Expression of Three Membrane-type Matrix Metalloproteinases (MT-MMPs) in Rat Vascular Smooth Muscle Cells and Characterization of MT3-MMPs with and without Transmembrane Domain

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

The smooth muscle cell in culture

1979 • 1,546 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

Chapter 1: Interferons (IFNs)

1986 • 793 citations

Synthetic oligonucleotide probes deduced from amino acid sequence data

1985 • 759 citations

Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat.

1994 • 599 citations

The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation

1996 • 564 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Identification of the Second Membrane-type Matrix Metalloproteinase (MT-MMP-2) Gene from a Human Placenta cDNA Library

1995 • 474 citations

Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

1996 • 392 citations

The collagenase gene family in humans consists of at least four members

1988 • 364 citations

Activation of a recombinant membrane type 1‐matrix metalloproteinase (MT1‐MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)‐2

1996 • 358 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2

1993 • 338 citations

Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.

1996 • 330 citations

Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.

1987 • 323 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 319 citations

Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

1993 • 283 citations

Kinetics of cellular proliferation after arterial injury. III. Endothelial and smooth muscle growth in chronically denuded vessels.

1986 • 281 citations

Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery

1994 • 270 citations

The C-terminal Region of Membrane Type Matrix Metalloproteinase Is a Functional Transmembrane Domain Required for Pro-gelatinase A Activation

1995 • 269 citations

Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells.

1990 • 249 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 244 citations

Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes

1995 • 242 citations

Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.

1993 • 209 citations

Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes

1991 • 201 citations

Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line.

1990 • 194 citations

Involvement of extracellular-matrix-degrading metalloproteinases in rabbit aortic smooth-muscle cell proliferation

1992 • 190 citations

The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases

1992 • 190 citations

Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia.

1993 • 182 citations

Collagen-induced activation of the M(r) 72,000 type IV collagenase in normal and malignant human fibroblastoid cells.

1992 • 154 citations

Mechanisms of arterial graft failure. II. Chronic endothelial and smooth muscle cell proliferation in healing polytetrafluoroethylene prostheses

1986 • 138 citations

Cellular activation of the 72 kDa type IV procollagenase/TIMP-2 complex

1993 • 138 citations

Immunohistochemical localization of matrix metallloproteinase 2 and its specific inhibitor timp‐2 in neoplastic tissues with monclonal antibodies

1994 • 137 citations

Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.

1993 • 136 citations

Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells.

1994 • 124 citations

Processing of a precursor of 72-kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase.

1996 • 110 citations

Production of tissue collagenase (matrix metalloproteinase 1) by human aortic smooth muscle cells in response to platelet-derived growth factor

1991 • 91 citations

Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain

1995 • 90 citations

Comparison of Extracellular Matrix-Degrading Activities between 64-kDa and 90-kDa Gelatinases Purified in Inhibitor-Free Forms from Human Schwannoma Cells1

1992 • 84 citations

Synthesis of Latent Collagenase and Collagenase Inhibitor by Bovine Aortic Medial Explants and Cultured Medial Smooth Muscle Cells

1989 • 25 citations