Decoding the nucleosome

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1993 • 1,116 citations

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

1993 • 795 citations

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

1993 • 692 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei

1992 • 552 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

1991 • 372 citations

Control of transcription factors by signal transduction pathways: the beginning of the end

1992 • 360 citations

Histone Function in Transcription

1990 • 354 citations

Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.

1990 • 350 citations

Histone acetylation and control of gene expression

1991 • 331 citations

The maleless protein associates with the X chromosome to regulate dosage compensation in drosophila

1991 • 293 citations

Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains.

1991 • 269 citations

Histones and Their Modification

1986 • 260 citations

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

1991 • 242 citations

Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.

1992 • 186 citations

Stable nucleosome positioning and complete repression by the yeast alpha 2 repressor are disrupted by amino-terminal mutations in histone H4.

1992 • 160 citations

Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate.

1990 • 135 citations

Nucleosome linking number change controlled by acetylation of histones H3 and H4.

1990 • 132 citations

Antibodies to defined histone epitopes reveal variations in chromatin conformation and underacetylation of centric heterochromatin in human metaphase chromosomes

1992 • 128 citations

The Nucleosome

1981 • 125 citations

The identification of distinct populations of acetylated histone.

1980 • 122 citations

Histone acetylation and globin gene switching

1992 • 111 citations

The male-specific lethal-one (msl-1) gene of Drosophila melanogaster encodes a novel protein that associates with the X chromosome in males.

1993 • 105 citations

The Service Sector of the U.S. Economy

1981 • 89 citations

Isolation and characterization of acetylated histones H3 and H4 and their assembly into nucleosomes.

1990 • 71 citations

Effects of histone acetylation on chromatin topology in vivo.

1992 • 62 citations

Histone H4 acetylation and transcription in amphibian chromatin.

1993 • 61 citations

X chromosome dosage compensation in Drosophila

1993 • 22 citations

Inhibition of 5S RNA transcription in vitro by nucleosome cores with low or high levels of histone acetylation

1991 • 13 citations