Activation of Integrated Provirus Requires Histone Acetyltransferase

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Current protocols in molecular biology

1988 • 4,543 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Histone acetylation in chromatin structure and transcription

1997 • 2,834 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

Role of CBP/P300 in nuclear receptor signalling

1996 • 935 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

Arginine-Mediated RNA Recognition: the Arginine Fork

1991 • 757 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

Recruitment of p300/CBP in p53-Dependent Signal Pathways

1997 • 671 citations

The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.

1996 • 662 citations

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

1989 • 644 citations

CONTROL OF RNA INITIATION AND ELONGATION AT THE HIV-1 PROMOTER

1994 • 613 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

1995 • 578 citations

Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

1996 • 571 citations

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

1995 • 534 citations

RNA Helicase A Mediates Association of CBP with RNA Polymerase II

1997 • 532 citations

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

1996 • 525 citations

Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.

1993 • 490 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

Transcription Factor Loading on the MMTV Promoter: A Bimodal Mechanism for Promoter Activation

1992 • 411 citations

HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure.

1990 • 400 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

1991 • 372 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.

1991 • 360 citations

CBP as a transcriptional coactivator of c-Myb.

1996 • 347 citations

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

1995 • 338 citations

Human p300 Protein Is a Coactivator for the Transcription Factor MyoD

1996 • 319 citations

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro.

1995 • 318 citations

Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300.

1995 • 305 citations

Identification of a Cellular Protein That Specifically Interacts with the Essential Cysteine Region of the HIV-1 Tat Transactivator

1996 • 284 citations

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

1992 • 276 citations

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

1996 • 255 citations

TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter

1990 • 253 citations

Direct interaction of human TFIID with the HIV-1 transactivator Tat

1994 • 251 citations

Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

1991 • 239 citations

Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core.

1994 • 238 citations

A cDNA for a Protein That Interacts with the Human Immunodeficiency Virus Tat Transactivator

1990 • 234 citations

Chromatin remodeling and transcription

1997 • 227 citations

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor

1993 • 218 citations

Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M.

1996 • 213 citations

What determines the folding of the chromatin fiber?

1996 • 204 citations

Adaptor-mediated Recruitment of RNA Polymerase II to a Signal-dependent Activator

1996 • 199 citations

NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro.

1996 • 188 citations

Nucleosome displacement in transcription

1993 • 179 citations

Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts.

1994 • 177 citations

DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1

1991 • 170 citations

Does HIV-1 Tat induce a change in viral initiation rights?

1993 • 166 citations

ATP-Dependent Nucleosome Reconfiguration and Transcriptional Activation from Preassembled Chromatin Templates

1994 • 163 citations

Tat is required for efficient HIV-1 reverse transcription

1997 • 143 citations

Tat-SF1: Cofactor for Stimulation of Transcriptional Elongation by HIV-1 Tat

1996 • 141 citations

The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function

1996 • 129 citations

Novel mechanism and factor for regulation by HIV-1 Tat.

1995 • 128 citations

The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes.

1993 • 121 citations

Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP.

1996 • 120 citations

The Human Immunodeficiency Virus Transactivator Tat Interacts with the RNA Polymerase II Holoenzyme

1997 • 111 citations

Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription

1997 • 111 citations

p300 and CBP as transcriptional regulators and targets of oncogenic events.

1996 • 110 citations

Human Chromosome 12 Is Required for Elevated HIV-1 Expression in Human-Hamster Hybrid Cells

1989 • 109 citations

Requirements for RNA Polymerase II Carboxyl-terminal Domain for Activated Transcription of Human Retroviruses Human T-Cell Lymphotropic Virus I and HIV-1

1996 • 105 citations

Chromatin structure and gene activity

1990 • 100 citations

Human chromosome 12 encodes a species-specific factor which increases human immunodeficiency virus type 1 tat-mediated trans activation in rodent cells

1990 • 94 citations

Human immunodeficiency viruses regulated by alternative trans-activators: genetic evidence for a novel non-transcriptional function of Tat in virion infectivity.

1994 • 93 citations

Molecular cloning and characterization of a cellular protein that interacts with the human immunodeficiency virus type 1 Tat transactivator and encodes a strong transcriptional activation domain

1995 • 81 citations

Effects of integration and replication on transcription of the HIV-1 long terminal repeat.

1993 • 79 citations

Opening the Way to Gene Activity

1997 • 72 citations

Evidence for Functional Interaction between the HIV-1 Tat Transactivator and the TATA Box Binding Proteinin Vivo

1995 • 71 citations

Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat.

1995 • 65 citations

Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II.

1996 • 62 citations

Transfer of Tat and release of TAR RNA during the activation of the human immunodeficiency virus type-1 transcription elongation complex

1997 • 60 citations

Isolation of a cellular protein that binds to the human immunodeficiency virus Tat protein and can potentiate transactivation of the viral promoter.

1991 • 59 citations

Differential Activity of Progesterone and Glucocorticoid Receptors on Mouse Mammary Tumor Virus Templates Differing in Chromatin Structure

1997 • 52 citations

Association of Tat with Purified HIV-1 and HIV-2 Transcription Preinitiation Complexes

1997 • 50 citations

Increased spacing between Sp1 and TATAA renders human immunodeficiency virus type 1 replication defective: implication for Tat function

1993 • 50 citations

In Vitro Chromatin Assembly of the HIV-1 Promoter

1997 • 49 citations

Refolding of barnase mutants and pro-barnase in the presence and absence of GroEL.

1993 • 48 citations

Different relative expression from two murine leukemia virus long terminal repeats in unintegrated transfected DNA and in integrated retroviral vector proviruses

1989 • 33 citations