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Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease

Data up to Jan 2025

Published1995
Citations469
References33

Total Citations Per Year

Abstract

References (33)

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Enzymatic Determination of Total Serum Cholesterol

1974 • 9,182 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

The sphingomyelin cycle and the second messenger function of ceramide.

1994 • 1,255 citations

An improved culture medium supports development of random-bred 1-cell mouse embryos in vitro

1989 • 1,119 citations

The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling

1994 • 934 citations

Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells

1989 • 423 citations

The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick diseae.

1966 • 413 citations

Sphingomyelinase in normal human spleens and in spleens from subjects with Niemann-Pick disease

1967 • 302 citations

The Metabolism of Sphingomyelin

1966 • 248 citations

Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs

1991 • 210 citations

Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0

1976 • 173 citations

Rapid on-line determination of cholesterol distribution among plasma lipoproteins after high-performance gel filtration chromatography

1991 • 143 citations

Structural organization and complete nucleotide sequence of the gene encoding human acid sphingomyelinase (SMPD1)

1992 • 133 citations

Expression of retroviral vectors in transgenic mice obtained by embryo infection.

1987 • 128 citations

Affinity purification of alpha-galactosidase A from human spleen, placenta, and plasma with elimination of pyrogen contamination. Properties of the purified splenic enzyme compared to other forms.

1981 • 114 citations

[50] Production of chimeras between embryonic stem cells and embryos

1993 • 97 citations

Regional assignment of the human acid sphingomyelinase gene (SMPD1) by PCR analysis of somatic cell hybrids and in situ hybridization to 11p15.1→p15.4

1991 • 81 citations

Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior.

1994 • 77 citations

[52] Simple screening procedure to detect gene targeting events in embryonic stem cells

1993 • 59 citations

Effect of Triton X-100 on the hydrolysis of sphingomyelin by sphingomyelinase of rat brain

1976 • 41 citations

Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cells.

1992 • 33 citations

[52] Human acid sphingomyelinase from human urine

1991 • 33 citations

Molecular Cloning of the Acid Sphingomyelinase of the Mouse and the Organization and Complete Nucleotide Sequence of the Gene

1992 • 31 citations

Purification and Characterization of Neutral and Acid Sphingomyelinases from Rat Brain

1989 • 27 citations

NIEMANN PICK DISEASE: PRESENCE OF THE MAGNESIUM‐DEPENDENT SPHINGOMYELINASE IN BRAIN OF THE INFANTILE FORM OF THE DISEASE1

1978 • 27 citations

Toward Gene Therapy for Niemann-Pick Disease (NPD): Separation of Retrovirally Corrected and Noncorrected NPD Fibroblasts Using a Novel Fluorescent Sphingomyelin

1992 • 21 citations

Mouse Models of Niemann-Pick Disease: Mutation Analysis and Chromosomal Mapping Rule Out the Type A and B Forms

1993 • 10 citations

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Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease (1995) – Nature Genetics | Metascience Observatory Explorer