Cellular activation of the 72 kDa type IV procollagenase/TIMP-2 complex

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Tumor invasion and metastasis: an imbalance of positive and negative regulation.

1991 • 711 citations

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 • 699 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

1989 • 579 citations

Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin)

1990 • 431 citations

Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.

1990 • 379 citations

The Activation of Human Type IV Collagenase Proenzyme

1989 • 347 citations

Human skin fibroblast collagenase inhibitor. Purification and biochemical characterization.

1983 • 259 citations

Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. Induction and endogenous activation of collagenase, 72-kDa gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinases.

1990 • 235 citations

The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins.

1990 • 202 citations

Detergent-activation of latent collagenase and resolution of its component molecules

1982 • 202 citations

Solubilization of active opiate receptors.

1980 • 199 citations

Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2

1991 • 198 citations

Purification and Characterization of Two Related but Distinct Metalloproteinase Inhibitors Secreted by Bovine Aortic Endothelial Cells

1989 • 193 citations

Binding of tissue inhibitor of metalloproteinases 2 to two distinct sites on human 72-kDa gelatinase. Identification of a stabilization site.

1991 • 138 citations

Inhibition of Human Type IV Collagenase by a Highly Conserved Peptide Sequence Derived from Its Prosegment

1991 • 39 citations

Structured approach to the investigation of anaemia in patients with rheumatoid arthritis.

1992 • 23 citations