Nitric Oxide Improves Cisplatin Cytotoxicity in Head and Neck Squamous Cell Carcinoma

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data

2000 • 2,411 citations

Head and Neck Cancer

1993 • 2,263 citations

Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099.

1998 • 2,166 citations

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

1989 • 1,747 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

Cisplatin

1984 • 942 citations

Roles of nitric oxide in tumor growth.

1995 • 791 citations

Complexes of ^.NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

1991 • 724 citations

Nitric oxide synthase activity in human breast cancer

1995 • 637 citations

Nitric oxide synthase activity in human gynecological cancer.

1994 • 428 citations

Role of Nitric Oxide in Angiogenesis and Tumor Progression in Head and Neck Cancer

1998 • 427 citations

Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.

1986 • 421 citations

Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.

1995 • 326 citations

Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages

1991 • 280 citations

DNA Repair: Enzymatic Mechanisms and Relevance to Drug Response

1996 • 280 citations

Loss and Degradation of Enzyme-bound Heme Induced by Cellular Nitric Oxide Synthesis

1995 • 237 citations

Concurrent radiotherapy and chemotherapy with cisplatin in inoperable squamous cell carcinoma of the head and neck. An RTOG study

1987 • 210 citations

Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes

1995 • 197 citations

Inhibition by nitric oxide of the repair protein, O⁶-DNA-methyltransferase

1994 • 195 citations

Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release.

1993 • 137 citations

Nitric Oxide and Some Nitric Oxide Donor Compounds Enhance the Cytotoxicity of Cisplatin

1997 • 129 citations

Nitric oxide inhibits DNA ligase activity: potential mechanisms for NO-mediated DNA damage

1996 • 126 citations

Cisplatin

1999 • 120 citations

Simultaneous versus sequential combined technique therapy for squamous cell head and neck cancer

1990 • 116 citations

Immunohistochemical characterizationof nitric oxide synthase activity in squamous cell carcinoma of the head and neck

1995 • 110 citations

N^G-hydroxy-<scp>l</scp>-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms

1998 • 110 citations

Platinum analogs in recurrent and advanced head and neck cancer: a Southwest Oncology Group and Wayne State University Study.

1987 • 67 citations

Dual cell cycle-specific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells

1997 • 57 citations

Third Place — Resident Basic Science Award 1995: Immunohistochemical Characterization of Nitric Oxide Synthase Activity in Squamous Cell Carcinoma of the Head and Neck

1995 • 45 citations

Nitric oxide synthase activity in human squamous cell carcinoma of the head and neck

1999 • 34 citations

Introduction: Cisplatin update

1991 • 23 citations

Effects of endothelial nitric oxide synthase gene expression on the tumor biology of human oral carcinoma SCC-25 cells.

1998 • 18 citations

Nitric Oxide and Cancer

2000 • 14 citations