations

Protein Kinase Profile of Sperm and Eggs: Cloning and Characterization of Two Novel Testis-Specific Protein Kinases (AIE1, AIE2) Related to Yeast and Fly Chromosome Segregation Regulators

1998 • 135 citations

The spindle checkpoint

1998 • 113 citations

Cloning of STK13, a Third Human Protein Kinase Related toDrosophilaAurora and Budding Yeast Ipl1 That Maps on Chromosome 19q13.3–ter

1998 • 89 citations

cDNA Cloning, Expression, Subcellular Localization, and Chromosomal Assignment of Mammalian Aurora Homologues, Aurora-Related Kinase (ARK) 1 and 2

1998 • 81 citations

Protein kinases in control of the centrosome cycle

1999 • 77 citations

The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism

1999 • 77 citations

Type 1 Protein Phosphatase Acts in Opposition to Ipll Protein Kinase in Regulating Yeast Chromosome Segregation

1994 • 73 citations

Cdc20 associates with the kinase aurora2/Aik

1999 • 68 citations

ayk1, a novel mammalian gene related to Drosophila aurora centrosome separation kinase, is specifically expressed during meiosis

1997 • 66 citations

Regulation of the Cyclin B Degradation System by an Inhibitor of Mitotic Proteolysis

1998 • 63 citations

Defects in Saccharomyces cerevisiae protein phosphatase type I activate the spindle/kinetochore checkpoint

1999 • 60 citations

Cell cycle: Checkpoint proteins and kinetochores

1997 • 44 citations