The Coactivator CBP Stimulates Human T-cell Lymphotrophic Virus Type I Tax Transactivation in Vitro

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Role of CBP/P300 in nuclear receptor signalling

1996 • 935 citations

Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.

1984 • 886 citations

CREB-binding protein/p300 are transcriptional coactivators of p65

1997 • 819 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

Acetylation of general transcription factors by histone acetyltransferases

1997 • 588 citations

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

1995 • 578 citations

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

1995 • 534 citations

The pX Protein of HTLV-I Is a Transcriptional Activator of Its Long Terminal Repeats

1985 • 514 citations

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α

1996 • 492 citations

Two contact regions between Stat1 and CBP/p300 in interferon γ signaling

1996 • 486 citations

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1996 • 453 citations

CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.

1996 • 414 citations

Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.

1990 • 401 citations

Phosphorylation of CREB at Ser-133 Induces Complex Formation with CREB-Binding Protein via a Direct Mechanism

1996 • 396 citations

CBP as a transcriptional coactivator of c-Myb.

1996 • 347 citations

Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP

1996 • 344 citations

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1995 • 342 citations

p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation

1998 • 337 citations

Human p300 Protein Is a Coactivator for the Transcription Factor MyoD

1996 • 319 citations

Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction.

1992 • 318 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

Steroid receptor induction of gene transcription: A two-step model

1997 • 269 citations

The acetyltransferase activity of CBP stimulates transcription

1998 • 265 citations

Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat

1987 • 251 citations

Transcriptional control: Versatile molecular glue

1996 • 231 citations

Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract.

1987 • 228 citations

Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M.

1996 • 213 citations

Requirement of multiple copies of a 21-nucleotide sequence in the U3 regions of human T-cell leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription.

1986 • 212 citations

Adaptor-mediated Recruitment of RNA Polymerase II to a Signal-dependent Activator

1996 • 199 citations

MAP Kinase-Dependent Transcriptional Coactivation by Elk-1 and Its Cofactor CBP

1996 • 196 citations

Anchoring of CREB Binding Protein to the Human T-Cell Leukemia Virus Type 1 Promoter: a Molecular Mechanism of Tax Transactivation

1997 • 179 citations

Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer.

1986 • 175 citations

CREB-binding Protein Activates Transcription through Multiple Domains

1996 • 170 citations

SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein.

1996 • 151 citations

Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I.

1988 • 150 citations

Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax

1995 • 150 citations

Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax

1995 • 131 citations

Location of cis-acting regulatory sequences in the human T-cell leukemia virus type I long terminal repeat.

1985 • 127 citations

Human T-Cell Leukemia Virus Type 1 Tax Requires Direct Access to DNA for Recruitment of CREB Binding Protein to the Viral Promoter

1998 • 120 citations

Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP.

1996 • 120 citations

Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors

1995 • 119 citations

The CBP co-activator stimulates E2F1/DP1 activity

1996 • 117 citations

Requirements for RNA Polymerase II Carboxyl-terminal Domain for Activated Transcription of Human Retroviruses Human T-Cell Lymphotropic Virus I and HIV-1

1996 • 105 citations

E2F1 and E1A(12S) have a homologous activation domain regulated by RB and CBP.

1996 • 104 citations

Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes

1997 • 104 citations

Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB

1995 • 101 citations

Complex Formation between CREB and Tax Enhances the Binding Affinity of CREB for the Human T-Cell Leukemia Virus Type 1 21-Base-Pair Repeats

1996 • 83 citations

Evidence for Functional Interaction between the HIV-1 Tat Transactivator and the TATA Box Binding Proteinin Vivo

1995 • 71 citations

Quantitative studies of the effect of HTLV-I Tax protein on CREB protein - DNA binding

1994 • 68 citations

Definition of a minimal activation domain in human T-cell leukemia virus type I Tax

1995 • 58 citations

Interaction of the Human T-Cell Lymphotropic Virus Type 1 Tax Transactivator with Transcription Factor IIA

1996 • 55 citations

HTLV-1 21 bp Repeat Sequences Facilitate Stable Association Between Tax and CREB to Increase CREB Binding Affinity

1996 • 51 citations

HTLV-1 oncoprotein Tax deregulates transcription of cellular genes through multiple mechanisms

1995 • 48 citations

Electroporation of viral transactivator proteins into lymphocyte suspension cells

1992 • 45 citations

Differential Activation of Viral and Cellular Promoters by Human T-cell Lymphotropic Virus-1 Tax and cAMP-responsive Element Modulator Isoforms

1997 • 44 citations

Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA

1995 • 29 citations

Identification and Characterization of a Novel Transcriptional Activation Domain in the CREB-binding Protein

1996 • 23 citations

Differential precipitation and zinc chelate chromatography purification of biologically active HTLV-I Tax1 expressed in E. coli

1991 • 20 citations

Sarkosyl block of transcription reinitiation by RNA polymerase II as visualized by the colliding polymerases reinitiation assay

1994 • 19 citations