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Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

Data up to Jan 2025

Published1999
Citations329
References18

Total Citations Per Year

Abstract

References (18)

Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycle

1995 • 918 citations

Abnormal Centrosome Amplification in the Absence of p53

1996 • 802 citations

Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15.

1992 • 638 citations

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

1994 • 543 citations

Requirement of Cdk2-Cyclin E Activity for Repeated Centrosome Reproduction in Xenopus Egg Extracts

1999 • 505 citations

Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells

1995 • 393 citations

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells.

1995 • 301 citations

Chemical inhibitors of cyclin-dependent kinases

1996 • 251 citations

Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin.

1988 • 222 citations

A reversible arrest point in the late G1 phase of the mammalian cell cycle

1990 • 203 citations

Centrosome duplication continues in cycloheximide-treated Xenopus blastulae in the absence of a detectable cell cycle.

1990 • 176 citations

Chemical inhibitors of cyclin-dependent kinases

1997 • 138 citations

Protein synthesis and the cell cycle: centrosome reproduction in sea urchin eggs is not under translational control.

1990 • 108 citations

The Coordination of Centrosome Reproduction with Nuclear Events of the Cell Cycle in the Sea Urchin Zygote

1998 • 90 citations

A Role for Cyclin E/Cdk2 in the Timing of the Midblastula Transition inXenopusEmbryos

1997 • 65 citations

p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine.

1996 • 60 citations

Dependence of centriole formation on protein synthesis.

1976 • 46 citations

Entry into mitosis without Cdc2 kinase activation

1998 • 25 citations

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Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells (1999) – Current Biology | Metascience Observatory Explorer