Inhibition of Brain G _z GAP and Other RGS Proteins by Palmitoylation of G Protein α Subunits

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins

1996 • 573 citations

RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

1996 • 547 citations

RGS Proteins and Signaling by Heterotrimeric G Proteins

1997 • 522 citations

Lipid Modifications of Trimeric G Proteins

1995 • 468 citations

RGS4 and GAIP are GTPase-activating proteins for G _qα and block activation of phospholipase Cβ by γ-thio-GTP-G _qα

1997 • 355 citations

RGS10 is a selective activator of Gαi GTPase activity

1996 • 354 citations

Lipid modifications of G proteins: alpha subunits are palmitoylated.

1993 • 336 citations

Activation and depalmitoylation of Gsα

1994 • 336 citations

Purification of Recombinant G Proteins from Sf9 Cells by Hexahistidine Tagging of Associated Subunits

1995 • 332 citations

Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha.

1993 • 293 citations

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

1995 • 291 citations

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

1990 • 282 citations

Lipid modifications of G protein subunits.

1991 • 274 citations

Reversible palmitoylation of signaling proteins

1997 • 256 citations

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

1988 • 251 citations

Receptor regulation of G-protein palmitoylation.

1994 • 229 citations

A new family of G-protein regulators — the RGS proteins

1997 • 201 citations

Autoacylation of G Protein α Subunits

1996 • 197 citations

Increased palmitoylation of the Gs protein alpha subunit after activation by the beta-adrenergic receptor or cholera toxin.

1993 • 180 citations

Palmitoylation of a G protein alpha i subunit requires membrane localization not myristoylation.

1994 • 111 citations

Reciprocal regulation of G _sα by palmitate and the βγ subunit

1996 • 99 citations

The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro

1997 • 90 citations

Fatty Acylation of α2

1995 • 90 citations

Regulation of Gq/11α by the Gonadotropin-Releasing Hormone Receptor

1997 • 88 citations

Protein Modification: Palmitoylation in G-protein signaling pathways

1995 • 78 citations

Partial Constitutive Activation of Pheromone Responses by a Palmitoylation-Site Mutant of a G Protein α Subunit in Yeast

1996 • 60 citations

Regulation of Gq/11 by the Gonadotropin-Releasing Hormone Receptor

1997 • 44 citations

Palmitoylation but not the extreme amino‐terminus of G_qα is required for coupling to the NK2 receptor

1994 • 43 citations

G _sα contains an unidentified covalent modification that increases its affinity for adenylyl cyclase

1997 • 38 citations

The palmitoylation status of the G-protein Go1 α regulates its activity of interaction with the plasma membrane

1994 • 38 citations

[16] Preparation of guanine nucleotide-free G proteins

1991 • 11 citations