PCAF Interacts with Tax and Stimulates Tax Transactivation in a Histone Acetyltransferase-Independent Manner

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1995 • 1,197 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

1998 • 984 citations

Role of CBP/P300 in nuclear receptor signalling

1996 • 935 citations

Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.

1984 • 886 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

1999 • 764 citations

Binding and modulation of p53 by p300/CBP coactivators

1997 • 698 citations

Regulation of activity of the transcription factor GATA-1 by acetylation

1998 • 686 citations

Recruitment of p300/CBP in p53-Dependent Signal Pathways

1997 • 671 citations

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

1998 • 639 citations

Synergistic activation of transcription by CBP and p53

1997 • 599 citations

Acetylation of general transcription factors by histone acetyltransferases

1997 • 588 citations

Histone-like TAFs within the PCAF Histone Acetylase Complex

1998 • 534 citations

The p300/CBP family: integrating signals with transcription factors and chromatin

1997 • 482 citations

GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein

1997 • 437 citations

A Subset of TAFIIs Are Integral Components of the SAGA Complex Required for Nucleosome Acetylation and Transcriptional Stimulation

1998 • 419 citations

Differential Roles of p300 and PCAF Acetyltransferases in Muscle Differentiation

1997 • 419 citations

Commentary on and reprint of Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC, Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T cell lymphoma, in Proceedings of the National Academy of Sciences (1980) 77:7415–7419

2000 • 418 citations

Overlapping but Distinct Patterns of Histone Acetylation by the Human Coactivators p300 and PCAF within Nucleosomal Substrates

1999 • 411 citations

Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.

1990 • 401 citations

The histone acetylase PCAF is a nuclear receptor coactivator

1998 • 389 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector.

1989 • 359 citations

CBP as a transcriptional coactivator of c-Myb.

1996 • 347 citations

Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP

1996 • 344 citations

Decoding the nucleosome

1993 • 342 citations

Acetylation of HMG I(Y) by CBP Turns off IFNβ Expression by Disrupting the Enhanceosome

1998 • 321 citations

Human p300 Protein Is a Coactivator for the Transcription Factor MyoD

1996 • 319 citations

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.

1995 • 318 citations

Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction.

1992 • 318 citations

Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture

1992 • 311 citations

HIV-1 Tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

1998 • 291 citations

Transcriptional Regulation of the MDR1 Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y

1998 • 289 citations

Activation of Integrated Provirus Requires Histone Acetyltransferase

1998 • 284 citations

A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure

1998 • 277 citations

The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

1993 • 258 citations

Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat

1987 • 251 citations

Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer.

1991 • 188 citations

CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein.

1997 • 183 citations

Anchoring of CREB Binding Protein to the Human T-Cell Leukemia Virus Type 1 Promoter: a Molecular Mechanism of Tax Transactivation

1997 • 179 citations

P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor

1999 • 177 citations

Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer.

1986 • 175 citations

An Exposed KID-Like Domain in Human T-Cell Lymphotropic Virus Type 1 Tax Is Responsible for the Recruitment of Coactivators CBP/p300

1998 • 174 citations

CREB-binding Protein Activates Transcription through Multiple Domains

1996 • 170 citations

Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB).

1993 • 161 citations

NF-Y Is Associated with the Histone Acetyltransferases GCN5 and P/CAF

1998 • 145 citations

Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins

1992 • 135 citations

E1A directly binds and regulates the P/CAF acetyltransferase

1998 • 124 citations

Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway.

1991 • 124 citations

A unique enhancer element for the trans activator (p40tax) of human T-cell leukemia virus type I that is distinct from cyclic AMP- and 12-O-tetradecanoylphorbol-13-acetate-responsive elements

1989 • 122 citations

Human T-Cell Leukemia Virus Type 1 Tax Requires Direct Access to DNA for Recruitment of CREB Binding Protein to the Viral Promoter

1998 • 120 citations

Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors

1995 • 119 citations

Differential Transcriptional Activation by Human T-Cell Leukemia Virus Type 1 Tax Mutants Is Mediated by Distinct Interactions with CREB Binding Protein and p300

1998 • 119 citations

Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes

1997 • 104 citations

Recent Advances in the Molecular Biology of HTLV-1: Trans-Activation of Viral and Cellular Genes

1987 • 104 citations

Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.

1994 • 97 citations

Specific Acetylation of Chromosomal Protein HMG-17 by PCAF Alters Its Interaction with Nucleosomes

1999 • 89 citations

Indirect binding of human T-cell leukemia virus type I tax1 to a responsive element in the viral long terminal repeat.

1989 • 85 citations

Complex Formation between CREB and Tax Enhances the Binding Affinity of CREB for the Human T-Cell Leukemia Virus Type 1 21-Base-Pair Repeats

1996 • 83 citations

Human T-cell lymphotropic virus type I

1996 • 74 citations

Direct interaction of CREB protein with 21 bp Tax-response elements of HTLV-ILTR.

1992 • 69 citations

The Coactivator CBP Stimulates Human T-cell Lymphotrophic Virus Type I Tax Transactivation in Vitro

1998 • 67 citations

Long-distance transcriptional enhancement by the histone acetyltransferase PCAF

1998 • 64 citations

Definition of a minimal activation domain in human T-cell leukemia virus type I Tax

1995 • 58 citations

Interaction of the Human T-Cell Lymphotropic Virus Type 1 Tax Transactivator with Transcription Factor IIA

1996 • 55 citations

HTLV-1 21 bp Repeat Sequences Facilitate Stable Association Between Tax and CREB to Increase CREB Binding Affinity

1996 • 51 citations

HTLV-1 oncoprotein Tax deregulates transcription of cellular genes through multiple mechanisms

1995 • 48 citations

Electroporation of viral transactivator proteins into lymphocyte suspension cells

1992 • 45 citations

Physical and Functional Interaction between the Human T-Cell Lymphotropic Virus Type 1 Tax₁ Protein and the CCAAT Binding Protein NF-Y

1997 • 34 citations

Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA

1995 • 29 citations

Mechanisms of control of gene expression

1987 • 6 citations