Nuclear accumulation of Smad complexes occurs only after the midblastula transition inXenopus

Normal Table of Xenopus Laevis (Daudin)

1958 • 4,561 citations

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

2002 • 2,692 citations

A monomeric red fluorescent protein

2002 • 2,344 citations

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

1982 • 1,635 citations

Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation

2002 • 1,516 citations

A major developmental transition in early xenopus embryos: II. control of the onset of transcription

1982 • 1,065 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Circularly permuted green fluorescent proteins engineered to sense Ca ²⁺

2001 • 941 citations

The nuclear lamina comes of age

2005 • 828 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

2003 • 767 citations

Nodal signaling: developmental roles and regulation

2007 • 513 citations

Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells

2006 • 511 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Identification of New Fluorescent Protein Fragments for Bimolecular Fluorescence Complementation Analysis Under Physiological Conditions

2006 • 384 citations

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

1997 • 365 citations

Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis

2000 • 341 citations

Microtubule Binding to Smads May Regulate TGFβ Activity

2000 • 277 citations

β-catenin, MAPK and Smad signaling during earlyXenopusdevelopment

2002 • 265 citations

Endogenous patterns of TGFβ superfamily signaling during early Xenopus development

2000 • 256 citations

Patterning the earlyXenopusembryo

2006 • 243 citations

Crystal Structure of Venus, a Yellow Fluorescent Protein with Improved Maturation and Reduced Environmental Sensitivity

2002 • 193 citations

Gastrulation movements provide an early marker of mesoderm induction in Xenopus laevis

1987 • 172 citations

Transforming Growth Factor-β Induces Nuclear Import of Smad3 in an Importin-β1 and Ran-dependent Manner

2001 • 165 citations

Analysis of Smad nucleocytoplasmic shuttling in living cells

2004 • 135 citations

Analysis of competence and of Brachyury autoinduction by use of hormoneinducible Xbra

1997 • 121 citations

Distinct Oligomeric States of SMAD Proteins in the Transforming Growth Factor-β Pathway

2000 • 118 citations

Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of fibronectin and integrins

1990 • 116 citations

Timing of endogenous activin-like signals and regional specification of theXenopusembryo

2001 • 112 citations

The organization of mesodermal pattern inXenopus laevis:experiments using aXenopusmesoderm-inducing factor

1987 • 110 citations

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

2002 • 106 citations

Stoichiometry of Active Smad-Transcription Factor Complexes on DNA

2002 • 90 citations

The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during earlyXenopusdevelopment but do not co-operate to establish thresholds

1997 • 83 citations

Kinesin-Mediated Transport of Smad2 Is Required for Signaling in Response to TGF-β Ligands

2007 • 78 citations

Crystal structure of a transcriptionally active Smad4 fragment

1999 • 64 citations

A changing morphogen gradient is interpreted by continuous transduction flow

2002 • 62 citations

Activin redux: specification of mesodermal pattern inXenopusby graded concentrations of endogenous activin B

2004 • 57 citations

Measurement of developmental time by cells of early embryos

1990 • 53 citations

What MAN1 does to the Smads

2007 • 51 citations

Differential accumulation of oocyte nuclear proteins by embryonic nuclei ofXenopus

1987 • 45 citations

A Xenopus tribbles orthologue is required for the progression of mitosis and for development of the nervous system

2004 • 28 citations

Xenopus Smad3 is specifically expressed in the chordoneural hinge, notochord and in the endocardium of the developing heart

2001 • 26 citations