Lipid modifications of G protein subunits.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

THE BIOLOGY AND ENZYMOLOGY OF EUKARYOTIC PROTEIN ACYLATION

1988 • 787 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.

1984 • 498 citations

Myristylation of picornavirus capsid protein VP4 and its structural significance

1987 • 475 citations

G proteins control diverse pathways of transmembrane signaling ¹

1989 • 399 citations

Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding

1990 • 389 citations

Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins.

1987 • 359 citations

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

1990 • 282 citations

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.

1990 • 277 citations

Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.

1987 • 276 citations

Expression of Gsα in Escherichia coli

1989 • 262 citations

The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.

1986 • 261 citations

The purified alpha subunits of Go and Gi from bovine brain require beta gamma for association with phospholipid vesicles.

1986 • 253 citations

Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.

1990 • 245 citations

Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini.

1990 • 230 citations

G protein gamma subunits contain a 20-carbon isoprenoid.

1990 • 229 citations

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

1990 • 225 citations

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

1990 • 208 citations

Fatty acylated proteins as components of intracellular signaling pathways

1990 • 202 citations

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

1990 • 162 citations

Chromatographic resolution and immunologic identification of the alpha 40 and alpha 41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain.

1988 • 144 citations

G protein .beta..gamma. subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of .alpha. subunits by pertussis toxin but differential interactions with Gs.alpha.

1989 • 139 citations

Specific and saturable binding of pp60v-src to plasma membranes: Evidence for a myristyl-src receptor

1989 • 137 citations

Characterization of transducin from bovine retinal rod outer segments. Participation of the amino-terminal region of T alpha in subunit interaction.

1987 • 131 citations

Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling.

1990 • 118 citations

Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.

1987 • 111 citations

The amino terminus of G protein alpha subunits is required for interaction with beta gamma.

1988 • 104 citations

Hydroxylamine-stable covalent linkage of myristic acid in Goα, a guanine nucleotide-binding protein of bovine brain

1987 • 91 citations

Heteroatom-substituted fatty acid analogs as substrates for N-myristoyltransferase: an approach for studying both the enzymology and function of protein acylation.

1988 • 80 citations

Isolation of the alpha subunits of GTP-binding regulatory proteins by affinity chromatography with immobilized beta gamma subunits.

1989 • 65 citations

High affinity binding of an N-terminal myristoylated p60 peptide

1989 • 34 citations

Post-translational modification of proteins by lipids

1989 • 12 citations