Partial Constitutive Activation of Pheromone Responses by a Palmitoylation-Site Mutant of a G Protein α Subunit in Yeast

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

THE BIOLOGY AND ENZYMOLOGY OF EUKARYOTIC PROTEIN ACYLATION

1988 • 787 citations

Lipid Modifications of Trimeric G Proteins

1995 • 468 citations

Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha.

1993 • 293 citations

Lipid modifications of G protein subunits.

1991 • 274 citations

Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain.

1992 • 182 citations

Increased palmitoylation of the Gs protein alpha subunit after activation by the beta-adrenergic receptor or cholera toxin.

1993 • 180 citations

G-protein Palmitoyltransferase Activity Is Enriched in Plasma Membranes

1996 • 170 citations

Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341.

1993 • 158 citations

A novel N-terminal motif for palmitoylation of G-protein α subunits

1993 • 156 citations

Functional Importance of the Amino Terminus of Gqα

1996 • 143 citations

Palmitoylation of a G protein alpha i subunit requires membrane localization not myristoylation.

1994 • 111 citations

Sec15 protein, an essential component of the exocytotic apparatus, is associated with the plasma membrane and with a soluble 19.5S particle.

1991 • 91 citations

The α‐subunits of G‐proteins G₁₂ and G₁₃ are palmitoylated, but not amidically myristoylated

1994 • 63 citations

Demyristoylation of the major substrate of protein kinase C (MARCKS) by the cytoplasmic fraction of brain synaptosomes.

1994 • 57 citations

Signal transduction and growth control in yeast

1995 • 55 citations

N-terminal fatty acylation of the α-subunit of the G-protein Gi1: only the myristoylated protein is a substrate for palmitoylation

1994 • 49 citations

Translocation of alpha subunits of stimulatory guanine nucleotide-binding proteins through stimulation of the prostacyclin receptor in mouse mastocytoma cells.

1992 • 44 citations

The palmitoylation status of the G-protein Go1 α regulates its activity of interaction with the plasma membrane

1994 • 38 citations

Palmitoylation negative mutants of murine G11α have decreased ability to interact with the plasma membrane when expressed in COS-1 cells

1995 • 4 citations